Antiproliferative Effect of a Prostatic Cell-Derived Activity on the Human Androgen-Dependent Prostatic Carcinoma Cell Line LNCaP

1995 ◽  
Vol 15 (2) ◽  
pp. 179-185 ◽  
Author(s):  
MOHSEN ABOLHASSANI ◽  
J.W. CHIAO
Keyword(s):  
Cell Line ◽  
Prostatic Carcinoma ◽  
Carcinoma Cell ◽  
Carcinoma Cell Line ◽  
Antiproliferative Effect ◽  
Prostatic Cell

scholarly journals Does Bromelain-Cisplatin Combination Afford In-Vitro Synergistic Anticancer Effects on Human Prostatic Carcinoma Cell Line, PC3?

2020 ◽  
Vol 9 ◽  
pp. 1749
Author(s):  
Fatemeh Amini Chermahini ◽  
Elham Raeisi ◽  
Mathias Hossain Aazami ◽  
Abbas Mirzaei ◽  
Esfandiar Heidarian ◽  
...  
Keyword(s):  
Gene Expression ◽  
Cell Viability ◽  
Cell Line ◽  
Colony Formation ◽  
Prostatic Carcinoma ◽  
Carcinoma Cell ◽  
Quantitative Polymerase Chain Reaction ◽  
Chemotherapeutic Agents ◽  
Carcinoma Cell Line

Background: Bromelain enhances anticancer impacts to chemotherapeutic agents. The question as to whether bromelain does promote in-vitro cytotoxic and proapoptotic effects of cisplatin on human prostatic carcinoma PC3 cell line was investigated. Materials and Methods: PC3 (human prostatic carcinoma) cells were treated either single or in combination with bromelain and/or cisplatin. MTT, clonogenic assay, flow cytometry and real-time quantitative polymerase chain reaction were used to investigate cell viability, colony formation, proapoptotic potential and p53 gene expression, respectively. Results: Cisplatin (IC10) combined with bromelain (IC40) significantly affected PC3 cell viability, inhibited colony formation, as well increased p53 proapoptotic gene expression compared to cisplatin single treatment. Nevertheless, bromelain-cisplatin chemoherbal combination did not display any additive proapoptotic effect compared to single treatments. Conclusion: Bromelain-cisplatin chemoherbal combination demonstrated synergistic in-vitro anticancer effect on human prostatic carcinoma cell line, PC3, that drastically reduced required cisplatin dose. [GMJ.2020;9:e1749]

Effects of Hormones on Growth and ATP Content of a Human Prostatic Carcinoma Cell Line, LNCaP-r

1986 ◽  
Vol 135 (4) ◽  
pp. 882-883
Author(s):  
M. Hasenson ◽  
B. Hartley-Asp ◽  
C. Kihlfors ◽  
A. Lundin ◽  
J.-Å. Gustafsson ◽  
...  
Keyword(s):  
Cell Line ◽  
Prostatic Carcinoma ◽  
Carcinoma Cell ◽  
Carcinoma Cell Line ◽  
Atp Content

Inhibitory effects of vincristine, ifosfamide and peplomycin on hormone-independent human prostatic carcinoma cell line

1988 ◽  
Vol 35 (3) ◽  
pp. 141-148
Author(s):  
N. Moriyama-gonda ◽  
M. Mizutani ◽  
S. Ehara ◽  
T. Usui ◽  
T. Ishibe
Keyword(s):  
Cell Line ◽  
Prostatic Carcinoma ◽  
Carcinoma Cell ◽  
Carcinoma Cell Line ◽  
Inhibitory Effects

Establishment and Characterization of a New Human Prostatic Carcinoma Cell Line (DuPro-1)

1991 ◽  
Vol 146 (3) ◽  
pp. 915-919 ◽  
Author(s):  
Jeffrey R. Gingrich ◽  
J. Allan Tucker ◽  
Philip J. Walther ◽  
John W. Day ◽  
Susan H.M. Poulton ◽  
...  
Keyword(s):  
Cell Line ◽  
Prostatic Carcinoma ◽  
Carcinoma Cell ◽  
Carcinoma Cell Line
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