Suppressor T Lymphocyte Dysfunction Is Important in the Pathogenesis of Autoimmune Thyroid Disease: A Perspective

Thyroid ◽  
1993 ◽  
Vol 3 (4) ◽  
pp. 345-352 ◽  
Author(s):  
ROBERT VOLPÉ
Keyword(s):  
T Lymphocyte ◽  
Thyroid Disease ◽  
Autoimmune Thyroid Disease ◽  
Autoimmune Thyroid ◽  
Suppressor T Lymphocyte

Infiltrating T-lymphocyte Receptor Vβ Gene Family Utilization in Autoimmune Thyroid Disease

2006 ◽  
Vol 34 (6) ◽  
pp. 585-595 ◽  
Author(s):  
J Zhang ◽  
M Zhang ◽  
Y Wang ◽  
B Shi ◽  
B Zhu ◽  
...  
Keyword(s):  
Gene Family ◽  
T Lymphocyte ◽  
Thyroid Disease ◽  
Autoimmune Thyroid Disease ◽  
Autoimmune Thyroid

49A/G and CT60 polymorphisms of the cytotoxic T-lymphocyte-associated antigen 4 gene associated with autoimmune thyroid disease

2009 ◽  
Vol 70 (10) ◽  
pp. 820-824 ◽  
Author(s):  
Ajda Bicek ◽  
Katja Zaletel ◽  
Simona Gaberscek ◽  
Edvard Pirnat ◽  
Blaz Krhin ◽  
...  
Keyword(s):  
T Lymphocyte ◽  
Thyroid Disease ◽  
Autoimmune Thyroid Disease ◽  
Cytotoxic T Lymphocyte ◽  
Autoimmune Thyroid

scholarly journals CTLA-4 and its role in autoimmune thyroid disease

2003 ◽  
Vol 31 (1) ◽  
pp. 21-36 ◽  
Author(s):  
DA Chistiakov ◽  
RI Turakulov
Keyword(s):  
T Lymphocyte ◽  
Thyroid Disease ◽  
Autoimmune Thyroid Disease ◽  
Cytotoxic T Lymphocyte ◽  
Thyroid Autoimmunity ◽  
Hashimoto Thyroiditis ◽  
Gene Encoding ◽  
Autoimmune Thyroid ◽  
Functional Studies

Autoimmune thyroid disease (AITD) occurs in two common forms: Graves' disease and Hashimoto thyroiditis. On the basis of functional and experimental data, it has been suggested that the gene encoding cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) is a candidate gene for conferring susceptibility to thyroid autoimmunity. In this review, we critically evaluate the evidence for pathogenetic involvement of CTLA-4 in the various forms of AITD and focus on the possible role of genetic variation of the CTLA4 locus. Population genetics data strongly suggest a role for the CTLA4 region in susceptibility to AITD. However, further functional studies are required to understand the significance of CTLA4 polymorphisms in the pathogenic mechanism of AITD.

scholarly journals The role of T-lymphocyte subsets and interleukin-5 blood levels among Indian subjects with autoimmune thyroid disease

HORMONES ◽  
2010 ◽  
Vol 9 (1) ◽  
pp. 76-81 ◽  
Author(s):  
Sripathy Gopalakrishnan ◽  
Sourav Sen ◽  
Jawahar Singh Adhikari ◽  
Pradeep Kumar Chugh ◽  
Tarun Sekhri ◽  
...  
Keyword(s):  
T Lymphocyte ◽  
Thyroid Disease ◽  
Autoimmune Thyroid Disease ◽  
Lymphocyte Subsets ◽  
Blood Levels ◽  
T Lymphocyte Subsets ◽  
Autoimmune Thyroid ◽  
Interleukin 5

Polymorphism in the Promoter and Exon 1 of the Cytotoxic T Lymphocyte Antigen-4 Gene Associated with Autoimmune Thyroid Disease in Koreans

Thyroid ◽  
2000 ◽  
Vol 10 (6) ◽  
pp. 453-459 ◽  
Author(s):  
Young Joo Park ◽  
Hyun Kyung Chung ◽  
Do Joon Park ◽  
Won Bae Kim ◽  
Sun Wook Kim ◽  
...  
Keyword(s):  
T Lymphocyte ◽  
Thyroid Disease ◽  
Autoimmune Thyroid Disease ◽  
Cytotoxic T Lymphocyte ◽  
Lymphocyte Antigen ◽  
Autoimmune Thyroid ◽  
Exon 1

scholarly journals Cytotoxic T-Lymphocyte Associated Antigen 4 Gene Polymorphisms and Autoimmune Thyroid Disease: A Meta-Analysis

2007 ◽  
Vol 92 (8) ◽  
pp. 3162-3170 ◽  
Author(s):  
Fotini K. Kavvoura ◽  
Takashi Akamizu ◽  
Takuya Awata ◽  
Yoshiyuki Ban ◽  
Dimitry A. Chistiakov ◽  
...  
Keyword(s):  
T Lymphocyte ◽  
Thyroid Disease ◽  
Gene Polymorphisms ◽  
Autoimmune Thyroid Disease ◽  
Cytotoxic T Lymphocyte ◽  
Meta Analysis ◽  
Autoimmune Thyroid

The role of T-lymphocyte subsets and interleukin-5 blood levels among Indian subjects with autoimmune thyroid disease

HORMONES ◽  
2010 ◽  
Vol 9 (1) ◽  
pp. 76-81
Author(s):  
Sripathy Gopalakrishnan ◽  
Sourav Sen ◽  
Jawahar Singh Adhikari ◽  
Pradeep Kumar Chugh ◽  
Tarun Sekhri ◽  
...  
Keyword(s):  
T Lymphocyte ◽  
Thyroid Disease ◽  
Autoimmune Thyroid Disease ◽  
Lymphocyte Subsets ◽  
Blood Levels ◽  
T Lymphocyte Subsets ◽  
Autoimmune Thyroid ◽  
Interleukin 5
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