scholarly journals Serum pharmacokinetics and cerebrospinal fluid concentration analysis of the new IgG4 monoclonal antibody GNbAC1 to treat multiple sclerosis: A Phase 1 study

mAbs ◽  
2016 ◽  
Vol 8 (5) ◽  
pp. 854-860 ◽  
Author(s):  
François Curtin ◽  
Virginie Vidal ◽  
Corinne Bernard ◽  
Arno Kromminga ◽  
Alois B. Lang ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Monoclonal Antibody ◽  
Cerebrospinal Fluid ◽  
Phase 1 ◽  
Phase 1 Study ◽  
Cerebrospinal Fluid Concentration ◽  
Fluid Concentration

BACE1 Inhibitor Lanabecestat (AZD3293) in a Phase 1 Study of Healthy Japanese Subjects: Pharmacokinetics and Effects on Plasma and Cerebrospinal Fluid Aβ Peptides

2017 ◽  
Vol 57 (11) ◽  
pp. 1460-1471 ◽  
Author(s):  
Kei Sakamoto ◽  
Shunji Matsuki ◽  
Kyoko Matsuguma ◽  
Tatsuya Yoshihara ◽  
Naoki Uchida ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Phase 1 ◽  
Phase 1 Study ◽  
Aβ Peptides ◽  
Bace1 Inhibitor ◽  
Japanese Subjects

scholarly journals Phase 1 study of MEDI0562, a humanized OX40 agonist monoclonal antibody (mAb), in adult patients (pts) with advanced solid tumors

2016 ◽  
Vol 27 ◽  
pp. vi361 ◽  
Author(s):  
B.S. Glisson ◽  
R. Leidner ◽  
R.L. Ferris ◽  
J. Powderly ◽  
N. Rizvi ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Solid Tumors ◽  
Phase 1 ◽  
Adult Patients ◽  
Advanced Solid Tumors ◽  
Phase 1 Study

scholarly journals Reduced cerebrospinal fluid concentration of interleukin-12/23 subunit p40 in patients with cognitive impairment

PLoS ONE ◽  
2017 ◽  
Vol 12 (5) ◽  
pp. e0176760 ◽  
Author(s):  
Per Johansson ◽  
Erik G. Almqvist ◽  
Anders Wallin ◽  
Jan-Ove Johansson ◽  
Ulf Andreasson ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Cognitive Impairment ◽  
Interleukin 12 ◽  
Cerebrospinal Fluid Concentration ◽  
Fluid Concentration
Sign in / Sign up

Export Citation Format

Share Document