FLow-injection analysis: a new approach to quantitative measurements in clinical chemistry.

1982 ◽  
Vol 28 (3) ◽  
pp. 409-421 ◽  
Author(s):  
B Rocks ◽  
C Riley
Keyword(s):  
Flow Injection ◽  
Flow Injection Analysis ◽  
Clinical Chemistry ◽  
Flow Analysis ◽  
New Approach ◽  
Quantitative Measurements ◽  
Continuous Flow Analysis ◽  
Carrier Stream ◽  
Analysis System ◽  
Analytical Requirements

Abstract Flow-injection analysis, founded on an approach that is entirely different from continuous-flow analysis, involves use of three principles: sample "injection," controlled dispersion of sample (rather than a dispersion retarded with gas bubbles), and reproducible timing. The conditions governing the dispersion of the sample in the flowing carrier stream are considered, and we illustrate how the dispersion can be manipulated to suit particular analytical requirements. Instrumentation and practical aspects of flow-injection analyses are discussed, especially with regard to clinical chemistry applications, and the technique is compared with the more conventional gas-segmented-flow analysis system. We conclude that, because of its speed, economy, and simplicity, flow-injection analysis will eventually replace the gas-segmented approach for many clinical chemistry analyses.

scholarly journals The role of flow injection analysis within the framework of an automated laboratory

1990 ◽  
Vol 12 (3) ◽  
pp. 95-103 ◽  
Author(s):  
Peter B. Stockwell
Keyword(s):  
Flow Injection ◽  
Flow Injection Analysis ◽  
Flow Analysis ◽  
Research Groups ◽  
Market Place ◽  
Advantages And Disadvantages ◽  
Considerable Success ◽  
Continuous Flow Analysis ◽  
Commercial Market

Flow Injection Analysis (FIA) was invented at roughly the same time by two quite dissimilar research groups [1,2]. FIA was patented by both groups in 1974; a year also marked by the publication of the first book on automatic chemical analysis [3]. This book was a major undertaking for its authors and it is hoped that it has added to the knowledge of those analysts attempting to automate their work or to increase the level of computerization/automation and thus reduce staffing commitments. This review discusses the role of FIA in laboratory automation, the advantages and disadvantages of the FIA approach, and the part it could play in future developments.It is important to stress at the outset that the FIA approach is all too often closely paralleled with convention al continuous flow analysis (CFA). This is a mistake for many reasons, none the least of which because of the considerable success of the CFA approach in contrast to the present lack of penetration in the commercial market-place of FIA instrumentation.

Flow Injection Analysis System forl-Lysine Estimation in Foodstuffs Using a Biosensor Based on Lysine Oxidase Immobilization on a Gold-Poly(m-Phenylenediamine) Electrode

2003 ◽  
Vol 36 (9) ◽  
pp. 1939-1963 ◽  
Author(s):  
Maria H. Divritsioti ◽  
Ioannis D. Karalemas ◽  
Constantinos A. Georgiou ◽  
Demetrius S. Papastathopoulos
Keyword(s):  
Flow Injection ◽  
Flow Injection Analysis ◽  
Flow Injection Analysis System ◽  
Analysis System ◽  
Lysine Oxidase
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