scholarly journals Using Zebrafish to Implement a Course-Based Undergraduate Research Experience to Study Teratogenesis in Two Biology Laboratory Courses

Zebrafish ◽  
2016 ◽  
Vol 13 (4) ◽  
pp. 293-304 ◽  
Author(s):  
Swapnalee Sarmah ◽  
Grady W. Chism ◽  
Martin A. Vaughan ◽  
Pooja Muralidharan ◽  
Jim A. Marrs ◽  
...  
Author(s):  
Jeffrey Kovac

Just as in chemistry, the best way to learn ethical problem solving is to confront context-rich, real-life problems (Jonsen and Toulmin 1988; Davis 1999, 143–175). The broad variety of ethical problems, or cases, presented here are hypothetical situations, but represent the kinds of problems working chemists and students face. Cases raising similar ethical questions are grouped together. To reach a diverse audience, I sometimes write several variations of the same situation. For example, a question might be posed from the perspective of the graduate student in one version and from the perspective of the research di­rector in another. For important issues I provide cases that are accessible to undergraduates who have very little research experience, usually in the context of laboratory courses. For advanced undergraduates, some cases involve undergraduate research projects. Most of the cases involve situations encountered in graduate research in universities, but some also concern industrial chemistry. Finally, a few cases present ethical problems that arise in cooperative learning, a pedagogical technique that is becoming increasingly important in undergraduate education. Each case, or related set of cases, is followed by a commentary that outlines the important issues and discusses possible solutions. Some of the commentaries are quite extensive and actually present and defend my preferred course of action; others are brief and merely raise questions that should be considered in designing a solution. The commentaries model the ethical problem-solving method presented in Chapter 6. As I have emphasized repeatedly, most ethical problems do not have clean solutions. While some courses of action are clearly wrong, there may be several morally acceptable and defensible ways to proceed. Consequently, readers might disagree with my proposed solutions for good reasons. For example, if I use a consequentialist approach, my assessment of the relative positive and negative weights of the consequences might be challenged, or I simply might have forgotten to consider some factor. Where I have made a definite recommendation, I give the reasons for my choice and contrast it with other alternatives.


2014 ◽  
Vol 13 (4) ◽  
pp. 711-723 ◽  
Author(s):  
David Lopatto ◽  
Charles Hauser ◽  
Christopher J. Jones ◽  
Don Paetkau ◽  
Vidya Chandrasekaran ◽  
...  

In their 2012 report, the President's Council of Advisors on Science and Technology advocated “replacing standard science laboratory courses with discovery-based research courses”—a challenging proposition that presents practical and pedagogical difficulties. In this paper, we describe our collective experiences working with the Genomics Education Partnership, a nationwide faculty consortium that aims to provide undergraduates with a research experience in genomics through a scheduled course (a classroom-based undergraduate research experience, or CURE). We examine the common barriers encountered in implementing a CURE, program elements of most value to faculty, ways in which a shared core support system can help, and the incentives for and rewards of establishing a CURE on our diverse campuses. While some of the barriers and rewards are specific to a research project utilizing a genomics approach, other lessons learned should be broadly applicable. We find that a central system that supports a shared investigation can mitigate some shortfalls in campus infrastructure (such as time for new curriculum development, availability of IT services) and provides collegial support for change. Our findings should be useful for designing similar supportive programs to facilitate change in the way we teach science for undergraduates.


2019 ◽  
Author(s):  
Christina E. D’Arcy ◽  
Anais Martinez ◽  
Arshad M. Khan ◽  
Jeffrey T. Olimpo

AbstractCourse-based undergraduate research experiences (CUREs) engage emerging scholars in the authentic process of scientific discovery, and foster their development of content knowledge, motivation, and persistence in the science, technology, engineering, and mathematics (STEM) disciplines. Importantly, authentic research courses simultaneously offer investigators unique access to an extended population of students who receive education and mentoring in conducting scientifically relevant investigations and who are thus able to contribute effort toward big-data projects. While this paradigm benefits fields in neuroscience, such as atlas-based brain mapping of nerve cells at the tissue level, there are few documented cases of such laboratory courses offered in the domain.Here, we describe a curriculum designed to address this deficit, evaluate the scientific merit of novel student-produced brainatlasmapsofimmunohistochemically-identifiednervecellpopulations for the rat brain, and assess shifts in science identity, attitudes, and science communication skills of students engaged in the introductory-level Brain Mapping and Connectomics (BM&C) CURE. BM&C students reported gains in research and science process skills following participation in the course. Furthermore, BM&C students experienced a greater sense of science identity, including a greater likelihood to discuss course activities with non-class members compared to their non-CURE counterparts. Importantly, evaluation of student-generated brain atlas maps indicated that the course enabled students to produce scientifically valid products and make new discoveries to advance the field of neuroanatomy. Together, these findings support the efficacy of the BM&C course in addressing the relatively esoteric demands of chemoarchitectural brain mapping.


2021 ◽  
Vol 83 (1) ◽  
pp. 48-54
Author(s):  
Erika C. Martin

This project involves students in a course-based undergraduate research experience (CURE) as part of the traditional introductory biology laboratory course. Recently, research has shown that student engagement in authentic research has significant positive impacts on students, such as development of science literacy and reasoning skills. Being recently featured in the news, microplastics are a timely, interesting, and relevant topic for students. The authentic research conducted by students was the first attempt at quantification of microplastics in the Great Plains, which garnered further student excitement and engagement. Surface water and substrate samples were collected at 23 locations from small streams, rivers, ponds, and reservoirs in fall 2018. Authentic research, as broadly defined in the pedagogical context, is research conducted primarily by students. In the context of this project, authentic research is specifically defined as research done primarily by students in which the students are asking questions, designing experiments, collecting and analyzing data, and writing a final manuscript that was submitted, and accepted, as a peer-reviewed publication. This project could be incorporated at the high school or university level, for biology major or nonmajor courses. The purpose of this paper is to serve as a how-to, sharing the lesson design with specific detail on student responsibilities.


2018 ◽  
Author(s):  
Lydia K. Fox ◽  
◽  
Sarah K. Fortner ◽  
Erin Kraal ◽  
Carolyn Wilson

2020 ◽  
Vol 367 (21) ◽  
Author(s):  
Jennifer K Lyles ◽  
Monika Oli

ABSTRACT A course-based undergraduate research experience (CURE) was designed to integrate key microbiological principles and techniques into an authentic research experience in a classroom setting and was implemented in an undergraduate microbiology laboratory course. Students conducted a 6-week study in order to determine the identity and quantity of unique probiotic species from various types of kefir. This course module followed an inquiry-based pedagogical approach in which students use the scientific process to investigate an unknown question with no predetermined outcome. During each lab, relevant microbiological topics and laboratory concepts were presented. Students then performed various laboratory techniques, reinforcing the lecture material with hands-on experience. In addition, students participated in reflection through group presentation of their results, bioinformatic analysis and literature review. Based on data collected from pre- and post-study survey responses, both student knowledge and attitudes towards the topics covered improved due to participation in this CURE. Importantly, this CURE can be implemented at many levels of education, requiring only minimal resources and common laboratory equipment.


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