EP.WE.1048Weight Regain After Sleeve Gastrectomy More Common in Male and Less Common in Super-Obese Patients - Results of an 18-Month Follow-up Study

2021 ◽  
Vol 108 (Supplement_7) ◽  
Author(s):  
Ahmed Salman Bodla ◽  
Jenny Abraham ◽  
Neha Shah ◽  
Vinod Menon

Abstract Aims Long-term success of Sleeve Gastrectomy (SG) is undermined by weight regain (WR). Several procedure- and patient-specific factors have been proposed in previous studies. Here we look at 18-month follow-up post-SG to investigate WR and patient-specific variables influencing this. Methods A single-centre study involving retrospective analysis of a prospectively-maintained database. Inclusion criteria: Primary non-revisional SG patients with adequate follow-up data to assess WL/WR trends. Patients were divided into two subgroups based on their %EWL between 6-to-12 and 12-to-18 months: weight regainers (WR) and weight losers/maintainers (WL/M). Results Out of 338 SG cases between 2012-2017, 180 met inclusion criteria of which 18.3% were men and 45% were super-obese. All patients lost weight during first 6 months (mean %EWL 52.3%, P < 0.0001). Between 6-to-12 months, 87.6% patients continued WL with a further mean %EWL of 10.35% (P < 0.0001). Between 12-to-18 months, a drastic deceleration/reversal of WL progress was observed with an average of only 0.76% EWL (P = 0.84), with 42% of patients regaining weight in this period (mean EWG 6.8%). Male patients encountered significantly higher WR rate (OR 3.27, P = 0.003), whereas it was much less frequent in pre-operatively super-obese patients (OR 0.48, P = 0.036). Moreover, there was no difference in the 6-month %EWL between WR and WL/M subgroups (P = 0.62), thus negating the possibility of WL burn-out phenomenon. Conclusions Different rates of WR in men and super-obese patients may indicate underlying behavioural and biological differences. More research is needed to investigate them in detail, having implications for revisional surgery and follow-up support.

2019 ◽  
Vol 15 (1) ◽  
pp. 23-33 ◽  
Author(s):  
Konstantinos Arapis ◽  
Nicoletta Macrina ◽  
Diana Kadouch ◽  
Lara Ribeiro Parenti ◽  
Jean Pierrre Marmuse ◽  
...  

2008 ◽  
Vol 02 (01) ◽  
pp. 11-18
Author(s):  
G. Weigand ◽  
S. Weiner ◽  
S. Theodoridou ◽  
I. Pomhoff ◽  
R. A. Weiner

ZusammenfassungDie Zunahme der morbiden Adipositas und insbesondere der extremen Formen (super-obese patients) mit einem BMI >50 kg/m2 verlangt nach einer operativen Behandlung und der Suche nach Verfahren, die in diesen Fällen eine Gewichtsreduktion mit niedriger Morbidität erlauben. Die Schlauchmagenbildung (SMB; engl.: sleeve gastrectomy [SG]) war ursprünglich zur biliopankreatischen Diversion (BPD) und dann zum Duodenalswitch (DS) im Jahre 1988 hinzugefügt worden. Erstmalig wurde die SG 1999 als Teil des DS und dann eigenständig 2000 laparoskopisch durchgeführt. Mit der Erfahrung des Gewichtsverlusts bei den ersten Patienten stieg das Interesse an diesem Verfahren als eigenständige OP. Vorteile der SMB wurden gesehen in der niedrigen Komplikationsrate, der Vermeidung von Implantaten, der Aufrechterhaltung der physiologischen Nahrungspassage, der Vermeidung einer Malabsorption und der Möglichkeit der Konversion zu allen anderen OPVerfahren. Die Reduktion der Ghrelin-produzierenden Magenmasse kann eine Ursache für eine Überlegenheit gegenüber allen anderen pur restriktiven Verfahren darstellen. Ungeachtet dessen sind Langzeitstudien notwendig, um die SMB als eigenständige bariatrische OP einzuführen, wie sie sich bereits im Stufenkonzept für Hochrisikopatienten als erster Schritt, gefolgt von einem Magenbypass oder DS, etabliert hat. Die Zwei-Schritt-Therapie der SMB mit nachfolgendem Magenbypass oder BPD ist sicher und effektiv. Die Effizienz der SMB für Patienten mit einem BMI <50 kg/m2 und die Inzidenz von Dilatationen des Magenschlauches sind noch nicht ausreichend untersucht. Die postoperative Morbidität und Mortalität sind noch nicht endgültig ermittelt und möglicherweise auf die noch nicht standardisierte operative Technik zurückzuführen. Der Verlust an Übergewicht ist signifikant größer, wenn eine Kalibration des Schlauchmagens vorgenommen wurde. Ein entferntes Magenvolumen <500 ml scheint mit einem potenziellen erneuten Gewichtsanstieg verbunden zu sein. Die SMB kann sicher und mit guten Ergebnissen hinsichtlich Gewichtsverlust und Lebensqualität in ein bariatrisches Programm integriert werden. Die SMB kann den ersten Schritt vor einem Magenbypass oder DS darstellen, bei guten Langzeitergebnissen auch ein singuläres Verfahren sein. Die OP-Methode sollte als eine chirurgische Option eingeführt und ihre exakte Anwendung durch weitere Studien definiert werden. Nachuntersuchungen werden notwendig sein, um die Langzeitergebnisse zu evaluieren.


2016 ◽  
Vol 12 (3) ◽  
pp. 541-549 ◽  
Author(s):  
Alper Celik ◽  
Eylem Cagiltay ◽  
Surendra Ugale ◽  
Muharrem Asci ◽  
Bahri Onur Celik ◽  
...  

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Alaa Abbas Sabry ◽  
Karim Sabry Abd-Elsamee ◽  
Mohamed Ibrahim Mohamed ◽  
Mohammed Mohamed Ahmed Abd-Elsalam

Abstract Background It is already known that Laparoscopic sleeve gastrectomy (LSG) has gained popularity as a stand-alone procedure with good short-term results for weight loss. However, in the long-term, weight regain is considered as a complication. Demand for secondary surgery is rising, partly for this reason, but through that study we try to discover the efficacy of conversion of failed sleeve gastrectomy to one anastomosis gastric bypass (OAGB) regarding weight loss and metabolic outcomes. Objective To asses the efficacy and safety of one anastomosis gastric bypass (OAGB) as a conversion surgery post Sleeve Gastrectomy failure as regard weight loss and metabolic outcomes. Patients and Methods This study is a retrospective cohort study which included 20 patients underwent one anastomosis gastric bypass at Ain-Shams University El-Demerdash Hospital, Cairo, Egypt and specialized bariatric center, Cairo, Egypt From February 2019 to July 2019 with 6 months of postoperative follow up till January 2019. Results In this study, we reviewed and analyzed the outcomes from the revision of the SG due to either inadequate weight loss or weight regain to one anastomosis gastric bypass (OAGB) with %EBWL of 6.65% at 1 month, 13.61 % at 3 months and 20.86% at 6 months. Conclusion OAGB appears to be an effective and safe therapeutic technique as a revisional surgery for failed primary SG with good short-term results for treating morbid obesity and its associated comorbidities with a significantly low rate of complications. However the EBWL was less than what is reported after primary OAGB weight. Multicenter studies with larger series of patients and longer term follow up after SG revisions to OAGB are warranted.


2018 ◽  
Vol 28 (3) ◽  
pp. 256-262 ◽  
Author(s):  
Vitish Singla ◽  
Sandeep Aggarwal ◽  
Harshit Garg ◽  
Lokesh Kashyap ◽  
Dilip R. Shende ◽  
...  

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Andrea Balla ◽  
Silvia Quaresima ◽  
Pietro Ursi ◽  
Ardit Seitaj ◽  
Livia Palmieri ◽  
...  

Introduction. In obese patients with hiatal hernia (HH), laparoscopic sleeve gastrectomy (LSG) with cruroplasty is an option but use of prosthetic mesh crura reinforcement is debated. The aim was to compare the results of hiatal closure with or without mesh buttressing during LSG. Methods. Gastroesophageal reflux disease (GERD) was assessed by the Health-Related Quality of Life (GERD-HRQL) questionnaire before and after surgery in two consecutive series of patients with esophageal hiatus ≤ 4 cm2. After LSG, patients in group A (12) underwent simple cruroplasty, whereas in group B patients (17), absorbable mesh crura buttressing was added. Results. At mean follow-up of 33.2 and 18.1 months for groups A and B, respectively (p=0.006), the mean preoperative GERD-HRQL scores of 16.5 and 17.7 (p=0.837) postoperatively became 9.5 and 2.4 (p=0.071). In group A, there was no difference between pre- and postoperative scores (p=0.279), whereas in group B, a highly significant difference was observed (p=0.002). The difference (Δ) comparing pre- and postoperative mean scores between the two groups was significantly in favor of mesh placement (p=0.0058). Conclusions. In obese patients with HH and mild-moderate GERD, reflux symptoms are significantly improved at medium term follow-up after cruroplasty with versus without crura buttressing during LSG.


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