Development and validation of a 3D-printed neuronavigation headset for therapeutic brain stimulation

Abstract Background The role of simulation training in paediatric surgery is expanding as more simulation devices are designed and validated. We aimed to conduct a training needs assessment of UK paediatric surgical trainees to prioritise procedures for simulation, and to validate a novel 3D-printed simulation model for oesophageal atresia and tracheo-oesophageal fistula (OA-TOF) repair. Methods A questionnaire was sent to UK trainee paediatric surgeons surveying the availability and utility of simulation. The operation ranked as most useful to simulate was OA-TOF repair. 3D-printing techniques were used to build an OA-TOF model. Content, face and construct validity was assessed by 40 paediatric surgeons of varying experience. Results Thirty-four paediatric surgeons completed the survey; 79% had access to surgical simulation at least monthly, and 47% had access to paediatric-specific resources. Perceived utility of simulation was 4.1/5. Validation of open OA-TOF repair was conducted by 40 surgeons. Participants rated the model as useful 4.9/5. Anatomical realism was scored 4.2/5 and surgical realism 3.9/5. The model was able to discriminate between experienced and inexperienced surgeons. Conclusion UK paediatric surgeons voted OA-TOF repair as the most useful procedure to simulate. In response we have developed and validated an affordable 3D-printed simulation model for open OA-TOF repair.

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Development and validation of the deep brain stimulation impairment scale (DBS-IS)

Parkinsonism & Related Disorders ◽

10.1016/j.parkreldis.2017.01.002 ◽

2017 ◽

Vol 36 ◽

pp. 69-75 ◽

Cited By ~ 4

Author(s):

Franziska Maier ◽

Catharine J. Lewis ◽

Carsten Eggers ◽

Andrea A. Kühn ◽

Henriette Krug ◽

...

Keyword(s):

Deep Brain Stimulation ◽

Brain Stimulation ◽

Development And Validation ◽

Deep Brain

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Design and clinical validation of a 3D-printed nasopharyngeal swab for COVID-19 testing

10.1101/2020.06.18.20134791 ◽

2020 ◽

Cited By ~ 1

Author(s):

Joshua K Tay ◽

Gail B Cross ◽

Chun Kiat Lee ◽

Benedict Yan ◽

Jerold Loh ◽

...

Keyword(s):

Ex Vivo ◽

Nasopharyngeal Swab ◽

Clinical Validation ◽

The Novel ◽

Threshold Values ◽

Fluid Absorption ◽

Excellent Correlation ◽

Rt Pcr ◽

3D Printed ◽

Development And Validation

AbstractWe describe the development and validation of a novel 3D-printed nasopharyngeal swab for the identification of SARS-CoV-2. We subjected the novel swab to mechanical and fluid absorption testing ex-vivo, and confirmed its ability to retain and release murine coronavirus and SARS-CoV-2. Compared to the Copan FLOQSwab, the novel swab displayed excellent correlation of RT-PCR cycle threshold values on paired clinical testing in COVID-19 patients, at r = 0.918 and 0.943 for the SARS-CoV-2 ORF1/a and sarbecovirus E-gene respectively. Overall positive and negative percent agreement was 90.6% and 100% respectively on a dual-assay RT-PCR platform, with discordant samples observed only at high cycle thresholds. When carefully designed and tested, 3D-printed swabs are a viable alternative to traditional swabs and will help mitigate strained resources in the escalating COVID-19 pandemic.

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