scholarly journals Evaluation of Angiogenesis of Bioactive Glass in the Arteriovenous Loop Model

2013 ◽  
Vol 19 (6) ◽  
pp. 479-486 ◽  
Author(s):  
Andreas Arkudas ◽  
Amelie Balzer ◽  
Gregor Buehrer ◽  
Isabel Arnold ◽  
Alexander Hoppe ◽  
...  
2016 ◽  
Vol 2 (1) ◽  
Author(s):  
Gregor Bührer ◽  
Ulrike Rottensteiner ◽  
Alexander Hoppe ◽  
Rainer Detsch ◽  
Diana Dafinova ◽  
...  

Abstracteffects of 3D scaffolds made from 45S5 bioactive glass (BG) doped with 1 wt. % copper ions in the arteriovenous loop model of the rat.Materials and Methods: An arteriovenous loop was built in the groin of 10 rats and inserted in 1% copper doped 45S5 BG scaffolds and fibrin. The scaffold and the AV loop were inserted in Teflon isolation chambers and explanted 3 weeks after implantation. Afterwards the scaffolds were analyzed by Micro-CT and histology regarding vascularization. Results were compared to plain 45S5 BG-based scaffolds from a previous study.Results: Micro-CT and histological evaluation showed consistent vascularization of the constructs. A tendency towards an increased vascularization in the copper doped BG group compared to plain BG constructs could be observed. However, therewas no significant difference in statistical analysis between both groups.Conclusions: This study shows results that support an increased angiogenetic effect of 1% copper doped 45S5 BG compared to regular 45S5 BG scaffolds in the rat arteriovenous loop model although these tendencies are not backed by statistical evidence. Maybe higher copper doses could lead to a statistically significant angiogenetic effect.


Author(s):  
Jan W. Robering ◽  
Majida Al-Abboodi ◽  
Adriana Titzmann ◽  
Inge Horn ◽  
Justus P. Beier ◽  
...  

2011 ◽  
Vol 46 (3) ◽  
pp. 148-155 ◽  
Author(s):  
J.P. Beier ◽  
A. Hess ◽  
J. Loew ◽  
J. Heinrich ◽  
A.M. Boos ◽  
...  

2012 ◽  
Vol 7 (8) ◽  
pp. 654-664 ◽  
Author(s):  
Anja M. Boos ◽  
Johanna S. Loew ◽  
Annika Weigand ◽  
Gloria Deschler ◽  
Dorothee Klumpp ◽  
...  

2010 ◽  
Vol 27 (01) ◽  
pp. 011-018 ◽  
Author(s):  
Elias Polykandriotis ◽  
Dimitris Drakotos ◽  
Andreas Arkudas ◽  
Galyna Pryymachuk ◽  
Subha Rath ◽  
...  

2019 ◽  
Vol 25 (21-22) ◽  
pp. 1504-1513 ◽  
Author(s):  
Dominik Steiner ◽  
Gregor Lang ◽  
Laura Fischer ◽  
Sophie Winkler ◽  
Tobias Fey ◽  
...  

2016 ◽  
Vol 79 (10) ◽  
pp. 899-907 ◽  
Author(s):  
Hannes Seuss ◽  
Andreas Arkudas ◽  
Matthias Hammon ◽  
Oliver Bleiziffer ◽  
Michael Uder ◽  
...  

2021 ◽  
Author(s):  
Dominik Steiner ◽  
Sophie Winkler ◽  
Stefanie Heltmann-Meyer ◽  
Vanessa Trossmann ◽  
Tobias Fey ◽  
...  

Planta Medica ◽  
2009 ◽  
Vol 75 (09) ◽  
Author(s):  
RFA Bonfim ◽  
VR Chitarra ◽  
RT Gomes ◽  
RD Zacarias ◽  
VR Santos ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document