Separate cytotoxic T lymphocyte subsets recognize the different H-2 specificities.
1980 ◽
Vol 151
(3)
◽
pp. 773-780
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Keyword(s):
Using a monolayer adsorption technique, the fine specificity of cytotoxic effector T lymphocytes (CTL) generated against allogeneic or semi-allogeneic H-2 haplotypes was investigated. The results show that: (a) CTL reacting with the private specificity expressed on an H-2.K molecule can be separated from those reacting with the public specificities expressed on the same molecule and (b) the CTL that recognize cross-reacting H-2 determinants (public specificities) can also be separated into several subpopulations. These data support the hypothesis that an allogeneic stimulation induces a large number of independent T cell clones that react with H-2 determinants.
Keyword(s):
1986 ◽
Vol 163
(6)
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pp. 1583-1588
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Keyword(s):
2007 ◽
Vol 13
(5)
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pp. 1031-1042
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2009 ◽
Vol 1
(4)
◽
pp. 317-321
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Keyword(s):
2008 ◽
Vol 42
(10)
◽
pp. 519-522
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Keyword(s):