Therapeutic potential of GABAA receptor subunit expression abnormalities in fragile X syndrome

2022 ◽  
pp. 1-16
Author(s):  
Mathijs B. van der Lei ◽  
R. Frank Kooy
Keyword(s):  
Fragile X Syndrome ◽  
Gabaa Receptor ◽  
Therapeutic Potential ◽  
Fragile X ◽  
Receptor Subunit ◽  
Subunit Expression

scholarly journals The GABAA receptor is an FMRP target with therapeutic potential in fragile X syndrome

Cell Cycle ◽  
2015 ◽  
Vol 14 (18) ◽  
pp. 2985-2995 ◽  
Author(s):  
Sien Braat ◽  
Charlotte D'Hulst ◽  
Inge Heulens ◽  
Silvia De Rubeis ◽  
Edwin Mientjes ◽  
...  
Keyword(s):  
Fragile X Syndrome ◽  
Gabaa Receptor ◽  
Therapeutic Potential ◽  
Fragile X

Heterogeneous GABAA receptor subunit expression in pediatric epilepsy patients

2005 ◽  
Vol 18 (3) ◽  
pp. 484-491 ◽  
Author(s):  
Brenda E. Porter ◽  
Guojun Zhang ◽  
Juanita Celix ◽  
Fu-chun Hsu ◽  
YogendraSinh H. Raol ◽  
...  
Keyword(s):  
Gabaa Receptor ◽  
Pediatric Epilepsy ◽  
Receptor Subunit ◽  
Subunit Expression

scholarly journals Potential role for histone deacetylation in chronic diazepam-induced downregulation of α1-GABAA receptor subunit expression

2018 ◽  
Vol 6 (4) ◽  
pp. e00416 ◽  
Author(s):  
James Auta ◽  
Eleonora Gatta ◽  
John M. Davis ◽  
Subhash C. Pandey ◽  
Alessandro Guidotti
Keyword(s):  
Gabaa Receptor ◽  
Potential Role ◽  
Histone Deacetylation ◽  
Receptor Subunit ◽  
Subunit Expression ◽  
Chronic Diazepam

Expression profiling suggests underexpression of the GABAA receptor subunit δ in the fragile X knockout mouse model

2006 ◽  
Vol 21 (2) ◽  
pp. 346-357 ◽  
Author(s):  
Ilse Gantois ◽  
Jo Vandesompele ◽  
Frank Speleman ◽  
Edwin Reyniers ◽  
Rudi D'Hooge ◽  
...  
Keyword(s):  
Mouse Model ◽  
Gabaa Receptor ◽  
Expression Profiling ◽  
Knockout Mouse ◽  
Fragile X ◽  
Receptor Subunit ◽  
Knockout Mouse Model

Tolerance to diazepam and changes in GABAA receptor subunit expression in rat neocortical areas

Neuroscience ◽  
1997 ◽  
Vol 79 (2) ◽  
pp. 477-487 ◽  
Author(s):  
C Pesold ◽  
H.J Caruncho ◽  
F Impagnatiello ◽  
M.J Berg ◽  
J.-M Fritschy ◽  
...  
Keyword(s):  
Gabaa Receptor ◽  
Receptor Subunit ◽  
Subunit Expression

GABAA receptor subunit expression and assembly in cultured rat cerebellar granule neurons

1996 ◽  
Vol 97 (2) ◽  
pp. 216-225 ◽  
Author(s):  
Laurie S. Nadler ◽  
Lori T. Raetzman ◽  
Kristin L. Dunkle ◽  
Nancy Mueller ◽  
Ruth E. Siegel
Keyword(s):  
Gabaa Receptor ◽  
Cerebellar Granule Neurons ◽  
Granule Neurons ◽  
Receptor Subunit ◽  
Cerebellar Granule ◽  
Subunit Expression
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