A critical study of different Monte Carlo scoring methods of dose average linear-energy-transfer maps calculated in voxelized geometries irradiated with clinical proton beams

2015 ◽  
Vol 60 (7) ◽  
pp. 2645-2669 ◽  
Author(s):  
M A Cortés-Giraldo ◽  
A Carabe
Keyword(s):  
Monte Carlo ◽  
Energy Transfer ◽  
Linear Energy Transfer ◽  
Critical Study ◽  
Scoring Methods ◽  
Proton Beams ◽  
Transfer Maps

scholarly journals Standardizing Monte Carlo simulation parameters for a reproducible dose-averaged linear energy transfer

2020 ◽  
Vol 93 (1112) ◽  
pp. 20200122
Author(s):  
Wei Yang Calvin Koh ◽  
Hong Qi Tan ◽  
Khong Wei Ang ◽  
Sung Yong Park ◽  
Wen Siang Lew ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Energy Transfer ◽  
Linear Energy Transfer ◽  
Step Length ◽  
Scoring Methods ◽  
Scoring Method ◽  
Simulation Protocol ◽  
Biological Effectiveness ◽  
Mc Simulation ◽  
Simulation Parameters

Objective: Dose-averaged linear energy transfer (LETD) is one of the factors which determines relative biological effectiveness (RBE) for treatment planning in proton therapy. It is usually determined from Monte Carlo (MC) simulation. However, no standard simulation protocols were established for sampling of LETD. Simulation parameters like maximum step length and range cut will affect secondary electrons production and have an impact on the accuracy of dose distribution and LETD. We aim to show how different combinations of step length and range cut in GEANT4 will affect the result in sampling of LETD using different MC scoring methods. Methods: In this work, different step length and range cut value in a clinically relevant voxel geometry were used for comparison. Different LETD scoring methods were established and the concept of covariance between energy deposition per step and step length is used to explain the differences between them. Results: We recommend a maximum step length of 0.05 mm and a range cut of 0.01 mm in MC simulation as this yields the most consistent LETD value across different scoring methods. Different LETD scoring methods are also compared and variation up to 200% can be observed at the plateau of 80 MeV proton beam. Scoring Method one has one of the lowest percentage differences compared across all simulation parameters. Conclusion: We have determined a set of maximum step length and range cut parameters to be used for LETD scoring in a 1 mm voxelized geometry. LETD scoring method should also be clearly defined and standardized to facilitate cross-institutional studies. Advances in knowledge: Establishing a standard simulation protocol for sampling LETD would reduce the discrepancy when comparing data across different centres, and this can improve the calculation for RBE.

Low-linear energy transfer radiolysis of liquid water at elevated temperatures up to 350°C: Monte-Carlo simulations

2011 ◽  
Vol 508 (4-6) ◽  
pp. 224-230 ◽  
Author(s):  
S. Sanguanmith ◽  
Y. Muroya ◽  
J. Meesungnoen ◽  
M. Lin ◽  
Y. Katsumura ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Energy Transfer ◽  
Monte Carlo Simulations ◽  
Liquid Water ◽  
Linear Energy Transfer ◽  
Elevated Temperatures

PH-0319 Alanine dosimeters for determining linear energy transfer in proton beams

2021 ◽  
Vol 161 ◽  
pp. S228-S229
Author(s):  
R. Nattudurai ◽  
D. Arous ◽  
N.F.J. Edin ◽  
E. Malinen
Keyword(s):  
Energy Transfer ◽  
Linear Energy Transfer ◽  
Proton Beams

Yields of H2 and hydrated electrons in low-LET radiolysis of water determined by Monte Carlo track chemistry simulations using phenol/N2O aqueous solutions up to 350 °C

RSC Advances ◽  
2015 ◽  
Vol 5 (94) ◽  
pp. 76813-76824 ◽  
Author(s):  
Jintana Meesungnoen ◽  
Sunuchakan Sanguanmith ◽  
Jean-Paul Jay-Gerin
Keyword(s):  
Monte Carlo ◽  
Energy Transfer ◽  
Aqueous Solutions ◽  
Linear Energy Transfer ◽  
Effect Of Temperature ◽  
Hydrated Electrons

The effect of temperature on the yields of H2 and hydrated electrons in the low linear energy transfer radiolysis of water has been modeled by Monte Carlo track chemistry simulations using phenol/N2O aqueous solutions from 25 up to 350 °C.

MO-F-214-06: Linear Energy Transfer Response of Polymer Gel Dosimeters in Therapeutic Proton Beams

2011 ◽  
Vol 38 (6Part26) ◽  
pp. 3726-3726
Author(s):  
M Maryanski ◽  
O Lopatiuk-Tirpak ◽  
Z Su ◽  
Z Li ◽  
O Zeidan ◽  
...  
Keyword(s):  
Energy Transfer ◽  
Linear Energy Transfer ◽  
Polymer Gel ◽  
Proton Beams

Yields of primary species in the low-linear energy transfer radiolysis of water in the temperature range of 25–700 °C

2020 ◽  
Vol 22 (14) ◽  
pp. 7430-7439
Author(s):  
Abida Sultana ◽  
Jintana Meesungnoen ◽  
Jean-Paul Jay-Gerin
Keyword(s):  
Monte Carlo ◽  
Energy Transfer ◽  
Linear Energy Transfer ◽  
Water Radiolysis ◽  
Temperature Range

Monte Carlo track chemistry simulations were used to calculate the yields (G values) for the radical (eaq−, H˙, ˙OH) and molecular (H2, H2O2) species formed in low-LET water radiolysis from ∼1 ps to 1 ms between 25 and 700 °C, at 25 MPa pressure.

Acid spike effect in spurs/tracks of the low/high linear energy transfer radiolysis of water: potential implications for radiobiology

RSC Advances ◽  
2015 ◽  
Vol 5 (54) ◽  
pp. 43361-43370 ◽  
Author(s):  
Vanaja Kanike ◽  
Jintana Meesungnoen ◽  
Jean-Paul Jay-Gerin
Keyword(s):  
Monte Carlo ◽  
Energy Transfer ◽  
Water Potential ◽  
Linear Energy Transfer ◽  
Hydronium Ions ◽  
High Linear Energy Transfer

Monte Carlo track chemistry simulations have been used to calculate the yields of hydronium ions that are formed within spurs/tracks of the low/high linear energy transfer radiolysis of pure, deaerated water during and shortly after irradiation.

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