Potential anti-inflammatory phenolic glycosides from the medicinal plant Moringa oleifera fruits

LAGERSTROEMIA INDICA L. has anti-inflammatory, analgesic, antipyretic, antioxidant, anticancer, antimicrobial, Alzheimer's, antidiabetic, hepatoprotective and antithrombin effects. 1,3,5-Trimethylbenzene, n-Undekan, Pelargonaldehyde, n-Dodekan, 1,1-Dibutoxibutane, Triacetylglycerin, 4,4,7a-trimethyl-5,6,7,7a-tetrahydrobenzofuran-2 (4H) –on, tsis-Pinan, neophytadiene, chlorpyrifos, alkaloids, cardiac glycosides, tannins, saponins, sterols, triterpenes, anthraquinones, reducing compounds, flavonoids (flavanones / dihydroflavonols and chalcones) and phenolic glycosides. This article discusses the chemical composition, components, and pharmacological effects of Indian lagerstroemia indica L

Download Full-text

Antioxidant, anti-inflammatory and anti-nociceptive effects of Ammannia baccifera L. (Lythracceae), a folklore medicinal plant

Journal of Ethnopharmacology ◽

10.1016/j.jep.2012.01.001 ◽

2012 ◽

Vol 140 (2) ◽

pp. 230-233 ◽

Cited By ~ 18

Author(s):

Nataraj Loganayaki ◽

Perumal Siddhuraju ◽

Sellamuthu Manian

Keyword(s):

Medicinal Plant ◽

Anti Inflammatory

Download Full-text

Anti-Inflammatory Activity of Cnidoscolus aconitifolius (Mill.) Ethyl Acetate Extract on Croton Oil-Induced Mouse Ear Edema

Applied Sciences ◽

10.3390/app11209697 ◽

2021 ◽

Vol 11 (20) ◽

pp. 9697

Author(s):

Eduardo Padilla-Camberos ◽

Omar Ricardo Torres-Gonzalez ◽

Ivan Moises Sanchez-Hernandez ◽

Nestor Emmanuel Diaz-Martinez ◽

Oscar Rene Hernandez-Perez ◽

...

Keyword(s):

Medicinal Plant ◽

Ethyl Acetate ◽

Ethyl Acetate Extract ◽

Inflammatory Activity ◽

Therapeutic Effects ◽

Ear Edema ◽

Croton Oil ◽

Mouse Ear ◽

Anti Inflammatory ◽

Mouse Ear Edema

Nowadays, there is a growing interest in the development of medicinal plant-based therapies to diminish the ravages of the inflammatory process related to diseases and tissue damage. Most therapeutic effects of these traditional medicinal plants are owed to their phenolic and antioxidant properties. C. aconitifolius is a traditional medicinal plant in Mexico. Previous characterization reports have stated its high nutritional and antioxidant components. The present study aimed to better understand the biological activity of C. aconitifolius in inflammation response. We developed an ethyl acetate extract of this plant to evaluate its anti-inflammatory capacity and its flavonoid content. The topical anti-inflammatory effect of the ethyl acetate extract of C. aconitifolius was determined by the croton oil-induced mouse ear edema test, while flavonoid detection and concentration were determined by thin layer chromatography and the aluminum chloride colorimetric assay, respectively. Topical application of the extract showed significant inhibition of the induced-ear edema (23.52 and 49.41% for 25 and 50 mg/kg dose, respectively). The extract also exhibited the presence of flavonoids. The finding of the anti-inflammatory activity exerted by the C. aconitifolius and the identification of its active principles may suggest and support its use for inflammation treatment.

Download Full-text

AN UPDATED REVIEW ON USTUKHUDOOS PLANT

Journal of Drug Delivery and Therapeutics ◽

10.22270/jddt.v8i5.1855 ◽

2018 ◽

Vol 8 (5) ◽

pp. 88-91

Author(s):

Aisha Siddiqui ◽

Zeba Afrin ◽

MA Jafri

Keyword(s):

Essential Oil ◽

Medicinal Plant ◽

Facial Paralysis ◽

Neurological Disorders ◽

Scientific Research ◽

Urinary Disorders ◽

Liver Disorders ◽

Lavandula Stoechas ◽

Anti Inflammatory ◽

Important Medicinal Plant

Lavandula stoechas Mill. commonly known as Ustukhudoos, is perhaps the most important medicinal plant in the unani system of medicine. Whole part, flowers and essential oil of the plant is used to treat a variety of diseases. A number of ailments are treated by the plant which is used either alone or in combination with other plants. It is used for the treatment of various neurological disorders like hemiplegia, facial paralysis, tremors, epilepsy, melancholia, neurasthenia. Moreover, it is used in sinusitis, liver disorders and urinary disorders etc. L. stoechas possesses antimicrobial, antidiabetic, antioxidant, antifungal, anti-inflammatory, anticonvulsant, antispasmodic, sedative, hepatoprotective activities. This article discusses and summarizes the important medicinal values of Ustukhudoos in the perspective of Unani literature as well as modern scientific research. Keywords: Ustukhudoos, Lavandula stoechas, neurological, epilepsy

Download Full-text

Anti-Inflammatory Activity and Composition ofSenecio salignusKunth

BioMed Research International ◽

10.1155/2013/814693 ◽

2013 ◽

Vol 2013 ◽

pp. 1-4 ◽

Cited By ~ 4

Author(s):

Cuauhtemoc Pérez González ◽

Roberto Serrano Vega ◽

Marco González-Chávez ◽

Miguel Angel Zavala Sánchez ◽

Salud Pérez Gutiérrez

Keyword(s):

Medicinal Plant ◽

Methanol Extract ◽

Chloroform Extract ◽

Inflammatory Activity ◽

Paw Edema ◽

Active Fraction ◽

Ear Edema ◽

Methanol Extracts ◽

Anti Inflammatory ◽

Inflammatory Effect

We investigated the anti-inflammatory activity ofSenecio salignus. This medicinal plant is often used in Mexico for the treatment of fever and rheumatism. Chloroform and methanol extracts of the plant were tested on 12-O-tetradecanoylphorbol-13-acetate- (TPA-) induced edema in mice ears. The methanol extract of the plant inhibited edema by36±4.4% compared with the control, while the chloroform extract exhibited an even greater level of inhibition (64.1%). The chloroform extract was then fractionated, and the composition of the active fraction was determined by GC-MS. The anti-inflammatory activity of this fraction was then tested on TPA-induced ear edema in mice, and we found that the active fraction could inhibit edema by 46.9%. The anti-inflammatory effect of the fraction was also tested on carrageenan-induced paw edema in rats at doses of 100 mg/kg; a58.9±2.8% reduction of the edema was observed 4 h after administration of carrageenan, and the effect was maintained for 5 h.

Download Full-text

Anti-Inflammatory Constituents of Alchornea cordifolia Leaves

Nigerian Journal of Natural Products and Medicine ◽

10.4314/njnpm.v19i0.5 ◽

2015 ◽

Vol 19 ◽

pp. 60-64

Author(s):

AA Ahmadu ◽

A Agunu ◽

EM Abdurrahman

Keyword(s):

Medicinal Plant ◽

West Africa ◽

Ethyl Acetate ◽

Leaf Extract ◽

Methyl Gallate ◽

Paw Oedema ◽

Analgesic Agents ◽

Anti Inflammatory ◽

Rat Paw ◽

Rat Paw Oedema

Alchornea cordifolia (Schum and Thonn) Muell. Arg. (Euphorbiaceae) is a traditional medicinal plant widely distributed in West Africa including Nigeria.The plant has been used for ethnomedicinal purposes against wounds, ulcers, and sores. The decoction of the leaves has been reported to provide remedies for bronchial problems, rheumatic pain and cough. From the dichloromethane and ethyl acetate soluble parts of the Methanol leaf extract, two compounds namely Lup-20(29)-en-3c-ol (lupenol) and Methyl 3, 4,5-trihydroxy benzoate (Methyl gallate) were isolated and their structures elucidated. Anti-inflammatory and analgesic properties of the compounds on carrageenan-induced paw oedema and formalin-induced pain in rats showed that compound 2 significantly (P<0.05) inhibit rat paw oedema compared to the standard drugs (Piroxicam and Morphine) used, while on formalin-induced pain in rats, the same trend was observed and were both comparable to Piroxicam and morphine, the standard anti-inflammatory and analgesic agents used, respectively. Compound 1 did not show any significant anti-inflammatory activity compared to control, likewise compound 2. Thus, compound 2, Methyl trihydroxy benzoate, might be responsible for the anti-inflammatory and analgesic properties of this plant.Keywords: Alchornea cordifolia, Anti-inflammatory, Analgesic, Methyl Trihydroxy Benzoate

Download Full-text