Ethylene Glycol and Dimethyl Sulfoxide Combination Reduces Cryoinjuries and Apoptotic Gene Expression in Vitrified Laying Hen Ovary

2017 ◽  
Vol 15 (6) ◽  
pp. 519-528 ◽  
Author(s):  
Reihane Nateghi ◽  
AliReza Alizadeh ◽  
Yousef Jafari Ahangari ◽  
Rouhollah Fathi ◽  
Amir Akhlaghi
Keyword(s):  
Gene Expression ◽  
Ethylene Glycol ◽  
Dimethyl Sulfoxide ◽  
Laying Hen ◽  
Apoptotic Gene

scholarly journals Apoptotic gene expression in potentially fertile and subfertile men

2011 ◽  
Vol 17 (7) ◽  
pp. 415-420 ◽  
Author(s):  
M. C. O. Cavalcanti ◽  
C. Steilmann ◽  
K. Failing ◽  
M. Bergmann ◽  
S. Kliesch ◽  
...  
Keyword(s):  
Gene Expression ◽  
Apoptotic Gene

scholarly journals Serine 574 phosphorylation alters transcriptional programming of FOXO3 by selectively enhancing apoptotic gene expression

2015 ◽  
Vol 23 (4) ◽  
pp. 583-595 ◽  
Author(s):  
Z Li ◽  
J Zhao ◽  
I Tikhanovich ◽  
S Kuravi ◽  
J Helzberg ◽  
...  
Keyword(s):  
Gene Expression ◽  
Apoptotic Gene

cis-5-Cyclooctene-1,2-dione and its Ethylene Ketals

1972 ◽  
Vol 50 (10) ◽  
pp. 1548-1556 ◽  
Author(s):  
Peter Yates ◽  
E. G. Lewars ◽  
P. H. McCabe
Keyword(s):  
Hydrogen Peroxide ◽  
Acetic Anhydride ◽  
Ethylene Glycol ◽  
Dimethyl Sulfoxide

Oxidation of cis-cis-1,5-cyclooctadiene with hydrogen peroxide gives cis-5-cyclooctene-trans-1,2-diol (3) which is converted to cis-5-cyclooctene-1,2-dione (6) on treatment with dimethyl sulfoxide and acetic anhydride. Bromination of 6 is accompanied by transannular bonding to give a dibromo keto ether 9a or b. Ketalization of 6 with ethylene glycol gives a monoketal 11 and two diketals 12 and 13 with 1,3-dioxolane and 1,4-dioxane rings, respectively. Bromination of 12 with bromine or pyridinium perbromide is accompanied by transannular bonding and fission of one of the 1,3-dioxolane rings to give a dibromo monoketal ether 15a (or b). Bromination of 12 with N-bromosuccinimide followed by dehydrobromination gives a cyclooctadiene-1,2-dione diketal 20a (or b).

scholarly journals Maturation of Human Long-lived Plasma Cells Results in Resistance to Apoptosis by Transcriptional and Epigenetic Regulation

2021 ◽  
Author(s):  
Chester J Joyner ◽  
Ariel Ley ◽  
Doan Nguyen ◽  
Muhammad Ali ◽  
Alessia Corrado ◽  
...  
Keyword(s):  
Gene Expression ◽  
Plasma Cells ◽  
The Novel ◽  
Epigenetic Changes ◽  
Apoptosis Pathway ◽  
Apoptotic Gene ◽  
Survival Gene ◽  
Distinct Morphology ◽  
Antibody Secreting Cells

Antibody secreting cells (ASC) circulate after vaccination and migrate to the bone marrow (BM) where a subset known as long-lived plasma cells (LLPC) persist and secrete antibodies for a lifetime. The mechanisms of how circulating ASC become LLPC are not well elucidated. Here, we show that human blood ASCs have distinct morphology, transcriptomes, and epigenetics compared to BM LLPC. LLPC acquire transcriptional and epigenetic changes in the apoptosis pathway to support their survival. Upregulation of pro-survival gene expression accompanies downregulation of pro-apoptotic gene expression in LLPC. While pro-apoptotic gene loci are less accessible, pro-survival gene loci are not always accompanied by accessibility changes. Importantly, we show similar LLPC morphological and transcriptional maturation of blood ASC in response to the novel in vitro BM mimetic. In all, our study demonstrates that blood ASC in the BM microniche must undergo morphological and molecular changes to mature into apoptotic-resistant LLPC.

scholarly journals Mitochondrial levels determine variability in cell death by modulating apoptotic gene expression

2018 ◽  
Vol 9 (1) ◽  
Author(s):  
Silvia Márquez-Jurado ◽  
Juan Díaz-Colunga ◽  
Ricardo Pires das Neves ◽  
Antonio Martinez-Lorente ◽  
Fernando Almazán ◽  
...  
Keyword(s):  
Gene Expression ◽  
Cell Death ◽  
Apoptotic Gene

scholarly journals Apoptotic gene expression in neuropathic pain

2008 ◽  
Author(s):  
Dario Siniscalco ◽  
Catia Giordano ◽  
Carlo Fuccio ◽  
Livio Luongo ◽  
Annalucia Migliozzi ◽  
...  
Keyword(s):  
Gene Expression ◽  
Neuropathic Pain ◽  
Apoptotic Gene
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