Prevalence and Clinical Characteristics of Post-Thrombotic Syndrome in High-Altitude–Induced Deep Vein Thrombosis: Experience of a Single Tertiary Care Center from Real-World Settings

Select patients with acute deep vein thrombosis (DVT) can be managed as outpatients. We sought to conduct a systematic review of real-world studies describing either (1) the clinical characteristics associated with outpatient DVT treatment in all-comers or (2) emergency department (ED) programs designed to facilitate outpatient DVT treatment. MEDLINE and SCOPUS were searched (January 1, 2012, to May 1, 2018) to identify citations meeting the aforementioned criteria. Twenty-one real-world studies were included. The proportion of all-comer patients with DVT managed as outpatients was ≤50% in 11 of 15 studies. With the exception of younger age, no characteristics were consistently associated with outpatient treatment across the 13 studies reporting these characteristics. We identified 8 studies describing ED programs aimed at facilitating DVT outpatient treatment, all of which provided education and included measures to encourage early outpatient follow-up after ED discharge. In conclusion, the proportion of patients with DVT managed as outpatients across real-world studies was low. Several ED programs aimed at facilitating this treatment have been described. It is possible that programs similar to these will increase the proportion of patients with DVT that can be safely managed as outpatients.

Download Full-text

Retrospective cohort study for evaluating the INR monitoring patterns in patients with deep vein thrombosis in daily practice: Analysis of 2010–2013 database of a tertiary care center

Phlebology The Journal of Venous Disease ◽

10.1177/0268355518806117 ◽

2018 ◽

Vol 34 (5) ◽

pp. 317-323

Author(s):

Murat Sargin ◽

Muge Mete Tasdemir ◽

Huseyin Kuplay ◽

Sevinc Bayer Erdogan ◽

Nehir Tandogar ◽

...

Keyword(s):

Deep Vein Thrombosis ◽

Therapeutic Range ◽

Hospital Admissions ◽

Care Center ◽

Tertiary Care ◽

International Normalized Ratio ◽

Ratio Measurement ◽

Vein Thrombosis ◽

Deep Vein

Objective To evaluate the international normalized ratio (INR) monitoring patterns in patients with deep vein thrombosis. Methods Of 32,012 patients with ≥1 outpatient INR measurement and 42,582 patients with confirmed deep vein thrombosis diagnosis registered to our hospital between 1 January 2010 and 31 December 2013, 6720 records were identified to have both deep vein thrombosis and international normalized ratio measurement, and 4.377 out of 6.720 single patient records were determined to be statistically analyzable. Results Median INR measurement frequency was 6.47 times/year and patients had INR levels of 2–3 in 34.3% of follow-up time. Having ≥70% vs. <70% of follow-up time within therapeutic range was associated with lower hospital admission frequency (9.7 vs. 10.3 times/year). Conclusion Our study revealed only one-third of the follow-up time to be spent within therapeutic INR, association of INR therapeutic range with lesser number of hospital admissions and INR monitoring frequency of 6.47 times/year despite lack of stable INR control in most of the deep vein thrombosis patients.

Download Full-text

Diosmin 600 in adjunction to rivaroxaban reduces the risk of post-thrombotic syndrome after femoropopliteal deep vein thrombosis: results of the RIDILOTT DVT study

International Angiology ◽

10.23736/s0392-9590.20.04356-4 ◽

2020 ◽

Vol 39 (5) ◽

Author(s):

Ilya Schastlivtsev ◽

Kirill Lobastov ◽

Victor Barinov ◽

Irina Kanzafarova

Keyword(s):

Deep Vein Thrombosis ◽

Vein Thrombosis ◽

Post Thrombotic Syndrome ◽

Deep Vein

Download Full-text