Safety, reactogenicity and immunogenicity of 2-dose catch-up vaccination with 10-valent pneumococcal non-typeableHaemophilus influenzaeprotein D conjugate vaccine (PHiD-CV) in Malian children in the second year of life: Results from an open study

Abstract Background After successful meningococcal serogroup A conjugate vaccine (MACV) campaigns since 2010, Burkina Faso introduced MACV in March 2017 into the routine Expanded Programme for Immunization schedule at age 15–18 months, concomitantly with second-dose measles-containing vaccine (MCV2). We examined MCV2 coverage in pre- and post-MACV introduction cohorts to describe observed changes regionally and nationally. Methods A nationwide household cluster survey of children 18–41 months of age was conducted 1 year after MACV introduction. Coverage was assessed by verification of vaccination cards or recall. Two age groups were included to compare MCV2 coverage pre-MACV introduction (30–41 months) versus post-MACV introduction (18–26 months). Results In total, 15 925 households were surveyed; 7796 children were enrolled, including 3684 30–41 months of age and 3091 18–26 months of age. Vaccination documentation was observed for 86% of children. The MACV routine coverage was 58% (95% confidence interval [CI], 56%–61%) with variation by region (41%–76%). The MCV2 coverage was 62% (95% CI, 59%–65%) pre-MACV introduction and 67% (95% CI, 64%–69%) post-MACV introduction, an increase of 4.5% (95% CI, 1.3%–7.7%). Among children who received routine MACV and MCV2, 93% (95% CI, 91%–94%) received both at the same visit. Lack of caregiver awareness about the 15- to 18-month visit and vaccine unavailability were common reported barriers to vaccination. Conclusions A small yet significant increase in national MCV2 coverage was observed 1 year post-MACV introduction. The MACV/MCV2 coadministration was common. Findings will help inform strategies to strengthen second-year-of-life immunization coverage, including to address the communication and vaccine availability barriers identified.

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Serotype-Specific Immune Unresponsiveness to Pneumococcal Conjugate Vaccine following Invasive Pneumococcal Disease

Infection and Immunity ◽

10.1128/iai.00796-08 ◽

2008 ◽

Vol 76 (11) ◽

pp. 5305-5309 ◽

Cited By ~ 30

Author(s):

Ray Borrow ◽

Elaine Stanford ◽

Pauline Waight ◽

Matthew Helbert ◽

Paul Balmer ◽

...

Keyword(s):

Conjugate Vaccine ◽

Invasive Pneumococcal Disease ◽

Pneumococcal Disease ◽

Clinical Risk Factor ◽

Total Serum ◽

Cell Wall Polysaccharide ◽

Antibody Testing ◽

Igg Antibody ◽

Second Year Of Life ◽

Second Year

ABSTRACT Following the introduction of the pneumococcal 7-valent conjugate vaccine (PCV7) into the routine infant immunization schedule in England, Wales, and Northern Ireland, pneumococcal serotype-specific immunoglobulin G (IgG) antibody testing was offered as a clinical service to all children within the program with invasive pneumococcal disease (IPD) to confirm an adequate antibody response to PCV7. As of March 2008, serum samples taken within 14 to 90 days of vaccination had been submitted from 107 children who had received one or more doses in the second year of life. Sera were assayed by a multiplexed microsphere assay incorporating both cell wall polysaccharide and serotype 22F adsorption. A protective serotype-specific antibody level was defined as a concentration of ≥0.35 μg/ml. Eight children failed to develop a response to their infecting serotype (6B [n = 4], 18C [n = 2], 4 [n = 1], and 14 [n = 1]), despite receiving at least three doses of PCV7 in the second year of life or two doses in the second and two or three in the first year of life. A further two children were nonresponsive to a serotype (6B) different than that causing disease. None of the 10 children had a clinical risk factor for IPD. Two had marginally low levels of total serum IgG but mounted adequate responses to the other six PCV serotypes. This serotype-specific unresponsiveness may reflect immune paralysis due to large pneumococcal polysaccharide antigen loads and/or a potential genetic basis for nonresponse to individual pneumococcal serotypes.

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DEVELOPMENT OF VLBW PREMATURES IN THE SECOND YEAR OF LIFE

Neuropediatrics ◽

10.1055/s-2006-945619 ◽

2006 ◽

Vol 37 (S 1) ◽

Author(s):

E Rodríguez ◽

M Bellotti ◽

S Liendo ◽

S Napoli ◽

MM Contreras ◽

...

Keyword(s):

Second Year Of Life ◽

Second Year

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Evaluation of Visuospatial Short-term and Working Memory from the First to Second Year of Life: A Novel Task

Developmental Neuropsychology ◽

10.1080/87565641.2020.1869744 ◽

2021 ◽

pp. 1-17

Author(s):

C. Fernandez-Baizan ◽

Miguel Angel Prieto ◽

J. A. Martinez ◽

J. L. Arias ◽

M. Mendez

Keyword(s):

Working Memory ◽

Short Term ◽

Second Year Of Life ◽

Second Year

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Understanding Interest in the Second Year of Life

Infancy ◽

10.1111/j.1532-7078.2009.00011.x ◽

2010 ◽

Vol 15 (3) ◽

pp. 324-335 ◽

Cited By ~ 1

Author(s):

Amy C. MacPherson ◽

Chris Moore

Keyword(s):

Second Year Of Life ◽

Second Year

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Longitudinal trajectories of gestural and linguistic abilities in very preterm infants in the second year of life

Neuropsychologia ◽

10.1016/j.neuropsychologia.2011.09.023 ◽

2011 ◽

Vol 49 (13) ◽

pp. 3677-3688 ◽

Cited By ~ 60

Author(s):

Alessandra Sansavini ◽

Annalisa Guarini ◽

Silvia Savini ◽

Serena Broccoli ◽

Laura Justice ◽

...

Keyword(s):

Preterm Infants ◽

Very Preterm Infants ◽

Very Preterm ◽

Longitudinal Trajectories ◽

Second Year Of Life ◽

Second Year

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Life cycle of the western school prawn, Metapenaeus dalli Racek, in a Western Australian estuary

Marine and Freshwater Research ◽

10.1071/mf9860095 ◽

1986 ◽

Vol 37 (1) ◽

pp. 95 ◽

Cited By ~ 19

Author(s):

IC Potter ◽

JW Penn ◽

KS Brooker

Keyword(s):

Life Cycle ◽

Western Australia ◽

Sexual Maturity ◽

Second Year Of Life ◽

Second Year ◽

Australian Estuary ◽

Western Australian

The absence of marine records for M. dalli below latitude 31�S., together with data on gonadal stages and spermatophore deposition on females of this species in the Swan estuary, provide very strong indications that the western school prawn typically breeds in estuarine environments in south-western Australia. The 0 + recruits, which first appeared in samples in February, remained in the estuary during the following months and by November had reached a size suitable for exploitation. At this time they were approaching sexual maturity and were starting to move from the shallows to the deeper waters of the estuary where they remained for their second year of life. In contrast to Australian Penaeus species, M. dalli mates during the intermoult period when the shell is hard rather than immediately after moulting.

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Supplementary Checks on the Scales of Pink Salmon (Oncorhynchus gorbuscha) and Chum Salmon (O. keta)

Journal of the Fisheries Research Board of Canada ◽

10.1139/f65-127 ◽

1965 ◽

Vol 22 (6) ◽

pp. 1477-1489 ◽

Cited By ~ 14

Author(s):

H. T. Bilton ◽

W. E. Ricker

Keyword(s):

British Columbia ◽

Chum Salmon ◽

Pink Salmon ◽

Oncorhynchus Gorbuscha ◽

Commercial Fisheries ◽

Pink Salmon Oncorhynchus Gorbuscha ◽

Clear Cut ◽

Second Year Of Life ◽

Second Year ◽

Similar Incidence

Among 159 central British Columbia pink salmon that had been marked by removal of two fins as fry and had been recovered in commercial fisheries after one winter in the sea, the scales of about one-third showed a supplementary or "false" check near the centre of the scale, in addition to the single clear-cut annulus. This evidence from fish of known age confirms the prevailing opinion that such extra checks do not represent annuli, hence that the fish bearing them are in their second year of life rather than their third. Unmarked pink salmon from the same area, and some from southern British Columbia, had a generally similar incidence of supplementary checks. In both marked and unmarked fish the supplementary checks varied in distinctness from faint to quite clear. In a sample of scales of 14 double-fin marked chum salmon which were known to be in their 4th year, all fish had the expected 3 annuli, and 12 fish had a supplementary check inside the first annulus.

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