Maternal environment and genetic mechanisms that regulate primary dormancy and the rate of dormancy loss in barley seeds

2021 ◽  
pp. 1-18
Author(s):  
Elias Soltani ◽  
Zahra Sadat Taheripourfard ◽  
Habibollah Ghazvini ◽  
Ali Izadi- Darbandi
Keyword(s):  
Maternal Environment ◽  
Primary Dormancy ◽  
Genetic Mechanisms

Molecular and Genetic Mechanisms of Factor XIII A Subunit Deficiency

2000 ◽  
Vol Volume 26 (Number 01) ◽  
pp. 005-010 ◽  
Author(s):  
Akitada Ichinose ◽  
Masayoshi Souri ◽  
Tomonori Izumi ◽  
Nobumasa Takahashi
Keyword(s):  
Factor Xiii ◽  
Genetic Mechanisms ◽  
A Subunit

Molecular and genetic mechanisms of pathological processes development (VIII Congress of the International Society of Pathophysiology)

2018 ◽  
pp. 281-284
Author(s):  
А.В. Кубышкин ◽  
П.Ф. Литвицкий ◽  
Л.П. Чурилов ◽  
О. Пеханова ◽  
О.И. Уразова ◽  
...  
Keyword(s):  
International Society ◽  
Genetic Mechanisms

В статье приводятся данные об основных тенденциях и направлениях развития патофизиологии как науки и образовательной дисциплины, представленных на VIII конгрессе Международного общества патофизиологов в Братиславе. The article provides information of the main trends and directions of development of Pathophysiology as a science and educational discipline, which presented at the VIII Congress of the International Society of Pathophysiology in Bratislava.

Immune and Genetic Mechanisms in COPD: Possible Targets for Therapeutic Interventions

2013 ◽  
Vol 14 (2) ◽  
pp. 141-148 ◽  
Author(s):  
Eleni G. Tzortzaki ◽  
Alberto Papi ◽  
Eirini Neofytou ◽  
Nikolaos Soulitzis ◽  
Nikolaos M. Siafakas
Keyword(s):  
Therapeutic Interventions ◽  
Genetic Mechanisms

scholarly journals Editorial: Evolution of Genetic Mechanisms of Antibiotic Resistance

2019 ◽  
Vol 10 ◽  
Author(s):  
Silvia Buroni ◽  
Simona Pollini ◽  
Gian Maria Rossolini ◽  
Elena Perrin
Keyword(s):  
Antibiotic Resistance ◽  
Genetic Mechanisms

scholarly journals Genome-Wide Analysis of Sex Disparities in the Genetic Architecture of Lung and Colorectal Cancers

Genes ◽  
2021 ◽  
Vol 12 (5) ◽  
pp. 686
Author(s):  
Alireza Nazarian ◽  
Alexander M. Kulminski
Keyword(s):  
Nucleotide Polymorphisms ◽  
Genetic Associations ◽  
Significance Level ◽  
Association Analyses ◽  
Complex Disorders ◽  
Specific Effects ◽  
Genome Wide ◽  
Genetic Mechanisms ◽  
Sex Disparities ◽  
Almost All

Almost all complex disorders have manifested epidemiological and clinical sex disparities which might partially arise from sex-specific genetic mechanisms. Addressing such differences can be important from a precision medicine perspective which aims to make medical interventions more personalized and effective. We investigated sex-specific genetic associations with colorectal (CRCa) and lung (LCa) cancers using genome-wide single-nucleotide polymorphisms (SNPs) data from three independent datasets. The genome-wide association analyses revealed that 33 SNPs were associated with CRCa/LCa at P < 5.0 × 10−6 neither males or females. Of these, 26 SNPs had sex-specific effects as their effect sizes were statistically different between the two sexes at a Bonferroni-adjusted significance level of 0.0015. None had proxy SNPs within their ±1 Mb regions and the closest genes to 32 SNPs were not previously associated with the corresponding cancers. The pathway enrichment analyses demonstrated the associations of 35 pathways with CRCa or LCa which were mostly implicated in immune system responses, cell cycle, and chromosome stability. The significant pathways were mostly enriched in either males or females. Our findings provided novel insights into the potential sex-specific genetic heterogeneity of CRCa and LCa at SNP and pathway levels.

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