Cerebral critical closing pressure estimation from Finapres and arterial blood pressure measurements in the aorta

Critical closing pressure (CCP) is an arterial pressure threshold below which small arterial vessels collapse. Our aim was to compare different methods to estimate CCP in the cerebrovascular circulation using the relationships between transcranial Doppler flow velocity (FV), laser-Doppler flux (LDF), and arterial blood pressure (ABP). A total of 116 experiments in rabbits were analyzed retrospectively. At the end of each recording, cardiac arrest (CA) was induced. Arterial blood pressure in femoral artery, basilar artery FV, cortical blood LDF, intracranial pressure (ICP) was recorded. Critical closing pressure was estimated using linear regression between decreasing mean ABP values, FV, and LDF during CA. In addition, CCP was calculated from FV waveform just before CA. The correlation between CCP evaluated using LDF and FV during CA was 0.98 ( P < 0.0001). The correlation between CCP measured during CA and CCP estimated from the transcranial Doppler ultrasonography (TCD) waveform was weaker ( R=0.39; P <0.001), with CCP calculated from waveform being significantly greater than CCP from CA (median difference 9 mm Hg; P < 0.003). Critical closing pressures obtained from FV waveform and CA correlated with mean ICP before CA ( R = 0.40; P = 0.001). In conclusion strong correlation exists between CCP values obtained by means of FV and LDF during cardiac arrest. However, predictions of CCP using TCD waveform analysis show substantial differences from values of CCP recorded during cardiac arrest.

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An approach to early stage detection of atherosclerosis using arterial blood pressure measurements

Biomedical Signal Processing and Control ◽

10.1016/j.bspc.2021.102594 ◽

2021 ◽

Vol 68 ◽

pp. 102594

Author(s):

Karan Jain ◽

Suchi Jain ◽

Arijit Guha ◽

Amit Patra

Keyword(s):

Blood Pressure ◽

Arterial Blood Pressure ◽

Early Stage ◽

Pressure Measurements ◽

Arterial Blood

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Direct Arterial Blood Pressure Measurements-Reply

JAMA ◽

10.1001/jama.1981.03320160012012 ◽

1981 ◽

Vol 246 (16) ◽

pp. 1770

Author(s):

Elemer K. Zsigmond

Keyword(s):

Blood Pressure ◽

Arterial Blood Pressure ◽

Pressure Measurements ◽

Arterial Blood ◽

Direct Arterial Blood Pressure

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Assessment of the Antihypertensive Effect of Atenolol with 24 H Ambulatory Monitoring of Blood Pressure

Clinical Science ◽

10.1042/cs057387s ◽

1979 ◽

Vol 57 (s5) ◽

pp. 387s-389s ◽

Cited By ~ 15

Author(s):

J. S. Floras ◽

P. Fox ◽

M. O. Hassan ◽

J. V. Jones ◽

P. Sleight ◽

...

Keyword(s):

Blood Pressure ◽

Essential Hypertension ◽

Arterial Blood Pressure ◽

Antihypertensive Effect ◽

Ambulatory Monitoring ◽

Single Daily Dose ◽

Pressure Measurements ◽

Arterial Blood ◽

Blood Pressure Study ◽

Daily Dose

1. Twenty-four hour intra-arterial blood pressure measurements and electrocardiograms were obtained from 12 subjects with untreated essential hypertension. 2. The patients kept records of their activity, paying particular attention to times of retiring to bed, and times of waking in the morning. 3. All subjects were treated with a single daily dose of atenolol (50 to 200 mg) for between 2 and 9 months, and then underwent a second 24 h blood pressure study. 4. Arterial blood pressure was lowered significantly throughout the 24 h period with a single daily dose of atenolol.

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Intra-arterial blood pressure measurements

JAMA ◽

10.1001/jama.245.7.703b ◽

1981 ◽

Vol 245 (7) ◽

pp. 703b-703

Author(s):

E. K. Zsigmond

Keyword(s):

Blood Pressure ◽

Arterial Blood Pressure ◽

Pressure Measurements ◽

Arterial Blood

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Comparison of simultaneous measurement of mouse systolic arterial blood pressure by radiotelemetry and tail-cuff methods

AJP Heart and Circulatory Physiology ◽

10.1152/ajpheart.01089.2003 ◽

2004 ◽

Vol 286 (6) ◽

pp. H2408-H2415 ◽

Cited By ~ 142

Author(s):

Steven E. Whitesall ◽

Janet B. Hoff ◽

Alan P. Vollmer ◽

Louis G. D'Alecy

Keyword(s):

Blood Pressure ◽

Linear Regression ◽

Arterial Blood Pressure ◽

Systolic Pressure ◽

Pressure Measurements ◽

Mouse Blood ◽

Initial Flow ◽

Arterial Blood ◽

Systolic Arterial Blood Pressure ◽

Tail Cuff

Radiotelemetry of mouse blood pressure accurately monitors systolic pressure, diastolic pressure, heart rate, and locomotor activity but requires surgical implantation. Noninvasive measurements of indirect systolic blood pressure have long been available for larger rodents and now are being reported more frequently for mice. This study compared mouse systolic arterial blood pressure measurements using implanted radiotelemetry pressure transducer with simultaneous tail-cuff measurements in the same unanesthetized mice. The pressure range for comparison was extended by inducing experimental hypertension or by observations of circadian elevations between 3 AM and 6 AM. Both trained and untrained tail-cuff operators used both instruments. Every effort was made to follow recommended manufacturer's instructions. With the initial flow-based tail-cuff instrument, we made 671 comparisons (89 sessions) and found the slope of the linear regression to be 0.118, suggesting poor agreement. In an independent assessment, 277 comparisons (35 sessions) of radiotelemetry measurements with the pulse based tail-cuff instrument were made. The slope of the linear regression of the simultaneous measurements of systolic pressures was 0.98, suggesting agreement. Bland-Altman analysis also supported our interpretation of the linear regression. Thus although reliable systolic pressure measurements are possible with either tail-cuff or radiotelemetry techniques, in our hands some tail-cuff instruments fail to accurately detect elevated blood pressures. These data, however, do not distinguish whether this instrument-specific tail-cuff failure was due to operator or instrument inadequacies. We strongly advise investigators to obtain an independent and simultaneous validation of tail-cuff determinations of mouse blood pressure before making critical genotyping determinations.

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Indirect Arterial Blood Pressure Measurement in Nonsedated Irish Wolfhounds: Reference Values for the Breed

Journal of the American Animal Hospital Association ◽

10.5326/0380521 ◽

2002 ◽

Vol 38 (6) ◽

pp. 521-526 ◽

Cited By ~ 11

Author(s):

Janice M. Bright ◽

Mariellen Dentino

Keyword(s):

Blood Pressure ◽

Arterial Blood Pressure ◽

Reference Values ◽

Diastolic Pressure ◽

Blood Pressure Measurement ◽

Systolic Pressure ◽

Standing Position ◽

Mean Value ◽

Pressure Measurements ◽

Arterial Blood

Arterial blood pressure measurements were obtained from 158 healthy Irish wolfhounds using the oscillometric technique to establish reference values for the breed. In contrast to other sight hounds, Irish wolfhounds have low arterial blood pressure. Mean systolic pressure for the group was 116.0 mm Hg. Mean diastolic pressure was 69.2 mm Hg, and the mean value for mean arterial pressure was 87.8 mm Hg. Blood pressure measurements were higher in older wolfhounds than in young dogs. There was no difference between systolic and mean arterial blood pressures in lateral recumbency compared to standing position. However, diastolic pressure was slightly lower when standing. Calm dogs had lower pressure than anxious wolfhounds. There was a significant interaction between the effects of age, gender, and mood on systolic, diastolic, and mean arterial blood pressure values.

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