Recurrence in long-term survivor of anti-MDA5 antibody-positive clinically amyopathic dermatomyositis: case series and literature review

Abstract Background Growth hormone (GH)-secreting pituitary adenomas represent an uncommon subset of pituitary neoplasms. Stereotactic radiosurgery (SRS) and fractionated stereotactic radiotherapy (FSRT) have been used as primary or adjuvant treatment. The purpose of this study is to report the long-term tumor control and toxicity from our institution and to perform a systematic literature review of acromegaly patients treated with FSRT. Methods We retrospectively reviewed all patients treated with FSRT (median dose 50.4 Gray [Gy], range 50.4–54 Gy) between 2005 and 2012 who had: 1) GH-secreting adenoma with persistently elevated insulin growth factor-1 (IGF-1) despite medical therapy and 2) clinical follow up >3 years after FSRT. Patients were treated with modern FSRT planning techniques. Biochemical control was defined as IGF-1 normalization. Systematic review of the literature was performed for FSRT in acromegaly. Results With a median follow-up of 80 months, radiographic control was achieved in all 11 patients and overall survival was 100%. Long-term biochemical control was achieved in 10 patients (90.9%) with either FSRT alone (36.4%) or FSRT with continued medical management (45.5%). No patient experienced new hypopituitarism, cranial nerve dysfunctions, or visual deficits. Our systematic review found published rates of biochemical control and hypopituitarism vary, with uniformly good radiographic control and low incidence of visual changes. Conclusions Adjuvant FSRT offered effective long-term biochemical control and radiographic control, and there was a lower rate of complications in this current series. Review of the literature shows variations in published rates of biochemical control after FSRT for acromegaly, but low incidence of serious toxicities.

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Corrigendum to “Identifying predictive factors for long-term complications following button battery impactions: A case series and literature review” [Int. J. Pediatr. Otorhinolaryngol. (2016) 198–202]

International Journal of Pediatric Otorhinolaryngology ◽

10.1016/j.ijporl.2016.07.015 ◽

2016 ◽

Vol 88 ◽

pp. 189 ◽

Cited By ~ 1

Author(s):

Michael J. Eliason ◽

Jonathan M. Melzer ◽

Jessica R. Winters ◽

Thomas Q. Gallagher

Keyword(s):

Literature Review ◽

Predictive Factors ◽

Case Series ◽

Button Battery

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PNR-28PRIMARY DISSEMINATED LEPTOMENINGEAL NEUROECTODERMAL TUMORS IN CHILDREN: A CASE SERIES AND REPORT OF A LONG TERM SURVIVOR

Neuro-Oncology ◽

10.1093/neuonc/now067.24 ◽

2016 ◽

Vol 18 (suppl 3) ◽

pp. iii12.2-iii12

Author(s):

Amanda Li ◽

Christopher Dunham ◽

Sylvia Cheng

Keyword(s):

Case Series ◽

Neuroectodermal Tumors ◽

Term Survivor

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Stability of unilateral sagittal split ramus osteotomy for correction of facial asymmetry: long-term case series and literature review

Journal of the Korean Association of Oral and Maxillofacial Surgeons ◽

10.5125/jkaoms.2015.41.3.156 ◽

2015 ◽

Vol 41 (3) ◽

pp. 156 ◽

Cited By ~ 7

Author(s):

Seong-Geun Lee ◽

Young-Hoon Kang ◽

June-Ho Byun ◽

Uk-Kyu Kim ◽

Jong-Ryoul Kim ◽

...

Keyword(s):

Literature Review ◽

Case Series ◽

Facial Asymmetry ◽

Sagittal Split Ramus Osteotomy

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Triple Atresia, Triple Threat? An Unusual Constellation of Primary Surgical Abnormalities

Pediatric Reports ◽

10.3390/pediatric13020026 ◽

2021 ◽

Vol 13 (2) ◽

pp. 189-196

Author(s):

Raef Jackson ◽

Carmen Francis ◽

Karim Awad ◽

Semiu E. Folaranmi

Keyword(s):

Literature Review ◽

Neonatal Period ◽

Oesophageal Atresia ◽

Case Series ◽

Duodenal Atresia ◽

Vacterl Association ◽

Term Survival ◽

Staged Approach ◽

Definitive Surgery

We present a case series of two patients with tracheo-oesophageal fistula with oesophageal atresia (TOF/OA), duodenal atresia (DA) and ano-rectal malformation (ARM). This constellation of abnormalities, dubbed triple atresia (TA), is a rare combination with few described cases in the literature. Here we describe our management of these cases, as well as the results of our literature review. Both of our cases had staged surgical procedures and were initially managed with thoracotomy for repair of TOF/OA on day two of life. They subsequently underwent laparotomy for management of their abdominal pathology at day five and seven of life. Both have survived the neonatal period and are awaiting definitive surgery for ARM. Literature review yielded seven cases of TA involving a TOF, DA, and ARM. Four patients underwent staged repair, while three patients underwent repair of TOF/OA, DA and colostomy for ARM at the same time. Of these three patients, two died, representing 22% of the overall cohort. Triple atresia remains a rare subset of patients suspected to have VACTERL association, however mortality may be significantly higher. Our data would suggest a staged approach to be optimal for long term survival.

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