Stimulus driver for epilepsy seizure suppression with adaptive loading impedance

2011 ◽  
Vol 8 (6) ◽  
pp. 066008 ◽  
Author(s):  
Ming-Dou Ker ◽  
Chun-Yu Lin ◽  
Wei-Ling Chen
2020 ◽  
Vol 13 (2) ◽  
pp. 85-93
Author(s):  
Kinjal Gangar ◽  
Lokesh Kumar Bhatt

One of the most common neurological disorders, which occurs among 1% of the population worldwide, is epilepsy. Therapeutic failure is common with epilepsy and nearly about 30% of patients fall in this category. Seizure suppression should not be the only goal while treating epilepsy but associated comorbidities, which can further worsen the condition, should also be considered. Treatment of such comorbidities such as depression, anxiety, cognition, attention deficit hyperactivity disorder and, various other disorders which co-exist with epilepsy or are caused due to epilepsy should also be treated. Novel targets or the existing targets are needed to be explored for the dual mechanism which can suppress both the disease and the comorbidity. New therapeutic targets such as IDO, nNOS, PAR1, NF-κb are being explored for their role in epilepsy and various comorbidities. This review explores recent therapeutic targets for the treatment of comorbidities associated with epilepsy.


Author(s):  
Wolfgang L�scher ◽  
Ulrich Ebert ◽  
Holger Lehmann ◽  
Christoph Rosenthal ◽  
Guido Nikkhah

2019 ◽  
Vol 101 ◽  
pp. 106737
Author(s):  
Gareth Morris ◽  
Morten Veno ◽  
Cristina Reschke ◽  
Sebastian Bauer ◽  
Yan Yan ◽  
...  

2008 ◽  
Vol 64 (1) ◽  
pp. 81-85 ◽  
Author(s):  
Beatrix S Traa ◽  
Justin D Mulholland ◽  
Shilpa D Kadam ◽  
Michael V Johnston ◽  
Anne M Comi

Sign in / Sign up

Export Citation Format

Share Document