scholarly journals Kv1.3 inhibition as a potential microglia-targeted therapy for Alzheimer’s disease: preclinical proof of concept

Brain ◽  
2017 ◽  
Vol 141 (2) ◽  
pp. 596-612 ◽  
Author(s):  
Izumi Maezawa ◽  
Hai M Nguyen ◽  
Jacopo Di Lucente ◽  
David Paul Jenkins ◽  
Vikrant Singh ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Targeted Therapy ◽  
Proof Of Concept

P3-214: Alzheimer's disease identification using amyloid imaging and reserve variables: Proof of concept

2010 ◽  
Vol 6 ◽  
pp. S513-S513
Author(s):  
Catherine M. Roe ◽  
Mark A. Mintun ◽  
Nupur Ghoshal ◽  
Monique M. Williams ◽  
Elizabeth A. Grant ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Amyloid Imaging ◽  
Proof Of Concept ◽  
Disease Identification

P4-164: Aβ oligomers as tractable drug targets in Alzheimer's disease: in vivo proof of concept for the oligomer-binding small-molecule therapeutic candidate cbb68

2015 ◽  
Vol 11 (7S_Part_18) ◽  
pp. P841-P842
Author(s):  
Armand W.J.W. Tepper ◽  
Elizabeth C. de Boer ◽  
Emily Hoogveld ◽  
Joost D.J. Vis ◽  
Ivar C. Schut ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Small Molecule ◽  
Drug Targets ◽  
Proof Of Concept ◽  
Aβ Oligomers
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