Gender-based incidence, recovery period, and mortality rate of COVID-19 among the population of district Attock, Pakistan

COVID-19 is reported as an extremely contagious disease with common symptoms of fever, dry cough, sore throat, and tiredness. The published literature on incidence and gender-wise prevalence of COVID-19 is scarce in Pakistan. Therefore, the present study was designed to compare the distribution, incubation period and mortality rate of COVID-19 among the male and female population of district Attock. The data were collected between 01 April 2020 and 07 December 2020 from the population of district Attock, Pakistan. A total of 22,962 individuals were screened and 843 were found positive for RT-qPCR for SARS-CoV-2. The confirmed positive cases were monitored carefully. Among the positive cases, the incidence of COVID-19 was 61.7% among males and 38.2% among females. The average recovery period of males was 18.89±7.75 days and females were 19±8.40 days from SARS-CoV-2. The overall mortality rate was 8.06%. The death rate of male patients was significantly higher (P<0.05) compared to female patients. Also, the mortality rate was higher (P<0.05) in male patients of 40-60 years of age compared to female patients of the same age group. Moreover, the mortality rate significantly increased (P<0.05) with the increase of age irrespective of gender. In conclusion, the incidence and mortality rate of COVID-19 is higher in males compared to the female population. Moreover, irrespective of gender the mortality rate was significantly lower among patients aged <40 years.

Cardiometabolic health profile of young girls with aesthetic professions

Background In the literature, professions that impose body standards for daily performance are designated as non-conventional professions (i.e. models, athletes, ballet dancers), with great emphasis on the female population. More than a job, it becomes a lifestyle to those inserted in this environment, thus, thousands of children and adolescents seek inclusion and success in these professions due to financial and media gains. Such professions are associated with several health-related risk factors. The purpose of this study was to identify and compare among physical fitness levels, cardiometabolic health markers, mental health and dietary habits in non-conventional professions. Methods The sample consisted of 41 female individuals aged between 14 and 24 years, allocated into four groups, control group composed by university students (UG = 11), models (MG = 11), ballet dancers (BG = 11), and athletes’ group (AG = 8). Physical fitness outcomes (cardiorespiratory fitness, flexibility, maximal dynamic strength, muscular endurance and body composition); biochemical outcomes (high-density lipoprotein [HDL], low-density lipoprotein [LDL], total cholesterol [TC], fasting glucose [FG], fasting insulin [FI], C-reactive protein [CRP]), diet quality and mental health were evaluated. Results No impairments were observed in the health markers evaluated among groups, both for health-related physical fitness and biochemical outcomes. However, low levels of bone mineral density (BMD) were observed. Even with statistically significant differences between the groups for chronological age (p = 0.002), menarche (p = 0.004), career length (p = 0.001), height (p = 0.001), body mass index (p = 0.018), waist-to-height ratio (p < 0.001), %Fat (p = 0.020), VO2peak (p = 0.020), maximal dynamic strength of knee extensors (p = 0.031) and elbow flexors (p = 0,001) and flexibility (p < 0.001), all these values are within the normal range for health. Conclusion The professions analyzed do not seem to interfere in the physical fitness and cardiometabolic health of the girls assessed. However, we identified that exposure to these profession can impair mental health (depressive symptoms in 100% of participants) and body composition (BMD 63% of participants).

What impact have Covid-19 pandemic era on violence against women in India - A retrospective comparative research study from January 2018 to December 2021

BackgroundThe safety of women is of significance and prime concern in India due to a huge female population, equity issues, gender issues, lack of positive deviance at community level, illiteracy, socio-economic factors, migration from rural to urban areas, inaccessibility to legal help and of course many more factors. The SARS-CoV-2 pandemic had presented a challenge even for developed nations around the world regarding women’s protection in the ongoing pandemic era &amp; especially in the lockdown period when it’s really difficult to go out and shout for help. Aim and ObjectivesThe main aim of this research is to find out impact of SARS-CoV-2/Covid-19 Pandemic on violence against women in India across different states and union territories from the beginning of pandemic i.e. January 2020. The objective is to find out that the covid-19 era has a positive or negative impact over violence against women. Data from various accredited sources were continuously collected, observed and analysed for this research study. Settings &amp; DesignThe month-wise and state-wise data indicating number of complaints registered with National Commission for Women in India(NCW) under different categories are presented in different table 1, 2, 3, 4,5,6,7,8 will be discussed and displayed. The period of study is from January 2018 to 2021 December. This is a retrospective cross-sectional continuous observational qualitative and quantitative as well as comparative study. The two years of covid-19 pandemic i.e. 2020 and 2021 is compared two previous two years to know the impact of covid-19 on violence against women in India.Materials &amp; MethodologyThe data is collected from accredited and reliable sources of National commission for women, India as well as various other sources listed in this research study. The data obtained is analysed by using Microsoft Office software. To reduce the length of article the detailed description and analysis is not provided in this version.ResultIncrease in violence against women in India is seen in this covid-19 pandemic era as compared to pre-pandemic years under observation. See Figure 1 and figure 2:- comparison of number of cases of domestic violence and various forms of violence to know the impact of SARS-CoV-2 pandemic and lockdown situations in India. During the second year of pandemic i.e. 2021 the total numbers of Nature-Wise Report of the Complaints Received by NCW was 30865 which is an increase by 55.03 % compared to 2018 and 56.43 % as compared to 2019.ConclusionIndia should have various strategies to ensure safety of women and their mental health issues in such pandemic like situations. It seems that present laws and regulations are insufficient to give the desired results. The barriers of legal and protective system and delivery of helpful services etc. constraints should be rectified added with a proper dynamic plan to carry on usual women protection services even in pandemics and natural disasters. Keywords- SARS-CoV-2, pandemic, violence, women, lockdown, domestic abuse,

What impact have Covid-19 pandemic era on violence against women in India - A retrospective comparative research study from January 2018 to December 2021

BackgroundThe safety of women is of significance and prime concern in India due to a huge female population, equity issues, gender issues, lack of positive deviance at community level, illiteracy, socio-economic factors, migration from rural to urban areas, inaccessibility to legal help and of course many more factors. The SARS-CoV-2 pandemic had presented a challenge even for developed nations around the world regarding women’s protection in the ongoing pandemic era & especially in the lockdown period when it’s really difficult to go out and shout for help. Aim and ObjectivesThe main aim of this research is to find out impact of SARS-CoV-2/Covid-19 Pandemic on violence against women in India across different states and union territories from the beginning of pandemic i.e. January 2020. The objective is to find out that the covid-19 era has a positive or negative impact over violence against women. Data from various accredited sources were continuously collected, observed and analysed for this research study. Settings & DesignThe month-wise and state-wise data indicating number of complaints registered with National Commission for Women in India(NCW) under different categories are presented in different table 1, 2, 3, 4,5,6,7,8 will be discussed and displayed. The period of study is from January 2018 to 2021 December. This is a retrospective cross-sectional continuous observational qualitative and quantitative as well as comparative study. The two years of covid-19 pandemic i.e. 2020 and 2021 is compared two previous two years to know the impact of covid-19 on violence against women in India.Materials & MethodologyThe data is collected from accredited and reliable sources of National commission for women, India as well as various other sources listed in this research study. The data obtained is analysed by using Microsoft Office software. To reduce the length of article the detailed description and analysis is not provided in this version.ResultIncrease in violence against women in India is seen in this covid-19 pandemic era as compared to pre-pandemic years under observation. See Figure 1 and figure 2:- comparison of number of cases of domestic violence and various forms of violence to know the impact of SARS-CoV-2 pandemic and lockdown situations in India. During the second year of pandemic i.e. 2021 the total numbers of Nature-Wise Report of the Complaints Received by NCW was 30865 which is an increase by 55.03 % compared to 2018 and 56.43 % as compared to 2019.ConclusionIndia should have various strategies to ensure safety of women and their mental health issues in such pandemic like situations. It seems that present laws and regulations are insufficient to give the desired results. The barriers of legal and protective system and delivery of helpful services etc. constraints should be rectified added with a proper dynamic plan to carry on usual women protection services even in pandemics and natural disasters.

What impact have Covid-19 pandemic era on violence against women in India from January 2020 to December 2021- A Retrospective Research study

BackgroundThe safety of women is of significance and prime concern in India due to a huge female population, equity issues, gender issues, lack of positive deviance at community level, illiteracy, socio-economic factors, migration from rural to urban areas, inaccessibility to legal help and of course many more factors. The SARS-CoV-2 pandemic had presented a challenge even for developed nations around the world regarding women’s protection in the ongoing pandemic era &amp; especially in the lockdown period when it’s really difficult to go out and shout for help. Aim and ObjectivesThe main aim of this research is to find out impact of SARS-CoV-2/Covid-19 Pandemic on violence against women in India across different states and union territories from the beginning of pandemic i.e. January 2020. The objective is to find out that the covid-19 era has a positive or negative impact over violence against women. Data from various accredited sources were continuously collected, observed and analysed for this research study. Settings &amp; DesignThe month-wise and state-wise data indicating number of complaints registered with National Commission for Women in India(NCW) under different categories are presented in different table 1, 2, 3, 4,5,6,7,8 will be discussed and displayed. The period of study is from January 2018 to 2021 December. This is a retrospective cross-sectional continuous observational qualitative and quantitative as well as comparative study. The two years of covid-19 pandemic i.e. 2020 and 2021 is compared two previous two years to know the impact of covid-19 on violence against women in India.Materials &amp; MethodologyThe data is collected from accredited and reliable sources of National commission for women, India as well as various other sources listed in this research study. The data obtained is analysed by using Microsoft Office software. ResultIncrease in violence against women in India is seen in this covid-19 pandemic era as compared to pre-pandemic years under observation. See Figure 1 and figure 2:- comparison of number of cases of domestic violence and various forms of violence to know the impact of SARS-CoV-2 pandemic and lockdown situations in India. During the second year of pandemic i.e. 2021 the total numbers of Nature-Wise Report of the Complaints Received by NCW was 30865 which is an increase by 55.03 % compared to 2018 and 56.43 % as compared to 2019.ConclusionIndia should have various strategies to ensure safety of women and their mental health issues in such pandemic like situations. It seems that present laws and regulations are insufficient to give the desired results. The barriers of legal and protective system and delivery of helpful services etc. constraints should be rectified added with a proper dynamic plan to carry on usual women protection services even in pandemics and natural disasters. Keywords- SARS-CoV-2, pandemic, violence, women, lockdown, domestic abuse,

SARS-CoV-2 infection and COVID-19 vaccination rates in pregnant women in Scotland

Population-level data on COVID-19 vaccine uptake in pregnancy and SARS-CoV-2 infection outcomes are lacking. We describe COVID-19 vaccine uptake and SARS-CoV-2 infection in pregnant women in Scotland, using whole-population data from a national, prospective cohort. Between the start of a COVID-19 vaccine program in Scotland, on 8 December 2020 and 31 October 2021, 25,917 COVID-19 vaccinations were given to 18,457 pregnant women. Vaccine coverage was substantially lower in pregnant women than in the general female population of 18−44 years; 32.3% of women giving birth in October 2021 had two doses of vaccine compared to 77.4% in all women. The extended perinatal mortality rate for women who gave birth within 28 d of a COVID-19 diagnosis was 22.6 per 1,000 births (95% CI 12.9−38.5; pandemic background rate 5.6 per 1,000 births; 452 out of 80,456; 95% CI 5.1−6.2). Overall, 77.4% (3,833 out of 4,950; 95% CI 76.2−78.6) of SARS-CoV-2 infections, 90.9% (748 out of 823; 95% CI 88.7−92.7) of SARS-CoV-2 associated with hospital admission and 98% (102 out of 104; 95% CI 92.5−99.7) of SARS-CoV-2 associated with critical care admission, as well as all baby deaths, occurred in pregnant women who were unvaccinated at the time of COVID-19 diagnosis. Addressing low vaccine uptake rates in pregnant women is imperative to protect the health of women and babies in the ongoing pandemic.

What impact have Covid-19 pandemic era on violence against women in India from January 2020 to December 2021- A Retrospective comparative research study

BackgroundThe safety of women is of significance and prime concern in India due to a huge female population, equity issues, gender issues, lack of positive deviance at community level, illiteracy, socio-economic factors, migration from rural to urban areas, inaccessibility to legal help and of course many more factors. The SARS-CoV-2 pandemic had presented a challenge even for developed nations around the world regarding women’s protection in the ongoing pandemic era & especially in the lockdown period when it’s really difficult to go out and shout for help. Aim and ObjectivesThe main aim of this research is to find out impact of SARS-CoV-2/Covid-19 Pandemic on violence against women in India across different states and union territories from the beginning of pandemic i.e. January 2020. The objective is to find out that the covid-19 era has a positive or negative impact over violence against women. Data from various accredited sources were continuously collected, observed and analysed for this research study.Settings & DesignThe month-wise and state-wise data indicating number of complaints registered with National Commission for Women in India(NCW) under different categories are presented in different table 1, 2, 3, 4,5,6,7,8 will be discussed and displayed. The period of study is from January 2018 to 2021 December. This is a retrospective cross-sectional continuous observational qualitative and quantitative as well as comparative study. The two years of covid-19 pandemic i.e. 2020 and 2021 is compared two previous two years to know the impact of covid-19 on violence against women in India.Materials & MethodologyThe data is collected from accredited and reliable sources of National commission for women, India as well as various other sources listed in this research study. The data obtained is analysed by using Microsoft Office software. To reduce the length of article the detailed description and analysis is not provided in this version.ResultIncrease in violence against women in India is seen in this covid-19 pandemic era as compared to pre-pandemic years under observation. See Figure 1 and figure 2:- comparison of number of cases of domestic violence and various forms of violence to know the impact of SARS-CoV-2 pandemic and lockdown situations in India. During the second year of pandemic i.e. 2021 the total numbers of Nature-Wise Report of the Complaints Received by NCW was 30865 which is an increase by 55.03 % compared to 2018 and 56.43 % as compared to 2019.ConclusionIndia should have various strategies to ensure safety of women and their mental health issues in such pandemic like situations. It seems that present laws and regulations are insufficient to give the desired results. The barriers of legal and protective system and delivery of helpful services etc. constraints should be rectified added with a proper dynamic plan to carry on usual women protection services even in pandemics and natural disasters.

Effects of socio-economic factors on old-age mortality in Russia

Исследование смертности занимает важное место в демографии в целом и в особенности в демографии старения. России свойственна неоднородность демографического развития, в частности региональная дифференциация показателей смертности населения. Работа посвящена анализу зависимости смертности в регионах России в старших возрастных группах от социально-экономических показателей. Исследование проводили с использованием методов регрессионного анализа, где в качестве единиц наблюдения выступали субъекты РФ, в качестве объясняемой переменной - смертность мужского (женского) населения старшего (60+) возраста, представленная в виде стандартизованных по структуре населения коэффициентов. В результате работы выявлены значимые социально-экономические факторы, позволяющие объяснить различия уровней смертности в субъектах РФ. Studies of old-age mortality are an important part of demography, especially the demography of ageing. Demographic development of Russia is characterized by heterogeneity including regional differences in mortality. The aim of the paper is to analyze the dependence of mortality at old-age groups on socio-economic indicators. The study is conducted using methods of regression analysis; the units of observation are the regions of the Russian Federation, the explained variable is the mortality rate of male (female) population at older (60+) ages standardized by the population-age structure. As a result, the significant socio-economic factors, explaining the differences of mortality rates in the regions of the Russian Federation, were identified.

Simultaneous measurement of intra-epidermal electric detection thresholds and evoked potentials for observation of nociceptive processing following sleep deprivation

Sleep deprivation has been shown to increase pain intensity and decrease pain thresholds in healthy subjects. In chronic pain patients, sleep impairment often worsens the perceived pain intensity. This increased pain perception is the result of altered nociceptive processing. We recently developed a method to quantify and monitor altered nociceptive processing by simultaneous tracking of psychophysical detection thresholds and recording of evoked cortical potentials during intra-epidermal electric stimulation. In this study, we assessed the sensitivity of nociceptive detection thresholds and evoked potentials to altered nociceptive processing after sleep deprivation in an exploratory study with 24 healthy male and 24 healthy female subjects. In each subject, we tracked nociceptive detection thresholds and recorded central evoked potentials in response to 180 single- and 180 double-pulse intra-epidermal electric stimuli. Results showed that the detection thresholds for single- and double-pulse stimuli and the average central evoked potential for single-pulse stimuli were significantly decreased after sleep deprivation. When analyzed separated by sex, these effects were only significant in the male population. Multivariate analysis showed that the decrease of central evoked potential was associated with a decrease of task-related evoked activity. Measurement repetition led to a decrease of the detection threshold to double-pulse stimuli in the mixed and the female population, but did not significantly affect any other outcome measures. These results suggest that simultaneous tracking of psychophysical detection thresholds and evoked potentials is a useful method to observe altered nociceptive processing after sleep deprivation, but is also sensitive to sex differences and measurement repetition.

Mitochondrial DNA Footprints from Western Eurasia in Modern Mongolia

Mongolia is located in a strategic position at the eastern edge of the Eurasian Steppe. Nomadic populations moved across this wide area for millennia before developing more sedentary communities, extended empires, and complex trading networks, which connected western Eurasia and eastern Asia until the late Medieval period. We provided a fine-grained portrait of the mitochondrial DNA (mtDNA) variation observed in present-day Mongolians and capable of revealing gene flows and other demographic processes that took place in Inner Asia, as well as in western Eurasia. The analyses of a novel dataset (N = 2,420) of mtDNAs highlighted a clear matrilineal differentiation within the country due to a mixture of haplotypes with eastern Asian (EAs) and western Eurasian (WEu) origins, which were differentially lost and preserved. In a wider genetic context, the prevalent EAs contribution, larger in eastern and central Mongolian regions, revealed continuous connections with neighboring Asian populations until recent times, as attested by the geographically restricted haplotype-sharing likely facilitated by the Genghis Khan’s so-called Pax Mongolica. The genetic history beyond the WEu haplogroups, notably detectable on both sides of Mongolia, was more difficult to explain. For this reason, we moved to the analysis of entire mitogenomes (N = 147). Although it was not completely possible to identify specific lineages that evolved in situ, two major changes in the effective (female) population size were reconstructed. The more recent one, which began during the late Pleistocene glacial period and became steeper in the early Holocene, was probably the outcome of demographic events connected to western Eurasia. The Neolithic growth could be easily explained by the diffusion of dairy pastoralism, as already proposed, while the late glacial increase indicates, for the first time, a genetic connection with western Eurasian refuges, as supported by the unusual high frequency and internal sub-structure in Mongolia of haplogroup H1, a well-known post-glacial marker in Europe. Bronze Age events, without a significant demographic impact, might explain the age of some mtDNA haplogroups. Finally, a diachronic comparison with available ancient mtDNAs made it possible to link six mitochondrial lineages of present-day Mongolians to the timeframe and geographic path of the Silk Route.