scholarly journals Effect of low-fat, fermented milk enriched with plant sterols on serum lipid profile and oxidative stress in moderate hypercholesterolemia

2007 ◽  
Vol 86 (3) ◽  
pp. 790-796 ◽  
Author(s):  
Boris Hansel ◽  
Catherine Nicolle ◽  
Florent Lalanne ◽  
Françoise Tondu ◽  
Taous Lassel ◽  
...  
2004 ◽  
Vol 58 (6) ◽  
pp. 860-870 ◽  
Author(s):  
A B Thomsen ◽  
H B Hansen ◽  
C Christiansen ◽  
H Green ◽  
A Berger

2003 ◽  
Vol 28 (1) ◽  
pp. 1-5 ◽  
Author(s):  
N. H. Ugochukwu ◽  
N. E. Babady ◽  
M. Cobourne ◽  
S. R. Gasset

2019 ◽  
Vol 14 (1) ◽  
pp. 54-58
Author(s):  
Samia Haque Tonu ◽  
Jasmine Fauzia Dewan ◽  
Nargis Akhter ◽  
Md Enamul Haque ◽  
Md Abdul Wahab

Introduction: Hyperlipidemia is a major risk for the development of atherosclerosis leading to cardiovascular complications. Atorvastatin and rosuvastatin are two widely used important members of the HMG-CoA reductase inhibitor (statins). The beneficial effects of statins on clinical events also involve lipid-independent mechanisms which include improvement of oxidative stress status. Objective: To compare the antioxidative effect of atorvastatin and rosuvastatin in patients with hyperlipidemia. Materials and Methods: A prospective randomized single-center analytic study was carried out in Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka from March 2016 to August 2017 on 52 hyperlipidemic patients. After randomization patients were assigned to atorvastatin 10 mg or rosuvastatin 5 mg daily for 8 weeks. Blood was collected at baseline and after the intervention to measure plasma malondialdehyde (MDA), erythrocyte reduced glutathione (GSH) (as biomarkers of oxidative stress) and serum lipid profile. Results: The baseline characteristics of patients treated with atorvastatin and rosuvastatin were almost identical. The level of plasma MDA in atorvastatin (1.35 ± 0.94 to 0.97± 0.64) and rosuvastatin (1.56±0.69 to 0.98±0.38) group was significantly reduced after intervention (28.15%, p<0.05 and 37.18%, p<0.001 respectively) but no statistically significant difference (p>0.05) was observed between the two statin-treated groups. Erythrocyte GSH level was increased after intervention in both atorvastatin (2.43±2.90 to 4.14 ± 4.87) group (70.37%, p<0.01) and rosuvastatin (2.76±3.80 to 8.36±12.93)  group (202.90%, p<0.01), which was statistically significant. No significant difference was observed between the two groups (p>0.05). Both atorvastatin and rosuvastatin significantly improved serum lipid profile. Conclusion: Both atorvastatin and rosuvastatin significantly improved oxidative stress status in hyperlipidemic patients but no significant change was observed between the two statin-treated groups. Journal of Armed Forces Medical College Bangladesh Vol.14(1) 2018: 54-58


2021 ◽  
Vol 23 ◽  
pp. 100336
Author(s):  
Peter Ifeoluwa Adegbola ◽  
Olumide Samuel Fadahunsi ◽  
Bamidele Stephen Ajilore ◽  
Adebola Olayemi Akintola ◽  
Olubukola Sinbad Olorunnisola

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