The clinical pharmacology of alinidine and its side-effects

1987 ◽  
Vol 8 (suppl L) ◽  
pp. 83-90 ◽  
Author(s):  
R. G. Shanks
Keyword(s):  
Clinical Pharmacology ◽  
Side Effects

Methotrexate Therapy in Obstetricaĺ Diseases

2016 ◽  
Vol 4 (1) ◽  
pp. 9 ◽  
Author(s):  
Aneta Tomescu ◽  
Rodica Sîrbu ◽  
Stelian Paris ◽  
Emin Cadar ◽  
Cristina Luiza Erimia ◽  
...  
Keyword(s):  
Clinical Pharmacology ◽  
Side Effects ◽  
Ectopic Pregnancy ◽  
Malignant Disease ◽  
Surgical Intervention ◽  
Hydatidiform Mole ◽  
Medical Abortion ◽  
Methotrexate Therapy ◽  
Therapeutic Effects ◽  
Neoplastic Diseases

Our study is a rewiew of Methotrexate therapy in obstetrica? diseases such us: hydatidiform mole, and medical abortion. In the medical world, methotrexate is a citostatic drug used in neoplastic diseases. The clinical pharmacology data regarding methotrexate is presented, alongside route of administration and therapeutic effects in malignant disease, hydatiform mole, and medical abortion. The use of methotrexate in medical abortion and ectopic pregnancy is a great accomplishment, as it replaces a surgical intervention marred by characteristic side effects, with similar results.

Methotrexate Therapy in Obstetricaĺ Diseases

2016 ◽  
Vol 2 (1) ◽  
pp. 9 ◽  
Author(s):  
Aneta Tomescu ◽  
Rodica Sîrbu ◽  
Stelian Paris ◽  
Emin Cadar ◽  
Cristina Luiza Erimia ◽  
...  
Keyword(s):  
Clinical Pharmacology ◽  
Side Effects ◽  
Ectopic Pregnancy ◽  
Malignant Disease ◽  
Surgical Intervention ◽  
Hydatidiform Mole ◽  
Medical Abortion ◽  
Methotrexate Therapy ◽  
Therapeutic Effects ◽  
Neoplastic Diseases

Our study is a rewiew of Methotrexate therapy in obstetrica? diseases such us: hydatidiform mole, and medical abortion. In the medical world, methotrexate is a citostatic drug used in neoplastic diseases. The clinical pharmacology data regarding methotrexate is presented, alongside route of administration and therapeutic effects in malignant disease, hydatiform mole, and medical abortion. The use of methotrexate in medical abortion and ectopic pregnancy is a great accomplishment, as it replaces a surgical intervention marred by characteristic side effects, with similar results.

Monoamine Agonists (“Antidepressants”), Including Dopamine Agonists (“Stimulants”)

2018 ◽  
pp. 85-100
Author(s):  
S. Nassir Ghaemi
Keyword(s):  
Clinical Pharmacology ◽  
Side Effects ◽  
Sexual Dysfunction ◽  
Drug Interactions ◽  
Psychotropic Drugs ◽  
Withdrawal Syndrome ◽  
Serotonin Reuptake ◽  
Dopamine Agonists ◽  
Serotonin Reuptake Inhibitors ◽  
Norepinephrine Reuptake

The drug class of monoamine agonists includes agents called antidepressants and stimulants. Monoamine agonists are the most widely used class of psychotropic drugs. There are three major monoamines, and thus three main types of monoamine agonists. We consider each in turn: the serotonin reuptake inhibitors (SRIs), norepinephrine reuptake inhibitors (NRIs), and dopaminergic agents. We also discuss the dopamine agonists—bupropion (Wellbutrin) and amphetamines (“stimulants”), as well as other new monoamine agonists. The clinical pharmacology of specific agents within each class, including their efficacy and side effects, is explored. Specific phenomena surveyed include SRI tolerance, sexual dysfunction, drug interactions, serotonin withdrawal syndrome, and suicide and akathisia.

Dopamine Blockers (“Antipsychotics”)

2018 ◽  
pp. 101-126
Author(s):  
S. Nassir Ghaemi
Keyword(s):  
Metabolic Syndrome ◽  
Clinical Pharmacology ◽  
Weight Gain ◽  
Side Effects ◽  
Tardive Dyskinesia ◽  
Drug Class ◽  
Acute Mania ◽  
Psychotic Symptoms ◽  
Extrapyramidal Side Effects ◽  
Bipolar Illness

The drug class of dopamine blockers includes agents called antipsychotics. It consists of dopamine blockers, often with serotonin blockade. Dopamine blockers are agents used to treat psychotic symptoms such as delusions and hallucinations. These medications have been developed mostly for use in schizophrenia, but they always have been found to be effective in acute mania as well. For the latter reason, they have been used in bipolar illness as well. Several of these agents have been proven effective in the depressive phase of bipolar illness, not just the manic phase. Also, some of them have been shown to be effective in the depressive phase of unipolar mood illness. The clinical pharmacology of specific agents within each class of dopamine blockers, including efficacy and side effects, is explored. Specific phenomena surveyed include metabolic syndrome, weight gain, extrapyramidal side effects, Parkinsonism, akathisia, and tardive dyskinesia.

scholarly journals Basic and Clinical Pharmacology of Autonomic Drugs

2012 ◽  
Vol 59 (4) ◽  
pp. 159-169 ◽  
Author(s):  
Daniel E. Becker
Keyword(s):  
Clinical Pharmacology ◽  
Nervous System ◽  
Autonomic Nervous System ◽  
Side Effects ◽  
Basic Function ◽  
Nervous Systems ◽  
Autonomic Nervous ◽  
Normal Functions ◽  
Drug Classes

Abstract Autonomic drugs are used clinically to either imitate or inhibit the normal functions of the sympathetic and parasympathetic nervous systems. A large number of additional drug classes also interact with these systems to produce a stunning number of possible side effects. This article reviews the basic function of the autonomic nervous system and the various drug classes that act within these neural synapses.

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