An in vivo area meter for real-time measurement of cross-sectional area in the cardiovascular system

1991 ◽  
Vol 12 (3) ◽  
pp. 253-260 ◽  
Author(s):  
K Tamiya ◽  
M Higashidate ◽  
T Beppu
2021 ◽  
Vol 10 (12) ◽  
pp. 2721
Author(s):  
Nobuto Nakanishi ◽  
Shigeaki Inoue ◽  
Rie Tsutsumi ◽  
Yusuke Akimoto ◽  
Yuko Ono ◽  
...  

Ultrasound has become widely used as a means to measure the rectus femoris muscle in the acute and chronic phases of critical illness. Despite its noninvasiveness and accessibility, its accuracy highly depends on the skills of the technician. However, few ultrasound phantoms for the confirmation of its accuracy or to improve technical skills exist. In this study, the authors created a novel phantom model and used it for investigating the accuracy of measurements and for training. Study 1 investigated how various conditions affect ultrasound measurements such as thickness, cross-sectional area, and echogenicity. Study 2 investigated if the phantom can be used for the training of various health care providers in vitro and in vivo. Study 1 showed that thickness, cross-sectional area, and echogenicity were affected by probe compression strength, probe angle, phantom compression, and varying equipment. Study 2 in vitro showed that using the phantom for training improved the accuracy of the measurements taken within the phantom, and Study 2 in vivo showed the phantom training had a short-term effect on improving the measurement accuracy in a human volunteer. The new ultrasound phantom model revealed that various conditions affected ultrasound measurements, and phantom training improved the measurement accuracy.


2005 ◽  
Vol 5 (1) ◽  
pp. 85-94 ◽  
Author(s):  
Eric H. Ledet ◽  
Michael P. Tymeson ◽  
Darryl J. DiRisio ◽  
Benjamin Cohen ◽  
Richard L. Uhl

2002 ◽  
Vol 282 (5) ◽  
pp. H1697-H1702 ◽  
Author(s):  
Hui Di Wang ◽  
Douglas G. Johns ◽  
Shanqin Xu ◽  
Richard A. Cohen

Our purpose was to address the role of NAPDH oxidase-derived superoxide anion in the vascular response to ANG II. Blood pressure, aortic superoxide anion, 3-nitrotyrosine, and medial cross-sectional area were compared in wild-type mice and in mice that overexpress human superoxide dismutase (hSOD). The pressor response to ANG II was significantly less in hSOD mice. Superoxide anion levels were increased twofold in ANG II-treated wild-type mice but not in hSOD mice. 3-Nitrotyrosine increased in aortic endothelium and adventitia in wild-type but not hSOD mice. In contrast, aortic medial cross-sectional area increased 50% with ANG II in hSOD mice, comparable to wild-type mice. The lower pressor response to ANG II in the mice expressing hSOD is consistent with a pressor role of superoxide anion in wild-type mice, most likely because it reacts with nitric oxide. Despite preventing the increase in superoxide anion and 3-nitrotyrosine, the aortic hypertrophic response to ANG II in vivo was unaffected by hSOD.


1984 ◽  
Vol 57 (5) ◽  
pp. 1399-1403 ◽  
Author(s):  
J. D. MacDougall ◽  
D. G. Sale ◽  
S. E. Alway ◽  
J. R. Sutton

Muscle fiber numbers were estimated in vivo in biceps brachii in 5 elite male bodybuilders, 7 intermediate caliber bodybuilders, and 13 age-matched controls. Mean fiber area and collagen volume density were calculated from needle biopsies and muscle cross-sectional area by computerized tomographic scanning. Contralateral measurements in a subsample of seven subjects indicated the method for estimation of fiber numbers to have adequate reliability. There was a wide interindividual range for fiber numbers in biceps (172,085–418,884), but despite large differences in muscle size both bodybuilder groups possessed the same number of muscle fibers as the group of untrained controls. Although there was a high correlation between average cross-sectional fiber area and total muscle cross-sectional area within each group, many of the subjects with the largest muscles also tended to have a large number of fibers. Since there were equally well-trained subjects with fewer than normal fiber numbers, we interpret this finding to be due to genetic endowment rather than to training-induced hyperplasia. The proportion of muscle comprised of connective and other noncontractile tissue was the same for all subjects (approximately 13%), thus indicating greater absolute amounts of connective tissue in the trained subjects. We conclude that in humans, heavy resistance training directed toward achieving maximum size in skeletal muscle does not result in an increase in fiber numbers.


Sensors ◽  
2008 ◽  
Vol 8 (8) ◽  
pp. 5023-5036 ◽  
Author(s):  
Kate Wassum ◽  
Vanessa Tolosa ◽  
Jianjun Wang ◽  
Eric Walker ◽  
Harold Monbouquette ◽  
...  

1962 ◽  
Vol 202 (5) ◽  
pp. 824-826 ◽  
Author(s):  
Einar Helander ◽  
Carl-Axel Thulin

Isometric tension in tetanically stimulated calf muscles was examined in vivo in 3 rabbits and 18 cats. In two cats the gastrocnemius and soleus muscles were studied separately. After determination of the isometric tension the muscles were dissected and their water content, total N content, and protein composition were analyzed. On this basis it was possible to calculate that part of the cross-sectional area of the muscle fibers which consisted of myofilaments. The recorded maximum isometric tension was related to the myofilamental cross-sectional area. Under the given experimental conditions, the calf muscles developed a tension of 108 ± 5 g/mm2 cross-sectional area. Higher values resulted from tests of individual calf muscles than from combined muscles.


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