Urinary hydroxyproline excretion and vitamin C status in healthy young men

1. Blood flow to the skeleton was measured by the 18F clearance method of Wootton, Reeve & Veall (1976) in 24 patients with untreated Paget's disease. In every patient but one, resting skeletal blood flow was increased. There was a significant positive correlation between skeletal blood flow and serum alkaline phosphatase and between skeletal blood flow and urinary total hydroxyproline excretion. 2. Fourteen patients were re-studied after they had received short-term (7 days or less) or long-term (7 weeks or more) calcitonin. Skeletal blood flow, alkaline phosphatase and urinary hydroxyproline excretion fell towards normal in every case. There was some evidence from the short-term studies that calcitonin produced a more rapid fall in skeletal blood flow than in alkaline phosphatase. 3. Glomerular filtration rate appeared to increase transiently in response to calcitonin.

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Diagnostic accuracy of urinary indices to detect mild dehydration in young men following acute riboflavin, Vitamin C or beetroot supplementation

Clinical Nutrition ESPEN ◽

10.1016/j.clnesp.2020.03.006 ◽

2020 ◽

Vol 37 ◽

pp. 129-133

Author(s):

Brandon A. Yates ◽

Lindsay A. Ellis ◽

Colleen X. Muñoz ◽

Lawrence E. Armstrong

Keyword(s):

Vitamin C ◽

Diagnostic Accuracy ◽

Young Men

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Plasma Somatomedin Activity and Urinary Hydroxyproline Excretion during Administration of Human Growth Hormone in Children with Short Stature

Hormone Research ◽

10.1159/000179890 ◽

1984 ◽

Vol 19 (4) ◽

pp. 205-215 ◽

Cited By ~ 3

Author(s):

J.M. Wit ◽

Van den Brande

Keyword(s):

Growth Hormone ◽

Short Stature ◽

Human Growth Hormone ◽

Human Growth ◽

Urinary Hydroxyproline ◽

Hydroxyproline Excretion

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Effect of Salmon Calcitonin on Cardiac Output, Oxygen Transport and Bone Turnover in Patients with Paget's Disease

Clinical Science ◽

10.1042/cs0480537 ◽

1975 ◽

Vol 48 (6) ◽

pp. 537-540 ◽

Cited By ~ 1

Author(s):

W. A. Crosbie ◽

S. M. Mohamedally ◽

N. J. Y. Woodhouse

Keyword(s):

Cardiac Output ◽

Pain Relief ◽

Oxygen Transport ◽

Salmon Calcitonin ◽

Bone Pain ◽

Paget’S Disease ◽

Paget's Disease ◽

Urinary Hydroxyproline ◽

The Mean ◽

Hydroxyproline Excretion

1. Twelve patients with symptomatic Paget's disease were studied before starting treatment with salmon calcitonin (12.5 μg) subcutaneously twice daily. Eleven of them were studied again after 3 months on this therapy. 2. Although pretreatment values for urinary total hydroxyproline excretion and cardiac output were considerably increased in some patients, there was no correlation between these two variables in the group as a whole. 3. Treatment resulted in a striking reduction in disease activity; the mean urinary hydroxyproline decreased 67%. 4. There was, however, no significant fall in cardiac output or change in oxygen transport during treatment. 5. Of the eight patients with bone pain who received treatment, five claimed complete pain relief.

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