scholarly journals Validity of the relative-dose-response test and the modified-relative-dose-response test as indicators of vitamin A stores in liver

2005 ◽  
Vol 81 (4) ◽  
pp. 835-839 ◽  
Author(s):  
Hans Verhoef ◽  
Clive E West
Keyword(s):  
Vitamin A ◽  
Dose Response ◽  
Response Test ◽  
Modified Relative Dose Response

scholarly journals Vitamin A intake and infection are associated with plasma retinol among pre-school children in rural Zambia

2012 ◽  
Vol 15 (9) ◽  
pp. 1688-1696 ◽  
Author(s):  
Christine Hotz ◽  
Justin Chileshe ◽  
Ward Siamusantu ◽  
Uma Palaniappan ◽  
Emmanuel Kafwembe
Keyword(s):  
Vitamin A ◽  
Dose Response ◽  
Acute Phase Proteins ◽  
Vitamin A Deficiency ◽  
Dietary Vitamin ◽  
Response Test ◽  
Post Harvest ◽  
Vitamin A Status ◽  
Plasma Retinol ◽  
Modified Relative Dose Response

AbstractObjectiveTo determine the prevalence of vitamin A deficiency, infection and adequacy of vitamin A intakes among Zambian children, and the contribution of dietary vitamin A and infection to vitamin A status.DesignA cross-sectional survey of vitamin A intakes by the 24 h recall method, vitamin A status by plasma retinol and the modified relative dose-response test, and infection by acute-phase proteins.SettingRural communities in Central and Eastern Provinces of Zambia.SubjectsChildren 2–5 years of age.ResultsThe prevalence of vitamin A deficiency was 56 % by plasma retinol, 48 % with infection-adjusted plasma retinol and 22 % by the modified relative dose-response test. The majority of children (61 %) had a current infection. Vitamin A intakes were relatively high (331 to 585 μg retinol activity equivalents/d in the harvest/early post-harvest and late post-harvest seasons, respectively) and the prevalence of inadequate intakes was <1 % when compared with the Estimated Average Requirement (210 and 275 μg retinol activity equivalents/d for children aged 1–3 and 4–8 years, respectively). Elevated α-1-acid glycoprotein was negatively associated with plasma retinol (P< 0·0 0 1) and vitamin A intake was positively associated with plasma retinol (P< 0·05), but only when estimated assuming a 26:1 retinol equivalence for provitamin A from green and yellow vegetables.ConclusionsInfection and vitamin A intakes were significant determinants of plasma retinol. We cannot conclude which indicator more accurately represents the true vitamin A status of the population. Reasons for the persistent high prevalence of vitamin A deficiency in the presence of adequate vitamin A intakes are unclear, but the high rates of infection may play a role.

scholarly journals Evaluation of vitamin A supplementation regimens in Ghanaian postpartum mothers with the use of the modified-relative-dose-response test

2006 ◽  
Vol 84 (6) ◽  
pp. 1344-1349 ◽  
Author(s):  
Samuel K Tchum ◽  
Sherry A Tanumihardjo ◽  
Samuel Newton ◽  
Bruno de Benoist ◽  
Seth Owusu-Agyei ◽  
...  
Keyword(s):  
Vitamin A ◽  
Dose Response ◽  
Vitamin A Supplementation ◽  
Response Test ◽  
Postpartum Mothers ◽  
Modified Relative Dose Response

scholarly journals Improved Method for Measurement of Retinol and Didehydroretinol in the Modified Relative Dose Response Test to Detect Vitamin A Deficiency

2003 ◽  
Vol 49 (2) ◽  
pp. 338-339 ◽  
Author(s):  
Juergen G Erhardt ◽  
Hans K Biesalski ◽  
Lucie C Malaba ◽  
Neal E Craft
Keyword(s):  
Vitamin A ◽  
Dose Response ◽  
Vitamin A Deficiency ◽  
Improved Method ◽  
Response Test ◽  
Modified Relative Dose Response

scholarly journals High Prevalence of Vitamin A Deficiency Is Detected by the Modified Relative Dose-Response Test in Six-Month-Old Senegalese Breast-Fed Infants

2012 ◽  
Vol 142 (11) ◽  
pp. 1991-1996 ◽  
Author(s):  
Anta Agne-Djigo ◽  
Nicole Idohou-Dossou ◽  
Komlan M. Kwadjode ◽  
Sherry A. Tanumihardjo ◽  
Salimata Wade
Keyword(s):  
Vitamin A ◽  
Dose Response ◽  
Vitamin A Deficiency ◽  
Response Test ◽  
High Prevalence ◽  
Breast Fed ◽  
Modified Relative Dose Response

scholarly journals Refinement of the modified-relative-dose-response test as a method for assessing vitamin A status in a field setting: experience with Indonesian children

1996 ◽  
Vol 64 (6) ◽  
pp. 966-971 ◽  
Author(s):  
S A Tanumihardjo ◽  
J C Cheng ◽  
D Permaesih ◽  
Muherdiyantiningsih ◽  
E Rustan ◽  
...  
Keyword(s):  
Vitamin A ◽  
Dose Response ◽  
Response Test ◽  
Vitamin A Status ◽  
Field Setting ◽  
Modified Relative Dose Response

Vitamin A status in preschool-age Indonesian children as assessed by the modified relative-dose-response assay

1990 ◽  
Vol 52 (6) ◽  
pp. 1068-1072 ◽  
Author(s):  
S A Tanumihardjo ◽  
Muhilal ◽  
Y Yuniar ◽  
D Permaesih ◽  
Z Sulaiman ◽  
...  
Keyword(s):  
Vitamin A ◽  
Dose Response ◽  
Preschool Age ◽  
Vitamin A Status ◽  
Modified Relative Dose Response

Vitamin A relative dose response test: validation by intravenous injection in children with liver disease

1987 ◽  
Vol 46 (2) ◽  
pp. 286-289 ◽  
Author(s):  
O Amedee-Manesme ◽  
M S Mourey ◽  
A Hanck ◽  
J Therasse
Keyword(s):  
Liver Disease ◽  
Vitamin A ◽  
Intravenous Injection ◽  
Dose Response ◽  
Test Validation ◽  
Response Test

scholarly journals β-Carotene–rich orange-fleshed sweet potato improves the vitamin A status of primary school children assessed with the modified-relative-dose-response test

2005 ◽  
Vol 81 (5) ◽  
pp. 1080-1087 ◽  
Author(s):  
Paul J van Jaarsveld ◽  
Mieke Faber ◽  
Sherry A Tanumihardjo ◽  
Penelope Nestel ◽  
Carl J Lombard ◽  
...  
Keyword(s):  
Vitamin A ◽  
Primary School ◽  
Sweet Potato ◽  
School Children ◽  
Dose Response ◽  
Primary School Children ◽  
Response Test ◽  
Vitamin A Status ◽  
Orange Fleshed Sweet Potato ◽  
Β Carotene
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