scholarly journals Positional Cloning Identifies Lotus japonicus NSP2, A Putative Transcription Factor of the GRAS Family, Required for NIN and ENOD40 Gene Expression in Nodule Initiation

DNA Research ◽  
2006 ◽  
Vol 13 (6) ◽  
pp. 255-265 ◽  
Author(s):  
Y. Murakami ◽  
H. Miwa ◽  
H. Imaizumi-Anraku ◽  
H. Kouchi ◽  
J. A. Downie ◽  
...  
Keyword(s):  
Gene Expression ◽  
Transcription Factor ◽  
Positional Cloning ◽  
Lotus Japonicus ◽  
Gras Family ◽  
Putative Transcription Factor ◽  
Nodule Initiation

scholarly journals Interspecies DNA Microarray Analysis Identifies WblA as a Pleiotropic Down-Regulator of Antibiotic Biosynthesis in Streptomyces

2007 ◽  
Vol 189 (11) ◽  
pp. 4315-4319 ◽  
Author(s):  
Seung-Hoon Kang ◽  
Jianqiang Huang ◽  
Han-Na Lee ◽  
Yoon-Ah Hur ◽  
Stanley N. Cohen ◽  
...  
Keyword(s):  
Gene Expression ◽  
Transcription Factor ◽  
Microarray Analysis ◽  
Dna Microarray ◽  
Antibiotic Production ◽  
Streptomyces Coelicolor ◽  
Morphological Differentiation ◽  
Antibiotic Biosynthesis ◽  
Gene Encoding ◽  
Putative Transcription Factor

ABSTRACT Using Streptomyces coelicolor microarrays to discover regulators of gene expression in other Streptomyces species, we identified wblA, a whiB-like gene encoding a putative transcription factor, as a down-regulator of doxorubicin biosynthesis in Streptomyces peucetius. Further analysis revealed that wblA functions pleiotropically to control antibiotic production and morphological differentiation in streptomycetes. Our results reveal a novel biological role for wblA and show the utility of interspecies microarray analysis for the investigation of streptomycete gene expression.

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