Laparotomic Versus Laparoscopic Duhamel Pull-Through for Hirschsprung Disease in Infants And Children

2007 ◽  
Vol 17 (1) ◽  
pp. 119-123 ◽  
Author(s):  
Vittorina Ghirardo ◽  
Pietro Betalli ◽  
Guendalina Mognato ◽  
Piergiorgio Gamba
Keyword(s):  
Hirschsprung Disease ◽  
Infants And Children ◽  
Pull Through ◽  
In Infants And Children

Histochemical Diagnosis of Hirschsprung Disease

PEDIATRICS ◽  
1982 ◽  
Vol 69 (6) ◽  
pp. 755-761
Author(s):  
Carolyn Coker Huntley ◽  
Louis deS. Shaffner ◽  
Venkata R. Challa ◽  
Anne D. Lyerly
Keyword(s):  
Lamina Propria ◽  
False Positive ◽  
Ganglion Cells ◽  
False Negative ◽  
Hirschsprung Disease ◽  
Nerve Fibers ◽  
Infants And Children ◽  
Muscularis Mucosa ◽  
False Positive Reactions ◽  
In Infants And Children

A histochemical staining technique for detection of acetylcholinesterase (AChE) in rectal suction biopsies was compared with the presence or absence of ganglion cells in full-thickness or suction biopsies for the diagnosis of Hirschsprung disease (HD) in infants and children. Biopsies from 55 of 58 children were adequate for both the AChE assay and routine pathologic examination for ganglion cells. Two patterns of AChE staining were noted. With pattern A, prominent nerve fibers staining for AChE were seen throughout the muscularis mucosa and the lamina propria. With pattern B, similar fibers were seen only in the muscularis mucosa and the areas of lamina propria that were immediately adjacent. No "false-negative" AChE staining reactions were found in patients with HD. No "false-positive" reactions showing pattern A were found. This pattern was diagnostic for HD. Three false-positive reactions were found showing pattern B in patients with conditions other than HD. Among 22 patients with HD, 19 were males and three were females. Pattern A occurred in all age groups and in both sexes. Pattern B in patients with HD was seen exclusively in male infants 1 month of age or less. Experience suggests that the AChE staining of rectal suction biopsies is an excellent screening test for HD in infants and children. If pattern B is encountered, however, the specimen should be examined by routine pathologic techniques for the presence of submucosal ganglion cells.

Understanding Limited Use of Amplification in Infants and Children Who Are Hard of Hearing

2015 ◽  
Vol 25 (1) ◽  
pp. 15-23 ◽  
Author(s):  
Ryan W. McCreery ◽  
Elizabeth A. Walker ◽  
Meredith Spratford
Keyword(s):  
Hard Of Hearing ◽  
Hearing Aid ◽  
Management Strategies ◽  
Infants And Children ◽  
Future Research ◽  
Research Needs ◽  
Case Examples ◽  
Hearing Aid Use ◽  
Wide Range ◽  
In Infants And Children

The effectiveness of amplification for infants and children can be mediated by how much the child uses the device. Existing research suggests that establishing hearing aid use can be challenging. A wide range of factors can influence hearing aid use in children, including the child's age, degree of hearing loss, and socioeconomic status. Audiological interventions, including using validated prescriptive approaches and verification, performing on-going training and orientation, and communicating with caregivers about hearing aid use can also increase hearing aid use by infants and children. Case examples are used to highlight the factors that influence hearing aid use. Potential management strategies and future research needs are also discussed.

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