Dependence of the effects of dietary cholesterol and experimental conditions on serum lipids in man III. The effect on serum cholesterol of removal of eggs from the diet of free-living habitually egg-eating people

1979 ◽  
Vol 32 (11) ◽  
pp. 2193-2197 ◽  
Author(s):  
D C Bronsgeest-Schoute ◽  
R J J Hermus ◽  
G M Dallinga-Thie ◽  
J G A J Hautvast
Keyword(s):  
Serum Cholesterol ◽  
Serum Lipids ◽  
Dietary Cholesterol ◽  
Free Living ◽  
Experimental Conditions

scholarly journals Apolipoprotein A4-1/2 polymorphism and response of serum lipids to dietary cholesterol in humans

2000 ◽  
Vol 41 (10) ◽  
pp. 1623-1628
Author(s):  
Rianne M. Weggemans ◽  
Peter L. Zock ◽  
Saskia Meyboom ◽  
Harald Funke ◽  
Martijn B. Katan
Keyword(s):  
Serum Lipids ◽  
Dietary Cholesterol

Dietary Cholesterol-Induced Down-Regulation of Intestinal 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Activity Is Diminished in Rabbits with Hyperresponse of Serum Cholesterol to Dietary Cholesterol

1993 ◽  
Vol 123 (4) ◽  
pp. 695-703 ◽  
Author(s):  
Gert W. Meijer ◽  
Martin J. Smit ◽  
Johan G. P. van der Palen ◽  
Folkert Kuipers ◽  
Roel J. Vonk ◽  
...  
Keyword(s):  
Serum Cholesterol ◽  
Coenzyme A ◽  
Reductase Activity ◽  
Dietary Cholesterol ◽  
Down Regulation ◽  
Coenzyme A Reductase

scholarly journals 0127 Relationship Between Sleep Metrics with Free-Living Glucose Concentrations and Glycemic Variability in Non-Diabetic Adults

SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A50-A50
Author(s):  
J R Sparks ◽  
E E Kishman ◽  
X Wang
Keyword(s):  
South Carolina ◽  
Glucose Metabolism ◽  
Sleep Onset ◽  
Glycemic Variability ◽  
Sleep Efficiency ◽  
Sleep Diary ◽  
Poor Sleep ◽  
Free Living ◽  
Experimental Conditions ◽  
Time In Bed

Abstract Introduction Insufficient sleep and poor sleep quality have been associated with impaired glucose metabolism at fasting and under experimental conditions. Continuous glucose monitoring (CGM) measures glucose concentrations over an extended, free-living period that can be used to assess glycemic health. Relationships between CGM-assessed glucose concentrations and glycemic variability, an emerging glycemic health marker, with sleep metrics have yet to be elucidated. The purpose of this study was to examine the relationships between sleep metrics with glucose concentrations and glycemic variability in non-diabetic adults. Methods Twenty-four non-diabetic adults (age=46.0±5.8 years; BMI=32.2±5.7 kg/m2) completed actigraphy, sleep diary, and CGM over 7 consecutive days. Time-in-bed (TIB), total sleep time (TST), wake duration after sleep onset, and sleep efficiency [(TST÷TIB)×100%] were determined using actigraphy assisted with sleep diary input. Nightly variability of each sleep metric was calculated as standard deviation (SD) across all nights. Glucose concentrations at waking in the morning, and 1, 2, and 3 hours prior to waking, and diurnal, nocturnal, and 24-hour means were determined. Intra-day glycemic variability, including mean amplitude of glycemic excursions and continuous overlapping of net glycemic action of 1, 2, and 4 hours, and inter-day glycemic variability, mean of daily differences, were calculated. Pearson product correlations between sleep metrics with glucose concentrations and glycemic variability were performed. Results Average TIB and TST were 462.6±61.7 minutes and 403.3±59.7 minutes, respectively. TIB negatively correlated with glucose concentrations at 2 and 3 hours prior to waking (r=-0.42, p=0.04 and r=-0.42, p=0.04, respectively). Nightly variability in sleep efficiency positively correlated with waking, and 1, 2, and 3 hours prior to waking glucose concentrations (0.44≤r≤0.48, p≤0.03 for all). No sleep metrics correlated with glycemic variability measures (p≥0.10 for all). Conclusion Findings suggest a longer amount of sleep opportunity and more consistent sleep efficiency relate to better glucose metabolism in non-diabetic adults. Support American Heart Association 14BGIA20380706 and University of South Carolina Support to Promote Advancement of Research and Creativity Grant #11530-17-43917.

A PROPOSED MECHANISM FOR THE EFFECT OF DIFFERENT DIETARY FATS ON SOME ASPECTS OF CHOLESTEROL METABOLISM

1962 ◽  
Vol 40 (1) ◽  
pp. 1091-1100 ◽  
Author(s):  
J. A. Wilkens ◽  
H. de Wit ◽  
B. Bronte-Stewart
Keyword(s):  
Fatty Acids ◽  
Serum Cholesterol ◽  
Cholesterol Metabolism ◽  
Dietary Cholesterol ◽  
Serum Levels ◽  
High Serum ◽  
Dietary Fats ◽  
Cholesterol Concentration ◽  
Serum Cholesterol Concentration ◽  
Endogenous Cholesterol

To explain the effect of dietary cholesterol and different fats on serum cholesterol concentration a hypothesis is proposed according to which the condition for the absorption of dietary cholesterol is its state of solution in dietary or endogenous fats. Dietary fats, free from cholesterol, exert their effect on serum cholesterol concentration by causing reabsorption of biliary or endogenous cholesterol. To test this hypothesis the solubility of cholesterol in a number of natural and modified triglyceride fats at 37 °C was determined and found to correlate with the effects of these fats on the serum cholesterol concentration of rats and man. Relatively high solubilities were associated with high serum levels and vice versa. Artificial modification of both unsaponifiable matter and fatty acids of triglyceride oils was found to alter the solubility of cholesterol in these oils. The solubility concept is discussed as a possible mechanism underlying the effect of different dietary fats on serum cholesterol concentration and other aspects of cholesterol metabolism such as absorption, excretion, and liver synthesis.

Dietary Fiber and Lifestyle Influence Serum Lipids in Free Living Adult Men

2001 ◽  
Vol 20 (6) ◽  
pp. 649-655 ◽  
Author(s):  
Martha N. Ballesteros ◽  
Rosa M. Cabrera ◽  
Maria S. Saucedo ◽  
Gloria M. Yepiz-Plascencia ◽  
M. Isabel Ortega ◽  
...  
Keyword(s):  
Dietary Fiber ◽  
Serum Lipids ◽  
Free Living ◽  
Adult Men ◽  
Living Adult

VARIOUS EFFECTS OF THYROXINE ANALOGUES ON THE HEART AND SERUM CHOLESTEROL IN THE RAT

1960 ◽  
Vol 21 (1) ◽  
pp. 25-32 ◽  
Author(s):  
G. S. BOYD ◽  
M. F. OLIVER
Keyword(s):  
Heart Rate ◽  
Oxygen Consumption ◽  
Serum Cholesterol ◽  
Rate Ratio ◽  
Heart Weight ◽  
Liver Cholesterol ◽  
Response Curves ◽  
Experimental Conditions ◽  
Cholesterol Levels ◽  
Stimulation Of

SUMMARY A series of twelve iodinated thyroxine analogues was studied for thyro-activity in the rat. Each analogue produced antigoitrogenic activity, increased oxygen consumption, heart rate and heart weight, and decreased serum and liver cholesterol levels. A 'serum cholesterol/heart rate ratio' may be computed for these analogues under fixed experimental conditions. While the dose-response curves for different analogues in any of these assays are rarely parallel, it is, nevertheless, clear that under certain experimental conditions some iodothyronines cause a relatively greater depression of cholesterol levels and less stimulation of heart rate than others. Some of the most active in this respect are DT4, DT3, DT2 and T4F.

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