Neural Correlates of Response Inhibition and Error Processing in Individuals with Mild Traumatic Brain Injury: An Event-Related Potential Study

2020 ◽  
Vol 37 (1) ◽  
pp. 115-124 ◽  
Author(s):  
I-Hsuan Shen ◽  
Ying-Ju Lin ◽  
Chia-Ling Chen ◽  
Cheng-Chih Liao
2018 ◽  
Vol 61 (1) ◽  
pp. 18-26 ◽  
Author(s):  
Gian Candrian ◽  
Andreas Müller ◽  
Patrizia Dall’Acqua ◽  
Kyveli Kompatsiari ◽  
Gian-Marco Baschera ◽  
...  

NeuroImage ◽  
2009 ◽  
Vol 47 ◽  
pp. S178
Author(s):  
M. Mannell ◽  
J. Ling ◽  
C. Gasparovic ◽  
R. Yeo ◽  
R. Elgie ◽  
...  

Brain Injury ◽  
2020 ◽  
Vol 34 (7) ◽  
pp. 871-880
Author(s):  
Offir Laufer ◽  
Amir Geva ◽  
Jonathan D. Ellis ◽  
Kim Barber Foss ◽  
Maayan Ettinger ◽  
...  

2019 ◽  
Vol 9 (6) ◽  
pp. 142 ◽  
Author(s):  
Joanie Drapeau ◽  
Nathalie Gosselin ◽  
Isabelle Peretz ◽  
Michelle McKerral

The present study aimed to measure neural information processing underlying emotional recognition from facial expressions in adults having sustained a mild traumatic brain injury (mTBI) as compared to healthy individuals. We thus measured early (N1, N170) and later (N2) event-related potential (ERP) components during presentation of fearful, neutral, and happy facial expressions in 10 adults with mTBI and 11 control participants. Findings indicated significant differences between groups, irrespective of emotional expression, in the early attentional stage (N1), which was altered in mTBI. The two groups showed similar perceptual integration of facial features (N170), with greater amplitude for fearful facial expressions in the right hemisphere. At a higher-level emotional discrimination stage (N2), both groups demonstrated preferential processing for fear as compared to happiness and neutrality. These findings suggest a reduced early selective attentional processing following mTBI, but no impact on the perceptual and higher-level cognitive processes stages. This study contributes to further improving our comprehension of attentional versus emotional recognition following a mild TBI.


2019 ◽  
Vol 184 (11-12) ◽  
pp. 723-730
Author(s):  
Jill R Settle ◽  
Deborah M Clawson ◽  
Marc M Sebrechts ◽  
Louis M French ◽  
Adreanna T Massey Watts ◽  
...  

Abstract Introduction Prospective memory (PM) is the ability to remember the intention to perform an action in the future. Following mild traumatic brain injury (mTBI), the brain structures supporting such PM may be compromised. PM is essential for remembering activities specific to TBI survivors that promote recovery, such as following doctors’ orders, taking necessary medications, completing physical rehabilitation exercises, and maintaining supportive social relationships. Since the year 2000, more than 315,897 US Service Members are reported to have sustained an mTBI1, yet little has been done to address possible PM concerns. Therefore, identifying impaired PM and interventions that may ameliorate such deficits is important. The primary aim of this study was to determine whether task encoding using implementation intentions leads to better PM performance than encoding using rote rehearsal in Service Members with mTBI (n = 35) or with bodily injuries but no TBI (n = 8) at baseline and 6 months later. Materials and Method Participants were randomized to one of the two encoding conditions. They were asked to remember to complete a series of four tasks over the course of a 2-hour event-related potential session and to contact a staff member during a specified 2-hour window later that day. PM performance was assessed based on completion of each task at the appropriate time. IRB approval was obtained from The Catholic University of America, Walter Reed National Military Medical Center, and Ft. Belvoir Community Hospital. Results Service Members with mTBI using implementation intentions outperformed those using rote rehearsal. The effect of injury type and the interaction between encoding condition and injury type did not yield differences that were statistically significant. Conclusions The results suggest that implementation intentions may be a useful PM remediation strategy for those who have sustained mTBI. Future research should validate these findings in a larger sample


2019 ◽  
Vol 34 (6) ◽  
pp. 1021-1021
Author(s):  
K Holiday ◽  
A Clark ◽  
S Sorg ◽  
V Merritt ◽  
M Nakhla ◽  
...  

Abstract Objective Veterans with mild traumatic brain injury (mTBI) frequently report cognitive difficulties, though these are not always supported by objective neuropsychological testing. The current study compared mTBI Veterans with subjective disinhibition to Veteran Controls (VC) on an objective response inhibition task while controlling for depression. Methods 53 mTBI Veterans and 31 VC with optimal effort completed a go/no-go response inhibition (RI) task and measures of subjective disinhibition (Frontal Systems Executive Behavior scale) and depression (Beck Depression Inventory-II). ANCOVAs compared RI performances of VC without cognitive complaints to (1) the total sample of mTBI Veterans and (2) to mTBI Veterans with (t-score>60; mTBI+disinhibition; n = 23) and without (t-score < 60; mTBI-disinhibition; n = 30) subjective complaints of disinhibition. Results Relative to the VC group, the mTBI Veterans endorsed significantly greater depressive symptoms (p < .001). No significant differences in RI performance were observed when the total mTBI sample was compared to VC. However, in the three group analysis, there was a significant effect of group (p = .002) controlling for depression (p = .396). Post-hoc analyses revealed the mTBI+disinhibition group performed significantly worse than the mTBI-disinhibition (p < .001) and VC (p < .001) groups; no significance differences in RI performance were observed between the mTBI-disinhibition and VC groups (p = .914). Conclusions While the larger mTBI group did not differ from VC on RI performance, mTBI Veterans with subjective disinhibition complaints evidenced poorer objective RI. Findings therefore suggest that Veterans with elevated subjective complaints may be at risk for experiencing objective cognitive difficulties. Future research is needed to elucidate the neural underpinnings of these group differences as well as clinical outcomes.


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