Ultrasound-Guided Radiofrequency Ablation Versus Thyroid Lobectomy for Low-Risk Papillary Thyroid Microcarcinoma: A Propensity-matched Cohort Study of 884 Patients

Thyroid ◽  
2021 ◽  
Author(s):  
Lin Yan ◽  
Mingbo Zhang ◽  
Qing Song ◽  
Yukun Luo
Keyword(s):  
Cohort Study ◽  
Radiofrequency Ablation ◽  
Low Risk ◽  
Papillary Thyroid Microcarcinoma ◽  
Matched Cohort ◽  
Papillary Thyroid ◽  
Ultrasound Guided ◽  
Matched Cohort Study ◽  
Thyroid Microcarcinoma ◽  
Thyroid Lobectomy

scholarly journals Long-Term Follow-Up Results of Ultrasound-Guided Radiofrequency Ablation for Low-Risk Papillary Thyroid Microcarcinoma: More Than 5-Year Follow-Up for 84 Tumors

Thyroid ◽  
2020 ◽  
Vol 30 (12) ◽  
pp. 1745-1751 ◽  
Author(s):  
Se Jin Cho ◽  
Sun Mi Baek ◽  
Hyun Kyung Lim ◽  
Kang Dae Lee ◽  
Jung Min Son ◽  
...  
Keyword(s):  
Radiofrequency Ablation ◽  
Low Risk ◽  
Papillary Thyroid Microcarcinoma ◽  
Papillary Thyroid ◽  
Ultrasound Guided ◽  
Thyroid Microcarcinoma ◽  
Long Term Follow Up

scholarly journals A comparison of lobectomy and total thyroidectomy in patients with papillary thyroid microcarcinoma: a retrospective individual risk factor-matched cohort study

2017 ◽  
Vol 176 (4) ◽  
pp. 371-378 ◽  
Author(s):  
Hyemi Kwon ◽  
Min Ji Jeon ◽  
Won Gu Kim ◽  
Suyeon Park ◽  
Mijin Kim ◽  
...  
Keyword(s):  
Risk Factor ◽  
Cohort Study ◽  
Total Thyroidectomy ◽  
Papillary Thyroid Microcarcinoma ◽  
Individual Risk ◽  
Matched Cohort ◽  
Papillary Thyroid ◽  
Individual Risk Factor ◽  
Matched Cohort Study ◽  
Thyroid Microcarcinoma

Objective Papillary thyroid microcarcinoma (PTMC) accounts for most of the increase in thyroid cancer in recent decades. We compared clinical outcomes and surgical complications of lobectomy and total thyroidectomy (TT) in PTMC patients. Design and methods In this retrospective individual risk factor-matched cohort study, 2031 patients with PTMC were initially included. Patients who underwent lobectomy or TT were one-to-one matched according to individual risk factors, including age, sex, primary tumor size, extrathyroidal extension, multifocality and cervical lymph node (LN) metastasis. Results In total, 688 patients were assigned to each group. During the median 8.5 years of follow-up, 26 patients (3.8%) in the lobectomy group and 11 patients (1.6%) in the TT group had recurrences. The relative risk of recurrence was significantly less in the TT than that in the lobectomy group (hazard ratio (HR) 0.41; 95% confidence interval (CI) 0.21–0.81; P = 0.01). Most recurrences (84.6%) in the lobectomy group occurred in the contralateral lobe, and all patients were disease-free after completion of thyroidectomy. There were no significant differences in recurrence-free survival between the two groups after exclusion of contralateral lobe recurrences (HR, 2.75; 95% CI, 0.08–8.79; P = 0.08). There were significantly more patients with transient and permanent hypoparathyroidism in the TT than that in the lobectomy group (P < 0.001). Conclusions Lobectomy could be appropriate for most patients with PTMC when there is no evidence of extrathyroidal disease in the preoperative work-up. Preoperative and postoperative imaging studies are important for patients who undergo lobectomy for PTMC, because most recurrences are in the contralateral lobe.

Ultrasound-Guided Radiofrequency Ablation Versus Surgery for Low-Risk Papillary Thyroid Microcarcinoma: Results of Over 5 Years' Follow-Up

Thyroid ◽  
2020 ◽  
Vol 30 (3) ◽  
pp. 408-417 ◽  
Author(s):  
Mingbo Zhang ◽  
Ralph P. Tufano ◽  
Jonathon O. Russell ◽  
Ying Zhang ◽  
Yan Zhang ◽  
...  
Keyword(s):  
Radiofrequency Ablation ◽  
Low Risk ◽  
Papillary Thyroid Microcarcinoma ◽  
Papillary Thyroid ◽  
Ultrasound Guided ◽  
Thyroid Microcarcinoma

scholarly journals A cohort study of microwave ablation and surgery for low-risk papillary thyroid microcarcinoma

2021 ◽  
Vol 38 (1) ◽  
pp. 1548-1557
Author(s):  
Yuan Zu ◽  
Yujiang Liu ◽  
Junfeng Zhao ◽  
Peipei Yang ◽  
Jianming Li ◽  
...  
Keyword(s):  
Cohort Study ◽  
Microwave Ablation ◽  
Low Risk ◽  
Papillary Thyroid Microcarcinoma ◽  
Papillary Thyroid ◽  
Thyroid Microcarcinoma
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