Biological and biochemical characterization of a cloned Leu-3- cell surviving infection with the acquired immune deficiency syndrome retrovirus.

Leu-3- cells that survive infection with the acquired immune deficiency syndrome (AIDS) retrovirus can be induced with IUdR to express infectious virus. A cellular clone (8E5), isolated by limiting dilution of a mass culture of survivor cells, was found to contain a single, integrated provirus that was constitutively expressed. Although IUdR treatment of 8E5 cells failed to induce infectious virus, cocultivation with Leu-3+ cells generated the characteristic syncytia associated with acute AIDS retrovirus infection. The single integrated copy of proviral DNA directs the synthesis of all major viral structural proteins except p64, as monitored by immunoblotting. The relationship of the 8E5 clone to viral latency and persistence is discussed.

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Lack of correlation between fulminant form of viral hepatitis and retrovirus infection associated with the acquired immune deficiency syndrome (AIDS) in drug addicts.

BMJ ◽

10.1136/bmj.292.6517.376 ◽

1986 ◽

Vol 292 (6517) ◽

pp. 376-377 ◽

Cited By ~ 5

Author(s):

P Amoroso ◽

G Lettieri ◽

A Giorgio ◽

P Fico ◽

P Pierri ◽

...

Keyword(s):

Immune Deficiency ◽

Viral Hepatitis ◽

Immune Deficiency Syndrome ◽

Acquired Immune Deficiency Syndrome ◽

Deficiency Syndrome ◽

Drug Addicts ◽

Retrovirus Infection ◽

Acquired Immune Deficiency

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Relationship of Knowledge with Readiness to Prevent the Occurrence of HIV / AIDS in Aliyah Guppi Students

Comprehensive Health Care ◽

10.37362/jch.v2i1.242 ◽

2018 ◽

Vol 2 (1) ◽

pp. 40-48

Author(s):

Edison Siringoringo ◽

Amirullah ◽

Nurlinda

Keyword(s):

Immune Deficiency ◽

Human Immunodeficiency Virus ◽

Sampling Method ◽

Immune Deficiency Syndrome ◽

Acquired Immune Deficiency Syndrome ◽

Deficiency Syndrome ◽

Immunodeficiency Virus ◽

Relationship Of ◽

Acquired Immune Deficiency ◽

Hiv Aids

One of the viruses that is currently a concern of the world community, because it is considered very dangerous for the survival of a nation is the Human Immunodeficiency Virus (HIV). HIV is a virus that paralyzes the immune system so that it causes Acquired Immune Deficiency Syndrome (AIDS). AIDS stands for Acquired Immune Deficiency Syndrome is a disease characterized by damage to the body's defense system, so that sufferers are easily attacked by a variety of severe infections and unusual cancers. AIDS is caused by the Human Immunodeficiency Virus (HIV). The research design used in this study was observational analytic that is examining the relationship between variables. With a cross-sectional study approach. The population of all students of Madrasah aliyah guppi gunung Jati. The sampling method in this study uses the Nonprobability Sampling method with the sampling technique was purposive sampling with a total of 48 samples based on the sampling formula from Isaac and Michael. Knowledge about HIV / AIDS from 48 respondents can be seen that the most on good knowledge are as many as 47 (97.9%) respondents. Readiness to prevent the occurrence of HIV / AIDS is the most ready to prevent as many as 45 (93.8%) respondents. There is no relationship of knowledge with readiness to prevent the occurrence of HIV / AIDS from the proposed hypothesis known p of 1,000, when compared with an α value of 0, 05 (1,000> 0.05).

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