Dependence of the effects of dietary cholesterol and experimental conditions on serum lipids in man I. Effects of dietary cholesterol in a linoleic acid-rich diet

1979 ◽  
Vol 32 (11) ◽  
pp. 2183-2187 ◽  
Author(s):  
D C Bronsgeest-Schoute ◽  
J G A J Hautvast ◽  
R J J Hermus
Keyword(s):  
Linoleic Acid ◽  
Serum Lipids ◽  
Dietary Cholesterol ◽  
Experimental Conditions

scholarly journals Apolipoprotein A4-1/2 polymorphism and response of serum lipids to dietary cholesterol in humans

2000 ◽  
Vol 41 (10) ◽  
pp. 1623-1628
Author(s):  
Rianne M. Weggemans ◽  
Peter L. Zock ◽  
Saskia Meyboom ◽  
Harald Funke ◽  
Martijn B. Katan
Keyword(s):  
Serum Lipids ◽  
Dietary Cholesterol

FATTY ACID COMPOSITION OF SERUM LIPIDS IN HYPER- AND HYPOTHYROIDISM

1972 ◽  
Vol 71 (1) ◽  
pp. 62-72 ◽  
Author(s):  
Knut Kirkeby
Keyword(s):  
Fatty Acids ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Linoleic Acid ◽  
Acid Composition ◽  
Serum Lipids ◽  
Unsaturated Fatty Acids ◽  
Eicosatrienoic Acid ◽  
High Linoleic Acid ◽  
Absolute Concentrations

ABSTRACT The fatty acid composition of cholesterol esters, phospholipids, and triglycerides of the serum has been studied in groups of hyperthyroid and hypothyroid women and also in control material matched for age. In hyperthyroidism, a decrease in the proportions of linoleic acid and an increase in the proportions of some saturated and mono-unsaturated fatty acids were observed. When absolute concentrations were considered, it appeared that the decrease in linoleic acid was almost equivalent to the entire decrease in total fatty acids in the serum of the hyperthyroid patients. In hypothyroidism no changes were noted in the proportions of linoleic, saturated and mono-unsaturated fatty acids, and the absolute concentrations reflected the general increase in serum lipids. It is believed that these findings may be explained by the changes in lipid turnover which are known to occur in disturbances of thyroid function. In hyperthyroidism, they lead to a linoleic acid deficiency, while a sparing effect must be operating in hypothyroidism. The finding of relatively high linoleic acid values combined with hyperlipaemia in hypothyroidism seems to be characteristic of the condition, since other types of hyperlipaemia are almost invariably combined with low percentages of linoleic acid. Results regarding arachidonic and eicosatrienoic acid are consistent with increased synthesis in hyperthyroidism, and decreased synthesis in hypothyroidism.

Effects of trans-10, cis-12 conjugated linoleic acid on body fat and serum lipids in young and adult hamsters

2006 ◽  
Vol 62 (2) ◽  
pp. 81-87 ◽  
Author(s):  
V. Navarro ◽  
J. Miranda ◽  
I. Churruca ◽  
A. Fernández-Quintela ◽  
V. M. Rodríguez ◽  
...  
Keyword(s):  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Body Fat ◽  
Serum Lipids

scholarly journals The Association of Dietary Cholesterol and Fatty Acids with Dyslipidemia in Chinese Metropolitan Men and Women

Nutrients ◽  
2018 ◽  
Vol 10 (8) ◽  
pp. 961 ◽  
Author(s):  
Zhenni Zhu ◽  
Fan Wu ◽  
Ye Lu ◽  
Zhengyuan Wang ◽  
Jiajie Zang ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Serum Lipids ◽  
Partial Correlation ◽  
Dietary Cholesterol ◽  
Correlation Coefficients ◽  
Dietary Fatty Acids ◽  
Laboratory Measurements ◽  
High Tc ◽  
Cholesterol Intake ◽  
High Level

Background: The associations between dietary cholesterol and fatty acids and serum lipids are controversial. This study is to examine the association of dietary cholesterol and fatty acids with serum lipids and dyslipidemia in Chinese metropolitan male and female adults. Methods: 3850 participants in the Shanghai Diet and Health Survey were investigated during the period 2012–2013. Information was obtained on dietary intake, anthropometric and blood laboratory measurements. Dyslipidemia was determined by US National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATP III). Results: Dietary cholesterol was in line with serum TC, LDL-C and the LDL-C to HDL-C ratio in general and the partial correlation coefficients were 0.64 (95% CI: 0.13–1.15, p = 0.015), 0.73 (95% CI: 0.21–1.24, p = 0.006) and 0.01 (95% CI: 0.00–0.02, p = 0.018), respectively. The partial correlation coefficients were greater in women. Dietary fatty acids were not associated with serum lipids. The highest quintile of dietary cholesterol intake (≥538.0 mg/day) was associated with an approximate 1.6-fold risk for high TC and high HDL-C compared with the lowest quintile (<193.1 mg/day) generally. Conclusions: Dietary cholesterol was associated with serum cholesterol in Chinese metropolitan adults and a higher risk of dyslipidemia was observed at a high level of dietary cholesterol intake. Whether there should be an upper limit on dietary cholesterol in the Chinese population warrants further study.

CONCENTRATIONS AND FATTY ACID COMPOSITION OF SERUM LIPIDS FOLLOWING SERIOUS COMPLICATING ILLNESS IN HYPOTHYROIDISM

1972 ◽  
Vol 71 (1) ◽  
pp. 80-85 ◽  
Author(s):  
Knut Kirkeby
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Linoleic Acid ◽  
Acid Composition ◽  
Serum Cholesterol ◽  
Serum Lipids ◽  
Acute Illness ◽  
Unknown Factor ◽  
Hypothyroid Patients ◽  
Made In

ABSTRACT Studies on serum lipids and their fatty acid composition have been carried out in 3 patients with untreated hypothyroidism, who also suffered from acute complicating diseases. It was found that the hypothyroid patients reacted to the acute complicating disease in the same way as euthyroid subjects, i. e. with a lowering of serum cholesterol and phospholipids, and disturbances in fatty acid composition. Very low values of linoleic acid percentages were found following one week of complicating disease, contrary to findings made in hypothyroid patients without any complicating diseases. The changes in fatty acid composition indicate a very active re-synthesis of lipoproteins. It is suggested that the unknown factor responsible for lipoprotein degradation in acute illness also activates their re-synthesis, since the formation and turnover of lipoproteins in hypothyroidism are usually low.

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