scholarly journals Amniotic fluid-derived stem cells mixed with platelet rich plasma for restoration of rat alveolar bone defect

Author(s):  
Minjiao Wang ◽  
Hongliang Li ◽  
Jiawen Si ◽  
Jiewen Dai ◽  
Jun Shi ◽  
...  
2015 ◽  
Vol 61 (11/2015) ◽  
Author(s):  
Muhetaer Huojia ◽  
Wu Zhongming ◽  
Zhang Xiaoli ◽  
Maibubaimu Maimaitiyiming ◽  
Ma Rong

Medicina ◽  
2021 ◽  
Vol 57 (2) ◽  
pp. 180 ◽  
Author(s):  
Rodolfo Mauceri ◽  
Denise Murgia ◽  
Orazio Cicero ◽  
Luigi Paternò ◽  
Luca Fiorillo ◽  
...  

The management of critical-size bone defects is still demanding. Recently, autologous platelet concentrates in combination with bone substitute have been applied and reported in a few studies. Our aim is to report the healing of a critical-size alveolar bone defect treated with a new bone regeneration technique by means of L-PRF and L-PRF blocks. A 45-year-old woman presented a large cystic lesion; the extraction of three teeth, a cyst removal procedure, and bone regeneration procedures with L-PRF and L-PRF blocks were planned. The L-PRF block was prepared by mixing a bone substitute with a piece of L-PRF membrane and liquid fibrinogen. Additionally, after bone healing an implant-based rehabilitation was optimally performed. On the basis of the positive results, in terms of bone healing and tissue regeneration in a large bone defect, the application of L-PRF and L-PRF blocks, in agreement with the scarce literature, is suggested as a feasible procedure in selected cases.


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