Multi-threshold window discriminator based on SAR logic

2022 ◽  
Vol 17 (01) ◽  
pp. C01042
Author(s):  
J. Jirsa ◽  
M. Marcisovsky ◽  
J. Jakovenko

Abstract The new X-ray imaging detectors allow capturing an X-ray image in various photon energy ranges in one shot. This technique is called X-ray color imaging, and it is becoming a promising method in fields such as medical imaging, computed tomography, and non-destructive material testing. To measure the energy spectrum in one shot, discriminant circuits need to be integrated into the pixel front-end electronics. Several solutions of in-pixel discriminators exist. However, current designs suffer from a low number of discrimination bins and need to adjust each threshold separately, leading to relatively complicated calibration procedures. This work introduces a novel design of a multi-threshold window discriminator based on successive approximation register logic. This circuit realizes in-pixel binning to ten equidistant windows. Two variables are used for tuning the multi-threshold window discriminator: offset of the first window and width of the windows. Setting these parameters allows the user to fulfill the need of the target application.

2021 ◽  
Vol 20 ◽  
pp. 153303382110101
Author(s):  
Thet-Thet Lwin ◽  
Akio Yoneyama ◽  
Hiroko Maruyama ◽  
Tohoru Takeda

Phase-contrast synchrotron-based X-ray imaging using an X-ray interferometer provides high sensitivity and high spatial resolution, and it has the ability to depict the fine morphological structures of biological soft tissues, including tumors. In this study, we quantitatively compared phase-contrast synchrotron-based X-ray computed tomography images and images of histopathological hematoxylin-eosin-stained sections of spontaneously occurring rat testicular tumors that contained different types of cells. The absolute densities measured on the phase-contrast synchrotron-based X-ray computed tomography images correlated well with the densities of the nuclear chromatin in the histological images, thereby demonstrating the ability of phase-contrast synchrotron-based X-ray imaging using an X-ray interferometer to reliably identify the characteristics of cancer cells within solid soft tissue tumors. In addition, 3-dimensional synchrotron-based phase-contrast X-ray computed tomography enables screening for different structures within tumors, such as solid, cystic, and fibrous tissues, and blood clots, from any direction and with a spatial resolution down to 26 μm. Thus, phase-contrast synchrotron-based X-ray imaging using an X-ray interferometer shows potential for being useful in preclinical cancer research by providing the ability to depict the characteristics of tumor cells and by offering 3-dimensional information capabilities.


2014 ◽  
Vol 27 ◽  
pp. 1460135
Author(s):  
CARMEN PAVEL ◽  
FLORIN CONSTANTIN ◽  
COSMIN IOAN SUCIU ◽  
ROXANA BUGOI

X-ray Computed Tomography (CT) is a powerful non-destructive technique that can yield interesting structural information not discernible through visual examination only. This paper presents the results of the CT scans of four objects belonging to the Romanian cultural heritage attributed to the Vinča, Cucuteni and Cruceni-Belegiš cultures. The study was performed with an X-ray tomographic device developed at the Department for Applied Nuclear Physics from Horia Hulubei National Institute for Nuclear Physics and Engineering in Măgurele, Romania. This apparatus was specially designed for archaeometric studies of low-Z artifacts: ceramic, wood, bone. The tomographic investigations revealed the internal configuration of the objects and provided information about the degree to which the previous manipulations affected the archaeological items. Based on the X-ray images resulting from the CT scans, hints about the techniques used in the manufacturing of the artifacts were obtained, as well as some indications useful for conservation/restoration purposes.


2009 ◽  
Vol 56 (3) ◽  
pp. 1448-1453 ◽  
Author(s):  
I. Lima ◽  
J. T. Assis ◽  
C. R. Apoloni ◽  
S. M. F. Mendonca de Souza ◽  
M. E. L. Duarte ◽  
...  

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