Nuclear DNA Content as a Prognostic Factor in T1−2N0 Breast Cancer

1990 ◽  
Vol 93 (4) ◽  
pp. 471-479 ◽  
Author(s):  
Sakari Toikkanen ◽  
Heikki Joensuu ◽  
Pekka Klemi
1989 ◽  
Vol 13 (1) ◽  
pp. 23-32 ◽  
Author(s):  
Anette von Rosen ◽  
Lars Erik Rutqvist ◽  
John Carstensen ◽  
Anders Fallenius ◽  
Lambert Skoog ◽  
...  

1987 ◽  
Vol 9 (2) ◽  
pp. 101-109 ◽  
Author(s):  
Jennet Harvey ◽  
Nicholas de Klerk ◽  
Ian Berryman ◽  
Gregory Sterrett ◽  
Michael Byrne ◽  
...  

1997 ◽  
Vol 30 (1) ◽  
pp. 15-19
Author(s):  
Atsuo Tsuchiya ◽  
Youichi Kikuchi ◽  
Rikiya Abe ◽  
Hiroshi Mizunuma ◽  
Masashi Kanazawa ◽  
...  

1992 ◽  
Vol 31 (4) ◽  
pp. 591-598
Author(s):  
Takashi HIRANO ◽  
Takahisa KITO ◽  
Norihiko IKEDA ◽  
Osamu UCHIDA ◽  
Toichiro KATSUMI ◽  
...  

1997 ◽  
Vol 13 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Sudip Sarker ◽  
Allan Spigelman ◽  
Marjorie Walker ◽  
Dulcie Coleman

Patients with aggressive breast cancers benefit from chemotherapy prior to surgery. If the biology of the breast cancers were better characterised pre‐operatively, more patients at risk could be offered chemotherapy. We have assessed nuclear DNA content of fine needle aspirates (FNA) of 103 invasive ductal breast cancers and compared this to tumour size, node status and histological grade. Median follow‐up was 18 months so no prognostic studies were made. Diploid and non‐diploid tumours were distributed equally in node negative and positive patients. However non‐diploidy status increased in line with known prognostic markers of tumour size and histological grade. This suggests that ploidy might contribute to the pre‐operative assessment of prognosis. We conclude that nuclear DNA of breast cancer FNAs may be of value in the pre‐operative biological assessment of breast cancer patients.


Cytometry ◽  
1989 ◽  
Vol 10 (1) ◽  
pp. 56-61 ◽  
Author(s):  
J. C. Van Der Linden ◽  
J. Lindeman ◽  
J. P. A. Baak ◽  
C. J. L. M. Meijer ◽  
C. J. Herman

1988 ◽  
Vol 12 (4) ◽  
pp. 503-507 ◽  
Author(s):  
Jaap F. Hamming ◽  
Lodewijk J. D. M. Schelfhout ◽  
Cees J. Cornelisse ◽  
Cornelis J. H. van de Velde ◽  
Bernard M. Goslings ◽  
...  

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