Phenolic glycosides from Sanguisorba officinalis and their anti-inflammatory effects

2020 ◽  
pp. 1-8
Author(s):  
Jin-feng Chen ◽  
Lu Tan ◽  
Feng Ju ◽  
Qi-xuan Kuang ◽  
Tian-long Yang ◽  
...  
2010 ◽  
Vol 18 (17) ◽  
pp. 6598-6602 ◽  
Author(s):  
Sarot Cheenpracha ◽  
Eun-Jung Park ◽  
Wesley Y. Yoshida ◽  
Chaz Barit ◽  
Marisa Wall ◽  
...  

2020 ◽  
pp. 1-10
Author(s):  
Rongshen Wang ◽  
Jinfeng Sun ◽  
Mei Jin ◽  
Chao Ye ◽  
Jiaming Wang ◽  
...  

Molecules ◽  
2017 ◽  
Vol 22 (6) ◽  
pp. 1023 ◽  
Author(s):  
Joon Cha ◽  
Won Suh ◽  
Tae Lee ◽  
Lalita Subedi ◽  
Sun Kim ◽  
...  

Planta Medica ◽  
2006 ◽  
Vol 72 (10) ◽  
pp. 948-950 ◽  
Author(s):  
Hai-Ming Shi ◽  
Jing Wen ◽  
Cun-Qin Jia ◽  
Wei Jin ◽  
Xiu-Feng Zhang ◽  
...  

2014 ◽  
Vol 24 (1) ◽  
pp. 356-361 ◽  
Author(s):  
Yonghui Xie ◽  
Songhua Yu ◽  
Hongdong Liu ◽  
Dongming Zhang ◽  
Xuewen Lai ◽  
...  

2015 ◽  
Vol 78 (7) ◽  
pp. 1586-1592 ◽  
Author(s):  
Li-Jie Zhang ◽  
Hung-Tse Huang ◽  
Shih-Yen Huang ◽  
Zhi-Hu Lin ◽  
Chien-Chang Shen ◽  
...  

2021 ◽  
Vol 2 (1) ◽  
pp. 25-31
Author(s):  
Sharonova Mohidil Amanovna ◽  
Rashit Rakhimovich Rakhmonov ◽  
Zulfikarov Abdurayim Naimovich

 LAGERSTROEMIA INDICA L. has anti-inflammatory, analgesic, antipyretic, antioxidant, anticancer, antimicrobial, Alzheimer's, antidiabetic, hepatoprotective and antithrombin effects. 1,3,5-Trimethylbenzene, n-Undekan, Pelargonaldehyde, n-Dodekan, 1,1-Dibutoxibutane, Triacetylglycerin, 4,4,7a-trimethyl-5,6,7,7a-tetrahydrobenzofuran-2 (4H) –on, tsis-Pinan, neophytadiene, chlorpyrifos, alkaloids, cardiac glycosides, tannins, saponins, sterols, triterpenes, anthraquinones, reducing compounds, flavonoids (flavanones / dihydroflavonols and chalcones) and phenolic glycosides. This article discusses the chemical composition, components, and pharmacological effects of Indian lagerstroemia indica L


2020 ◽  
Vol 19 (9) ◽  
pp. 1993-1998
Author(s):  
Mohammad Saydur Rahman ◽  
Irshad Ali ◽  
Madeeha Arooj ◽  
Xiang Dong Su ◽  
Seo Young Yang ◽  
...  

Purpose: To evaluate the anti-inflammatory effect of methyl-4-(β-D-glucopyranosyloxy)-3-hydroxy-5-methoxybenzoate (comp-1) on immune cells.Methods: Comp-1 was isolated from Sanguisorba officinalis. After treating with comp-1, cell viability and levels of pro-inflammatory cytokines were assessed utilizing MTT assay and ELISA, respectively. Besides, the effects of comp-1 on nuclear factor kappa B (NF-κB), mitogen-activated protein kinase (MAPK), and iNOS were determined using western blotting. Moreover, nitric oxide production was assessed using the Griess reagent.Results: Treatment of dendritic cells (DCs) with CpG DNA upregulated cytokine expression. Comp-1 markedly downregulated the expressions of IL-12 p40, IL-6, and TNF-α, with 50% inhibitory concentrations (IC50) of 1.077 ± 0.04 (p < 0.01), 0.28 ± 0.01 (p < 0.01), and 0.79 ± 0.02 μM (p < 0.01),respectively. Treatment of DCs with CpG DNA upregulated NF-κB and MAPK activation. However, pretreatment of the cells with Comp-1 suppressed CpG DNA-induced NF-κB and MAPK activation. Moreover, comp-1 exhibited a strong anti-inflammatory effect by inhibiting nitric oxide production and iNOS expression.Conclusion: These results reveal that comp-1 has significant anti-inflammatory effect on immune cells. Keywords: Natural compound, Inflammation, Pro-inflammatory cytokine, Toll-like receptor9


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