scholarly journals Stenting in the common femoral vein does not increase posthrombotic syndrome or rethrombosis

2021 ◽  
Vol 42 (Supplement_1) ◽  
Author(s):  
S Krause ◽  
J M J R Telayna ◽  
R A Costantini ◽  
J M Telayna
Keyword(s):  
Stent Placement ◽  
Femoral Vein ◽  
Iliac Vein ◽  
Female Population ◽  
Common Femoral Vein ◽  
Group A ◽  
The Common ◽  
Group B ◽  
Venous Stents

Abstract Background In lower limbs deep venous thrombosis (DVT) scenario there is evidence that favours catheter guided invasive treatment. The treatment with stenting in the common femoral vein could be related with a diminished permeability in the inflow of the deep femoral vein. There is scarce data of the clinical follow up of this treatment. Purpose To analize and compare clinical and procedural outcomes in endovenous interventions that required stent placement in the common femoral vein because of residual lesion vs interventions that did no require such treatment. Methods From May 2010 to December 2020, 122 endovenous interventions were performed, within these 74 were DVT compromising the iliofemoral territory. Two groups were defined: Group A 28 (38%) that required stent placement in the common femoral vein and Group B 46 (62%) that did not required such treatment. Results Baseline characteristics were Group A vs Group B n (%) respectively: Median age 41.1±16.7 vs 40.5±18.8; female 23 (82) vs 27 (58); smoking 7 (25) vs 14 (30); cancer 1 (4) vs 7 (15); prior prolonged rest 7 (25) vs 14 (30); concomitant diagnosis of pulmonary embolism 7 (25) vs 17 (37). Within the female population 2 (7) vs 1 (2) were in puerperium; 6 (21) vs 6 (13) were under contraceptive therapy. Regarding the diagnosis of DVT 21 (75) vs 37 (80) were acute; 7 (25) vs 9 (19) were chronic. Compromised vessels were primitive iliac vein 21 (75) vs 38 (82); external iliac vein 6 (21) vs 18 (39); superficial femoral vein 11 (39) vs 8 (17); May-Thurner syndrome 14 (50) vs 20 (43). As regards the aspects of the intervention 15 (53) vs 34 (74) had a filter implanted in the inferior vena cava; thrombolytics were infused in 20 (71) vs 32 (70); manual thrombectomy was performed in 8 (27) vs 17 (37); mechanical thrombectomy 11 (39) vs 19 (41); pre dilation with balloon was performed in 22 (79) vs 39 (85); dedicated venous stents were implanted in 22 (78) vs 39 (85); not dedicated venous stents in 13 (46) vs 11 (24). Technique success was achieved in 28 (100) vs 45 (98) p=1; major bleeding occurred 0 vs 2 (4) p=0.5; rethrombosis 3 (10) vs 9 (20) p=0.25; intrahospital death 1 (4) vs 2 (4) p=1; early reintervention was needed 1 (4) vs 2 (4) p=1, radiation dose (min) 35.4±20.2 vs 30.1±17.0 p=0.2; Contrast (ml) 216.5±76.8 vs 217.3±90.8 p=0.9. During follow up (34.1±31.5 vs 22.3±16.4) image control was performed in 27 (96) vs 39 (85) p=0.23 with either doppler or chest computed tomography angiography. Post thrombotic syndrome (PTS) symptoms were classified with Villalta Score assuming that 0–4 points had no PTS, 5–9 points presented mild PTS, 10–14 points moderate PTS, >14 points severe PTS, in Group A 1 (4) presented mild PTS vs Group B 2 (4) mild PTS p=1, 1 (2) moderate PTS. Conclusions Endovenous treatment with stent placement in the common femoral vein did not required more reinterventions nor had more complications nor had more PTS that the interventions without stent placement. FUNDunding Acknowledgement Type of funding sources: None. Table 1. Basal Characteristics Table 2. Outcomes

scholarly journals Endovenectomy of the common femoral vein and intraoperative iliac vein recanalization for chronic iliofemoral venous occlusion

2010 ◽  
Vol 52 (1) ◽  
pp. 243-247 ◽  
Author(s):  
Anthony J. Comerota ◽  
Nina K. Grewal ◽  
Subhash Thakur ◽  
Zacaria Assi
Keyword(s):  
Femoral Vein ◽  
Iliac Vein ◽  
Venous Occlusion ◽  
Common Femoral Vein ◽  
The Common

scholarly journals The Dose per Fraction May be correlated with Late Kidney Toxicity after Total Body Irradiation: a Single Institution Experience

2019 ◽  
Vol 2 (1) ◽  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Total Body Irradiation ◽  
Group A ◽  
The Common ◽  
Total Body ◽  
Group B ◽  
Chronic Kidney Disease Group ◽  
Dose Per Fraction

Background: The purpose of the present study was to retrospectively evaluate the subacute or late toxicities in the kidney, lung, and liver after two total body irradiation regimens, 12 Gy in 6 fractions (group A) and 12 Gy in 4 fractions (group B). Methods: Forty-two patients who underwent total body irradiation (group A, n=32; group B, n=10) between June 1997 and June 2013 were included in the present study. The median follow up period was 60 months (range: 3–219 months) for the patients in group A and 143 months (range: 5–220 months) for the patients in group B. We evaluated the renal, pulmonary, and hepatic toxicities using the Common Terminology Criteria for Adverse Events version 4.0. Results: There were 4 cases of chronic kidney disease (group A, n=1; group B, n=3). Although the cumulative incidence of chronic kidney disease differed significantly between the two total body irradiation regimens (p=0.014), the pulmonary and hepatic toxicities did not differ to a statistically significant extent. Conclusion: The present study suggests that a higher dose per fraction caused a higher incidence of chronic kidney disease.

Incidence of Stent Thrombosis after Endovascular Treatment of Iliofemoral or Caval Veins in Patients with the Postthrombotic Syndrome

2019 ◽  
Vol 119 (12) ◽  
pp. 2064-2073 ◽  
Author(s):  
Tim Sebastian ◽  
David Spirk ◽  
Rolf P. Engelberger ◽  
Jörn F. Dopheide ◽  
Frederic A. Baumann ◽  
...  
Keyword(s):  
Stent Thrombosis ◽  
Femoral Vein ◽  
Anticoagulation Therapy ◽  
Duplex Ultrasound ◽  
Incidence Rates ◽  
Postthrombotic Syndrome ◽  
Clinical Trial Registration ◽  
Common Femoral Vein ◽  
The Common

Abstract Background Patients with postthrombotic syndrome (PTS) treated with stents are at risk of stent thrombosis (ST). The incidence of ST in the presence and absence of anticoagulation therapy (AT) is unknown. Risk factors are not well understood. Patients and Methods From the prospective Swiss Venous Stent registry, we conducted a subgroup analysis of 136 consecutive patients with PTS. Incidence of ST was estimated from duplex ultrasound or venography, and reported for the time on and off AT. Baseline, procedural, and follow-up data were evaluated to identify factors associated with ST. Results Median follow-up was 20 (interquartile range [IQR] 9–40) months. AT was stopped in 43 (32%) patients after 12 (IQR 6–14) months. Cumulative incidence of ST was 13.7% (95% confidence interval [CI] 7.8–19.6%) and 21.2% (95% CI 13.2–29.2%) during the first 6 and 36 months, respectively. The time-adjusted incidence rate was 11.2 (95% CI 7.7–16.2) events per 100 patient-years, 11.3 (95% CI 7.3–17.3) for the period on, and 11.2 (95% CI 5.3–23.6) for the period off AT. May–Thurner syndrome (MTS) was associated with decreased incidence of ST (hazard ratio [HR] 0.37, 95% CI 0.15–0.91), whereas age < 40 years (HR 2.26, 95% CI 1.03–4.94), stents below the common femoral vein (HR 3.03, 95% CI 1.28–7.19), and postthrombotic inflow veins (HR 2.92, 95% CI 1.36–6.25) were associated with increased incidence. Conclusion The 6-month incidence of ST was considerably high. Beyond 6 months, consecutive annual incidence rates persisted at 4.1 and 3.4% per year thereafter. Patients with higher incidence of ST were younger, had stents below the common femoral vein, postthrombotic leg inflow veins, and less often MTS. Incidence rates for the period on and off AT must be interpreted with caution. Clinical Trial Registration The study is registered on the National Institutes of Health Web site (ClinicalTrials.gov; identifier NCT02433054).

Hemodynamic significance of collateral blood flow in chronic venous obstruction

2015 ◽  
Vol 30 (1_suppl) ◽  
pp. 27-34 ◽  
Author(s):  
RLM Kurstjens ◽  
MAF de Wolf ◽  
JHH van Laanen ◽  
MW de Haan ◽  
CHA Wittens ◽  
...  
Keyword(s):  
Blood Flow ◽  
Femoral Vein ◽  
Iliac Vein ◽  
Balloon Occlusion ◽  
Collateral Blood Flow ◽  
Venous Obstruction ◽  
Common Femoral Vein ◽  
Thrombotic Disease ◽  
Need For Treatment ◽  
The Common

Introduction Complaints related to the post-thrombotic syndrome do not always correlate well with the extent of post-thrombotic changes on diagnostic imaging. One explanation might be a difference in development of collateral blood flow. The aim of this study is to investigate the hemodynamic effect of collateralisation in deep venous obstruction. Methodology Resting intravenous pressure of the common femoral vein was measured bilaterally in the supine position of patients with unilateral iliofemoral post-thrombotic obstruction. In addition, pressure in control limbs was also measured in the common femoral vein after sudden balloon occlusion in the external iliac vein. Results Fourteen patients (median age 42 years, 12 female) were tested. In eleven limbs post-thrombotic disease extended below the femoral confluence. Median common femoral vein pressure was 17.0 mmHg in diseased limbs compared to 12.8 mmHg in controls (p = 0.001) and 23.5 mmHg in controls after sudden balloon occlusion (p = 0.009). Results remained significant after correcting for non-occlusive post-thrombotic disease. Conclusion This study shows that common femoral vein pressure is increased in post-thrombotic iliofemoral deep venous obstruction, though not as much as after sudden balloon occlusion. The latter difference could explain the importance of collateralisation in deep venous obstructive disease and the discrepancy between complaints and anatomical changes; notwithstanding, the presence of collaterals does not eliminate the need for treatment.

In Well-Selected Patients With a Femoral Deep Vein Thrombosis Central Venous Imaging May Identify Additional Iliocaval Disease

2020 ◽  
Vol 54 (8) ◽  
pp. 681-686
Author(s):  
Chong Li ◽  
Thomas S. Maldonado ◽  
Glenn R. Jacobowitz ◽  
Lowell S. Kabnick ◽  
Michael Barfield ◽  
...  
Keyword(s):  
Deep Vein Thrombosis ◽  
Femoral Vein ◽  
Ultrasound Diagnosis ◽  
Central Venous ◽  
Vein Thrombosis ◽  
Number Of Patients ◽  
Group A ◽  
Group B ◽  
Deep Vein

Objective: Patients who present acutely with a femoral deep vein thrombosis (DVT) diagnosed by ultrasound are often treated with anticoagulation and instructed to follow-up electively. This study sought to assess whether obtaining axial imaging of the central venous system results in the identification of additional iliocaval pathology warranting treatment. Methods: This study was a retrospective review of a prospectively maintained registry from November 2014 through April 2017 with follow-up through March 2020. Consecutive patients with a diagnosis of femoral DVT diagnosed by ultrasound were evaluated; those who underwent axial imaging of the iliocaval system (Group A) were compared to those who did not undergo imaging of the central veins (Group B). The primary outcome was the performance of any percutaneous central venous intervention. Secondary outcomes included the extent of DVT identified on duplex and after axial imaging, follow-up duplex patency and persistence of severe symptoms. Results: Eighty patients presented with an ultrasound diagnosis of a femoral vein DVT. Mean follow-up was 551 ± 502 days. Group A comprised 24 patients (30%) and Group B comprised 56 patients (70%). Baseline demographics did not differ significantly between the 2 groups. After duplex imaging, Group A exhibited an increased prevalence of DVT in the common femoral vein. After central imaging, Group A exhibited an increased prevalence of DVT in the iliocaval veins. The number of patients who underwent invasive treatment differed significantly between the 2 groups, Group A 16/24 (67%) vs. Group B 9/56 (16%), P < 0.0001. The number of patients that demonstrated duplex patency and had persistent symptoms on follow-up did not differ significantly. Conclusions: Patients with an ultrasound diagnosis of femoral DVT may have additional iliocaval pathology warranting intervention. Well-selected imaging of the central veins may reveal a more complete picture, potentially altering management.

Cystic adventitial disease of the common femoral vein: A case report

Vascular ◽  
2020 ◽  
Vol 28 (4) ◽  
pp. 489-493
Author(s):  
Facai Guo ◽  
Yi Guo
Keyword(s):  
Surgical Resection ◽  
Femoral Vein ◽  
Vascular Disorder ◽  
Common Femoral Vein ◽  
Contrast Enhanced ◽  
The Common ◽  
One Year ◽  
Enhanced Computed Tomography ◽  
Contrast Enhanced Computed Tomography

Objectives Cystic adventitial disease is an extremely rare vascular disorder and is often misdiagnosed. In order to improve the knowledge and treatment of this disease, a case of venous cystic adventitial disease was reported. Methods The whole processes about the diagnosis and treatment of one patient with venous cystic adventitial disease was retrospectively studied. Results This case of venous cystic adventitial disease was diagnosed accurately by contrast-enhanced computed tomography and treated successfully by surgical resection. No complications were detected after one-year post-operative follow-up. Conclusions Surgical resection is a safe and effective method for the treatment of venous CAD.

Catheter-Directed Thrombolysis for the Treatment of Acute Iliofemoral Deep Venous Thombosis

2000 ◽  
Vol 15 (3-4) ◽  
pp. 149-155
Author(s):  
A. J. Comerota ◽  
S. A. Kagan
Keyword(s):  
Femoral Vein ◽  
Recombinant Tissue Plasminogen Activator ◽  
Iliac Vein ◽  
Successful Outcome ◽  
Heparin Infusion ◽  
Common Femoral Vein ◽  
Chronic Occlusion ◽  
Catheter Directed Thrombolysis ◽  
Mild Improvement ◽  
The Common

Objective: Acute iliofemoral deep venous thrombosis (DVT) is a serious venous thrombotic disorder with potentially morbid post-thrombotic sequelae. The purpose of this report is to present our single-centre evolution of technique and the results of catheter-directed thrombolysis for the treatment of acute iliofemoral DVT, and put it into perspective with current literature. Patients and methods: Between May 1988 and April 2000, 54 patients were treated with catheter-directed thrombolysis for occlusive iliofemoral and vena caval thrombosis. Average age was 45 years (range 17-68 years) and the duration of leg symptoms was 5.2 days (range 2-30 days). Routine vena caval filters were not used, although caval filters were inserted in patients with irregular and non-occlusive vena caval thrombus. Initially, urokinase infusion via a right jugular vein and/or contralateral femoral vein approach was used, delivering a 250000-500000 U bolus followed by continuous infusion of 250000-300000 LVh. Catheter delivery has evolved to an ultrasound-guided popliteal or posterior tibial vein puncture and the use of recombinant tissue plasminogen activator at a bolus dose of 4–8 mg followed by 2–4 mg/h. All patients received heparin infusion at 500-1000 U/h. Results: Fifty-one of the 54 patients had successful catheter positioning. Forty-five (83%) had a successful outcome. Of those that failed, 2 were treated with a known chronic occlusion and in 2 patients plasminogen deficiency was suspected. Two patients had persistent iliac vein lesions which led to early re-thrombosis. Overall, 14 (26%) were asymptomatic, 28 (52%) demonstrated moderate improvement, 6 (11%) showed mild improvement and 6 (11%) had no clinical improvement. Serious complications occurred in 5 patients (9%). Four (7%) required blood transfusion and 1 (2%) required operative evacuation of an inguinal haematoma with repair of the common femoral vein. Eight patients (15%) developed a puncture site haematoma and 1 patient (2%) had a guidewire perforation of the common femoral vein. Conclusions: Catheter-directed thrombolysis is the preferred treatment for symptomatic iliofemoral DVT. Following successful lysis, residual iliac vein lesions should be corrected with balloon angioplasty and stenting if necessary. Considering the current results and those of contemporary series, a successful outcome can be anticipated in 80-85% of patients, with a significant improvement in quality of life when compared with standard anticoagulation.

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