scholarly journals Arginine-induced metabolomic perturbation in Streptococcus mutans

2022 ◽  
Vol 14 (1) ◽  
Author(s):  
Yudong Liu ◽  
Shanshan Liu ◽  
Qinghui Zhi ◽  
Peilin Zhuang ◽  
Rongxiu Zhang ◽  
...  
Keyword(s):  
Author(s):  
M. J. Kramer ◽  
Alan L. Coykendall

During the almost 50 years since Streptococcus mutans was first suggested as a factor in the etiology of dental caries, a multitude of studies have confirmed the cariogenic potential of this organism. Streptococci have been isolated from human and animal caries on numerous occasions and, with few exceptions, they are not typable by the Lancefield technique but are relatively homogeneous in their biochemical reactions. An analysis of the guanine-cytosine (G-C) composition of the DNA from strains K-1-R, NCTC 10449, and FA-1 by one of us (ALC) revealed significant differences and DNA-DNA reassociation experiments indicated that genetic heterogeneity existed among the three strains. The present electron microscopic study had as its objective the elucidation of any distinguishing morphological characteristics which might further characterize the respective strains.


2019 ◽  
Vol 14 (1) ◽  
pp. 92
Author(s):  
Dr. Maha Abdul- Kareem Mahmood ◽  
Dr. Huda Elias Ali ◽  
Dr. Haraa Khairi Abdul-Kadher

Microbes are considered as the primary etiologic agents in endodontic diseases.Disinfection of the root canal is obtained by the combined effect of biomechanicalpreparation, irrigation and intra canal medicament. The aim of the present study wasto assess the antimicrobial activity of intracanal medicaments (formocresol andEndosepton) against two micro organisms (Streptococcus mutans and staphylococcusaureus) isolated from 15 necrotic pulps of primary molars indicated for pulpectomyprocedure. The samples were cultured, and purified using microbiological evaluation.Broth dilution test was performed in our study by preparing test tubes containing10 ml of BHI broth (pH. 7) which then inoculated with strains of the tested bacteriaand incubated at 37 C° for 24 h. After over night incubaction, ten fold dilution weremade in test tubes containing 9 ml of normal saline by adding 1 ml of the inoculum tothe first tube . Then from dilution 10-1 , 0.1 ml of cell suspension was added to 9.9 mlof formocresol and endosepton, then 0.1 ml was taken and spread on duplicates ofBHI agar plates at different intervals and incubated aerobically for 24 h. at 37 C°.Colonies on the plates were counted after incubation and CFU/mL (colony formingunit) was calculated. Our results indicating that there were no significant differencesbetween the intracanal medicaments, but there were high significant differencesbetween the intervals time of the study. We concluded that both materials had greatantibacterial effect against the pathogens commonly isolated from necrotic pulpaltissue of primary teeth.


2003 ◽  
Author(s):  
Charles Thomas Parker ◽  
Dorothea Taylor ◽  
George M Garrity
Keyword(s):  

2003 ◽  
Author(s):  
Charles Thomas Parker ◽  
Dorothea Taylor ◽  
George M Garrity
Keyword(s):  

2003 ◽  
Author(s):  
Charles Thomas Parker ◽  
Dorothea Taylor ◽  
George M Garrity
Keyword(s):  

2003 ◽  
Author(s):  
Charles Thomas Parker ◽  
Dorothea Taylor ◽  
George M Garrity
Keyword(s):  

2003 ◽  
Author(s):  
Charles Thomas Parker ◽  
Dorothea Taylor ◽  
George M Garrity
Keyword(s):  

2003 ◽  
Author(s):  
Charles Thomas Parker ◽  
Dorothea Taylor ◽  
George M Garrity
Keyword(s):  

Author(s):  
Zuhendi Arifan Siagian ◽  
Habibah Wulandarena Hosaina ◽  
Mellisa Sim

Dewasa ini bahan antibakteri banyak di teliti, baik senyawa kimia ataupun alami untuk menghambat perkembangan bakteri. Ekstrak daun salam (Syzygium polyanthum) dan kitosan nanopartikel banyak menjadi bahan penghambat antibakteri ”Streptococcus mutans” yang adekuat, sehingga banyak peneliti mengembangkan bahan tersebut agar mendapatkan efek maksimal dari bahan antibakterinya. Penelitian ini memiliki tujuan untuk melihat peningkatan efek ekstrak daun salam - Kitosan Nanopartikel 1% terhadap pertumbuhan bakteri Streptococcus mutans. Proses maserasi di lakukan pada ekstrak daun salam kemudian konsentrasinya di ubah menjadi 50%, 75% dan 100%, pencampuran dengan kitosan nanopartikel 1% dengan perbandingan 1:1. Metode uji disc diffusion (Tes Kirby-Bauer) untuk melihat efektifitas antibakteri. Uji statistik one way ANOVA menunjukan angka yang signifikan p>0,05 dengan hasil ekstrak daun salam konsentrasi 100%, 75% dan 50% - kitosan naopartikel 1% dalam menghambat pertumbuhan bakteri Streptococcus mutans adalah 13,45 ± 0,2881 mm, 12,67 ± 0,2733 mm dan 11,52 ± 0,4070 mm. Maka ekstrak daun salam - Kitosan nanopartikel mempunyai efek antibakteri yang kuat terhadap bakteri “Streptococcus mutans” dari setiap grup penelitian yang di lakukan, efek tertinggi konsentrasi ekstrak daun salam 100% - nanopartikel kitosan 1% sebesar 13,45 mm.


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