The Importance of Mental Pain and Physical Dissociation in Youth Suicidality

2015 ◽  
Vol 16 (3) ◽  
pp. 322-339 ◽  
Author(s):  
Shai Levinger ◽  
Eli Somer ◽  
Ronald R. Holden
Keyword(s):  
Mental Pain ◽  
Physical Dissociation

Examining the Importance of Mental Pain and Physical Dissociation and the Fluid Nature of Suicidality in Young Suicide Attempters

2015 ◽  
Vol 73 (2) ◽  
pp. 159-173 ◽  
Author(s):  
Shai Levinger ◽  
Ronald R. Holden ◽  
David H. Ben-Dor
Keyword(s):  
Suicide Attempt ◽  
Pain Tolerance ◽  
Suicide Attempters ◽  
Mental Pain ◽  
Relevant Variables ◽  
Physical Dissociation

This study evaluated the importance of distress (i.e., mental pain, tolerance of mental pain, and depression) and physical dissociation factors for a group of young suicide attempters. Analyses indicated that those with higher current suicidality also evidenced higher current levels of depression and mental pain, lower mental pain tolerance, and higher physical dissociation. However, no correlations between suicidality and distress or physical dissociation were found when the level of suicidality was based on the time of the suicide attempt. The results demonstrate the importance of mental pain and its tolerance as well as physical dissociation in assessing severity of suicidality. However, analyses suggest there might be a decline in suffering after a suicide attempt and highlight the importance of assessing current suicidality when evaluating relevant variables for suicide. Findings are interpreted with regard to theories relating to the fluctuating nature of suicidality.

Tolerance for Mental Pain Scale--10 Items; Turkish Version

2019 ◽  
Author(s):  
Mehmet Emin Demirkol ◽  
Lut Tamam ◽  
Zeynep Namlı ◽  
Özge Eriş Davul
Keyword(s):  
Pain Scale ◽  
Turkish Version ◽  
Mental Pain

Tolerance for Mental Pain Scale-10--Italian Version

2020 ◽  
Author(s):  
Giulia Landi ◽  
Annalisa Furlani ◽  
Giada Boccolini ◽  
Mario Mikulincer ◽  
Silvana Grandi ◽  
...  
Keyword(s):  
Pain Scale ◽  
Italian Version ◽  
Mental Pain

scholarly journals Physical dissociation of the TCR-CD3 complex accompanies receptor ligation.

1995 ◽  
Vol 182 (6) ◽  
pp. 1997-2006 ◽  
Author(s):  
H Kishimoto ◽  
R T Kubo ◽  
H Yorifuji ◽  
T Nakayama ◽  
Y Asano ◽  
...  
Keyword(s):  
Flow Cytometry ◽  
Cell Surface ◽  
Molecular Mechanisms ◽  
Signal Transduction Pathway ◽  
Surface Expression ◽  
Cell Surface Expression ◽  
Protein Levels ◽  
Before And After ◽  
Physical Dissociation ◽  
Receptor Ligation

Recent studies indicate that there may be functional uncoupling of the TCR-CD3 complex and suggest that the TCR-CD3 complex is composed of two parallel signal-transducing units, one made of gamma delta epsilon chains and the other of zeta chains. To elucidate the molecular mechanisms that may explain the functional uncoupling of TCR and CD3, we have analyzed their expression by using flow cytometry as well as immunochemical means both before and after stimulation with anti-TCR-beta, anti-CD3 epsilon, anti-CD2, staphylococcal enterotoxin B, and ionomycin. We present evidence that TCR physically dissociates from CD3 after stimulation of the TCR-CD3 complex. Stimulation with anti-CD3 resulted in down-modulation of TCR within 45 min whereas CD3 epsilon was still expressed on the cell surface as detected by flow cytometry. However, the cell surface expression of TCR and CD3 was not affected when cells were stimulated with anti-TCR-beta under the same conditions. In the case of anti-CD3 treatment of T cells, the TCR down-modulation appeared to be due to the internalization of TCR, as determined by immunoelectron microscopy. Immunochemical analysis of cells after stimulation with either anti-TCR or anti-CD3 mAbs revealed that the overall protein levels of TCR and CD3 were similar. More interestingly, the dissociation of the TCR-CD3 complex was observed with both treatments and occurred in a manner that the TCR and the associated TCR-zeta chain dissociated as a unit from CD3. These results provide the first report of physical dissociation of TCR and CD3 after stimulation through the TCR-CD3 complex. The results also suggest that the signal transduction pathway triggered by TCR may differ from that induced by CD3.

Validation of a Chinese version of the Tolerance for Mental Pain Scale-10 with Chinese college students

2021 ◽  
Vol 49 (12) ◽  
pp. 1-8
Author(s):  
Ning Cui ◽  
Yingshan Bao ◽  
Xiaoming Liu ◽  
Kangyi Liu ◽  
Weiyu Chen
Keyword(s):  
College Students ◽  
Factor Analysis ◽  
Factor Model ◽  
Pain Scale ◽  
Two Dimensions ◽  
Chinese Version ◽  
Psychological Pain ◽  
Chinese College Students ◽  
Mental Pain ◽  
Psychometric Tool

We built and validated a Chinese version of the Tolerance for Mental Pain Scale-10 (TMPS-10). Participants were 840 college students in Jilin, China. The TMPS-10 consists of two dimensions: managing the pain and enduring the pain. In our study Cronbach's alphas were .80 and .83, respectively, and test–retest reliability coefficients were .78 and .72, respectively, for these two dimensions. Exploratory factor analysis results demonstrate that the two dimensions accounted for 61.58% of the total variance. Confirmatory factor analysis results show that the two-factor model fit the sample data well. As the Chinese version of the TMPS-10 meets the requirements for a psychometric tool, it can be used to evaluate Chinese college students' tolerance of psychological pain.

‘I feel your pain’: some reflections on the (literary) perception of pain

2017 ◽  
Author(s):  
Jonathan Sawday
Keyword(s):  
Eighteenth Century ◽  
New Technologies ◽  
17Th Century ◽  
King Lear ◽  
Source Text ◽  
Mental Pain ◽  
Cognitive Studies ◽  
The Way

In this chapter, Jonathan Sawday looks at some examples of the representation of pain on the renaissance stage, concentrating on the language which is deployed to reproduce the sensation of both physical and mental pain. Using Shakespeare’s King Lear as his source text, Sawday looks at the way in which eighteenth-century commentators (chiefly Dr Johnson) responded to the play’s ‘painfulness’. Sawday argues that, rather than seeing Johnson’s response as ‘excessive,’ it faithfully rehearses a theory of pain derived (in part) from Locke. Sawday goes on to examine the nature of ‘word-induced’ pain which has become a feature of modern cognitive studies of pain, and which might suggest that Johnson’s reaction to the play may, in fact, have some somatic basis. He concludes by suggesting the possibility that 16th- and 17th-century rehearsals of pain via the medium of metaphoric and devotional language may also have a somatic basis, and one which, with the arrival of new technologies for understanding the location and nature of pain, we are only just beginning to (re-)discover.

Do the Arahant and the Buddha Experience Dukkha and Domanassa?

2019 ◽  
Vol 36 (1) ◽  
pp. 53-70
Author(s):  
Ashin Sumanacara
Keyword(s):  
Human Beings ◽  
Physical Pain ◽  
Physical Disease ◽  
Mental Pain ◽  
Different Types ◽  
Unpleasant Feeling ◽  
The Buddha

The P?li Nik?yas describe a range of painful feelings that are experienced by human beings. The painful feelings are primarily divided into the categories of dukkha and domanassa. In its broader sense, dukkha covers a complete range of different types of painful or unpleasant feeling. But when it appears within a compound or together with domanassa successively within a passage, its meaning is primarily limited to physical pain while domanassa refers to mental pain. This article investigates the question of whether or not the Arahant and the Buddha experience mental pain as well as physical pain. My analysis of doctrinal explanations demonstrates that the Arahant and the Buddha are subject to experience physical pain and physical disease but not mental pain. This article also clarifies why and to what degree the P?li tradition sees them as experiencing physical pain and disease.

Mental Pain and Euthymia as Transdiagnostic Clinimetric Indices in Primary Care

2019 ◽  
Vol 88 (4) ◽  
pp. 252-253 ◽  
Author(s):  
Jenny Guidi ◽  
Antonio Piolanti ◽  
Sara Gostoli ◽  
Isabel Schamong ◽  
Eva-Lotta Brakemeier
Keyword(s):  
Primary Care ◽  
Mental Pain
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