Agreement between anterior segment parameters obtained by a new ultrasound biomicroscopy and a swept-source fourier-domain anterior segment optical coherence tomography.

Background: The present study determined the mean reference values of the anterior segment parameters of the selected eye using swept source optical coherence tomography (SS-OCT) in healthy Caucasian participants. Methods: A total of 166 volunteers (age 54–79 years), women (n = 92) and men (n = 74), were analyzed. One eye of each subject was randomly selected for anterior segment imaging. The anterior segment of the eye was scanned with CASIA2. The analyzed anterior segment parameters were divided into three groups, namely parameters of the cornea, lens, and angle. Results: The OCT (e.g., Ks, Kf, pKf, pKs, and central corneal thickness) and Fourier parameters of the cornea were significantly different between females and males. The iridocorneal angle was the smallest in the upper quadrant for all distance from the apex of the angle (250, 500, and 750 µm). Conclusions: Therefore, SS-OCT enables the analysis of parameters of the cornea, anterior chamber, lens, and iridocorneal angle, highlighting its clinical utility. Sex-specific differences in the analyzed parameters should be taken into account during the diagnosis of corneal diseases. The configuration of the filtration angle is an important marker during glaucoma diagnosis and drainage implant surgery. Measurements with CASIA 2is characterized by very good repeatability.

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Assessment of corneal thickness measurement using swept-source Fourier-domain anterior segment optical coherence tomography and Scheimpflug camera

Journal of Cataract & Refractive Surgery ◽

10.1016/j.jcrs.2012.05.004 ◽

2012 ◽

Vol 38 (7) ◽

pp. 1305-1306 ◽

Cited By ~ 2

Author(s):

Jinhai Huang ◽

Yifan Feng ◽

Qinmei Wang ◽

Konrad Pesudovs

Keyword(s):

Optical Coherence Tomography ◽

Corneal Thickness ◽

Anterior Segment ◽

Thickness Measurement ◽

Fourier Domain ◽

Optical Coherence ◽

Swept Source ◽

Scheimpflug Camera

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Agreement between Gonioscopic Examination and Swept Source Fourier Domain Anterior Segment Optical Coherence Tomography Imaging

Journal of Ophthalmology ◽

10.1155/2016/1727039 ◽

2016 ◽

Vol 2016 ◽

pp. 1-8 ◽

Cited By ~ 15

Author(s):

Mohammed Rigi ◽

Nicholas P. Bell ◽

David A. Lee ◽

Laura A. Baker ◽

Alice Z. Chuang ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Anterior Segment ◽

Fourier Domain ◽

Optical Coherence ◽

Swept Source ◽

Tomography Imaging ◽

Narrow Angle ◽

Optical Coherence Tomography Imaging ◽

The Mean ◽

Classification Agreement

Purpose. To evaluate interobserver, intervisit, and interinstrument agreements for gonioscopy and Fourier domain anterior segment optical coherence tomography (FD ASOCT) for classifying open and narrow angle eyes. Methods. Eighty-six eyes with open or narrow anterior chamber angles were included. The superior angle was classified open or narrow by 2 of 5 glaucoma specialists using gonioscopy and imaged by FD ASOCT in the dark. The superior angle of each FD ASOCT image was graded as open or narrow by 2 masked readers. The same procedures were repeated within 6 months. Kappas for interobserver and intervisit agreements for each instrument and interinstrument agreements were calculated. Results. The mean age was 50.9 (±18.4) years. Interobserver agreements were moderate to good for both gonioscopy (0.57 and 0.69) and FD ASOCT (0.58 and 0.75). Intervisit agreements were moderate to excellent for both gonioscopy (0.53 to 0.86) and FD ASOCT (0.57 and 0.85). Interinstrument agreements were fair to good (0.34 to 0.63), with FD ASOCT classifying more angles as narrow than gonioscopy. Conclusions. Both gonioscopy and FD ASOCT examiners were internally consistent with similar interobserver and intervisit agreements for angle classification. Agreement between instruments was fair to good, with FD ASOCT classifying more angles as narrow than gonioscopy.

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Lower Tear Meniscus Measurements Using a New Anterior Segment Swept-Source Optical Coherence Tomography and Agreement With Fourier-Domain Optical Coherence Tomography

Cornea ◽

10.1097/ico.0000000000001086 ◽

2017 ◽

Vol 36 (2) ◽

pp. 183-188 ◽

Cited By ~ 8

Author(s):

Pedro Arriola-Villalobos ◽

José Ignacio Fernández-Vigo ◽

David Díaz-Valle ◽

Jaime Almendral-Gómez ◽

Cristina Fernández-Pérez ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Anterior Segment ◽

Fourier Domain ◽

Optical Coherence ◽

Swept Source ◽

Tear Meniscus

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Comparison of the swept-source anterior segment optical coherence tomography and wide-field ultrasound biomicroscopy for imaging previously operated horizontal extraocular muscles

Journal of American Association for Pediatric Ophthalmology and Strabismus ◽

10.1016/j.jaapos.2021.03.007 ◽

2021 ◽

Author(s):

Savleen Kaur ◽

Jaspreet Sukhija ◽

Shagun Korla ◽

Kulbhushan Sachdeva ◽

Shweta Chaurasia ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Anterior Segment ◽

Ultrasound Biomicroscopy ◽

Extraocular Muscles ◽

Wide Field ◽

Optical Coherence ◽

Swept Source

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Pediatric Free-floating Anterior Chamber Cyst of the Iris Pigment Epithelium

American Journal of Ophthalmic Clinical Trials ◽

10.25259/ajoct-5-2018 ◽

2018 ◽

Vol 1 ◽

pp. 3

Author(s):

Joshua S Agranat ◽

Yoshihiro Yonekawa

Keyword(s):

Optical Coherence Tomography ◽

Anterior Chamber ◽

Incidental Finding ◽

Pigment Epithelium ◽

Anterior Segment ◽

Ultrasound Biomicroscopy ◽

Optical Coherence ◽

Visual Axis ◽

Associated Malignancy ◽

Anatomic Locations

Iris pigment epithelial (IPE) cysts are a subset of iris cysts that arise from the IPE. They are spontaneously erupting epithelial-lined cavities that are found in various anatomic locations of the iris, including the iris pupillary margin, midzone, periphery, and free floating in the vitreous or anterior chamber. We report the case of an asymptomatic 13-year-old boy with an incidental finding of a dislodged anterior chamber cyst diagnosed on routine examination. Modern multimodal image analysis of the cyst including anterior segment optical coherence tomography and ultrasound biomicroscopy (UBM) was utilized to characterize the microstructural anatomy of the lesion. The patient was managed conservatively without complications. Cysts of the IPE typically do not affect vision or ocular health and can be monitored and observed after ascertaining no associated malignancy. Initial diagnostic investigation can include UBM and anterior segment optical coherence tomography. Intervention should be reserved only for cases where the cyst growth leads to obstruction of the visual axis and/or other secondary complications.

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Objective quantification of lens nuclear opacities using swept-source anterior segment optical coherence tomography

British Journal of Ophthalmology ◽

10.1136/bjophthalmol-2020-318334 ◽

2021 ◽

pp. bjophthalmol-2020-318334

Author(s):

Wei Wang ◽

Jiaqing Zhang ◽

Xiaoxun Gu ◽

Xiaoting Ruan ◽

Xiaoyun Chen ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Visual Acuity ◽

Anterior Segment ◽

Training Dataset ◽

Dissipated Energy ◽

Nuclear Density ◽

Optical Coherence ◽

Nuclear Cataract ◽

Swept Source ◽

Ultrasonic Time

Background/aimsThe primary objective is to quantify the lens nuclear opacity using swept-source anterior segment optical coherence tomography (SS-ASOCT) and to evaluate its correlations with Lens Opacities Classification System III (LOCS-III) system and surgical parameters. The secondary objective is to assess the diagnostic performance for hard nuclear cataract.MethodsThis cross-sectional study included 1222 patients eligible for cataract surgery (1222 eyes). The latest SS-ASOCT (CASIA-2) was used to obtain high-resolution lens images, and the average nuclear density (AND) and maximum nuclear density (MND) were measured by a custom ImageJ software. Spearman’s correlations analysis was used to assess associations of AND/MND with LOCS-III nuclear scores, visual acuity and surgical parameters. The subjects were then split randomly (9:1) into the training dataset and validating dataset. Receiver operating characteristic curves and calibration curves were constructed for the classification on hard nuclear cataract.ResultsThe AND and MND from SS-ASOCT images were significantly correlated with nuclear colour scores (AND: r=0.716; MND: r=0.660; p<0.001) and nuclear opalescence scores (AND: r=0.712; MND: r=0.655; p<0.001). The AND by SS-ASOCT images had the highest values of Spearman’s r for preoperative corrected distance visual acuity (r=0.3131), total ultrasonic time (r=0.3481) and cumulative dissipated energy (r=0.4265). The nuclear density had good performance in classifying hard nuclear cataract, with area under the curves of 0.859 (0.831–0.886) for AND and 0.796 (0.768–0.823) for MND.ConclusionObjective and quantitative evaluation of the lens nuclear density using SS-ASOCT images enable accurate diagnosis of hard nuclear cataract.

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