scholarly journals First-in-human phase I study of copanlisib (BAY 80-6946), an intravenous pan-class I phosphatidylinositol 3-kinase inhibitor, in patients with advanced solid tumors and non-Hodgkin's lymphomas

2016 ◽  
Vol 27 (10) ◽  
pp. 1928-1940 ◽  
Author(s):  
A. Patnaik ◽  
L.J. Appleman ◽  
A.W. Tolcher ◽  
K.P. Papadopoulos ◽  
M. Beeram ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Phase I Study ◽  
Kinase Inhibitor ◽  
Class I ◽  
Advanced Solid Tumors ◽  
Phosphatidylinositol 3 Kinase ◽  
Hodgkin's Lymphomas ◽  
Phosphatidylinositol 3

scholarly journals A Multicenter Phase I Trial of PX-866, an Oral Irreversible Phosphatidylinositol 3-Kinase Inhibitor, in Patients with Advanced Solid Tumors

2012 ◽  
Vol 18 (15) ◽  
pp. 4173-4182 ◽  
Author(s):  
David S. Hong ◽  
Daniel W. Bowles ◽  
Gerald S. Falchook ◽  
Wells A. Messersmith ◽  
Goldy C. George ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Phase I Trial ◽  
Kinase Inhibitor ◽  
Advanced Solid Tumors ◽  
Phosphatidylinositol 3 Kinase ◽  
Multicenter Phase ◽  
Phosphatidylinositol 3

scholarly journals Phase I Study of Bosutinib, a Src/Abl Tyrosine Kinase Inhibitor, Administered to Patients with Advanced Solid Tumors

2011 ◽  
Vol 18 (4) ◽  
pp. 1092-1100 ◽  
Author(s):  
Adil I. Daud ◽  
Smitha S. Krishnamurthi ◽  
Mansoor N. Saleh ◽  
Barbara J. Gitlitz ◽  
Mitesh J. Borad ◽  
...  
Keyword(s):  
Tyrosine Kinase ◽  
Phase I ◽  
Tyrosine Kinase Inhibitor ◽  
Solid Tumors ◽  
Phase I Study ◽  
Kinase Inhibitor ◽  
Advanced Solid Tumors ◽  
Abl Tyrosine Kinase ◽  
Abl Tyrosine Kinase Inhibitor

A phase I study of MK-5108, an oral aurora A kinase inhibitor, in both monotherapy and in combination with docetaxel in patients with advanced solid tumors.

2010 ◽  
Vol 28 (15_suppl) ◽  
pp. e13026-e13026 ◽  
Author(s):  
S. E. Minton ◽  
P. LoRusso ◽  
A. C. Lockhart ◽  
M. Saif ◽  
S. S. Krishnamurthi ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Phase I Study ◽  
Kinase Inhibitor ◽  
Advanced Solid Tumors ◽  
Aurora A Kinase ◽  
Aurora A

scholarly journals Phase I Study of Decitabine in Combination with Vorinostat in Patients with Advanced Solid Tumors and Non-Hodgkin's Lymphomas

2011 ◽  
Vol 17 (6) ◽  
pp. 1582-1590 ◽  
Author(s):  
Anastasios Stathis ◽  
Sebastien J. Hotte ◽  
Eric X. Chen ◽  
Holger W. Hirte ◽  
Amit M. Oza ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Phase I Study ◽  
Advanced Solid Tumors ◽  
Hodgkin's Lymphomas
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