Natural killer cell granules converge to avoid collateral damage
2016 ◽
Vol 215
(6)
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pp. 765-767
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Keyword(s):
To clear infection, cytotoxic lymphocytes must destroy target cells while avoiding nonspecific killing of surrounding healthy cells. In this issue, Hsu et al. (2016. J. Cell Biol. https://doi.org/10.1083/jcb.201604136) use live-cell imaging to show that lytic granule convergence protects bystander cells from unintended death by promoting polarized secretion of soluble cytolytic proteins toward the intended target.
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2013 ◽
Vol 174
(3)
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pp. 414-423
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Keyword(s):
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1993 ◽
Vol 161
(1)
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pp. 135-137
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1990 ◽
Vol 6
(7)
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pp. 905-918
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2018 ◽
Vol 142
(4)
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pp. 1311-1321.e8
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1985 ◽
Vol 82
(16)
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pp. 5578-5578