scholarly journals Acute Myeloid Leukemia with Extensive Bone Marrow Necrosis

2014 ◽  
Vol 25 ◽  
pp. v84 ◽  
Author(s):  
Takayo Ota ◽  
Tsunayuki Kakimoto ◽  
Toshiharu Tamaki
2015 ◽  
Vol 8 (2) ◽  
pp. 345-348 ◽  
Author(s):  
Roman Shapiro ◽  
Kamilia Rizkalla ◽  
Selay Lam

Extensive necrosis affecting more than 50% of the bone marrow is an extremely rare histopathological finding. Relatively little is known about its clinical significance because it is most commonly identified at autopsy - whether it is an independent prognostic marker or whether it is a surrogate marker of underlying disease burden remains unclear. We describe herein a case of a 66-year-old patient with acute myeloid leukemia who presented with acute bone marrow failure and was found to have extensive necrosis. We include presenting clinical features, pathology attained at biopsy, and the challenge of treatment. Bone marrow necrosis is a rare but important clinicopathological entity whose recognition may herald the way for more effective prognostication of underlying disease.


2007 ◽  
Vol 82 (11) ◽  
pp. 1029-1029 ◽  
Author(s):  
Pieter Vermeersch ◽  
Pierre Zachee ◽  
Caroline Brusselmans

2011 ◽  
Vol 86 (5) ◽  
pp. 451-452 ◽  
Author(s):  
Aleksandar Radujkovic ◽  
Frauke Bellos ◽  
Mindaugas Andrulis ◽  
Anthony D. Ho ◽  
Michael Hundemer

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