scholarly journals 271 Treatment of thrombophlebitic necrotic lesions in a patient with syncardia—a case report

2021 ◽  
Vol 23 (Supplement_G) ◽  
Author(s):  
Gaetano Artiola ◽  
Vincenzo Pettillo

Abstract Aims The 58 years old male patient with an important dilated cardiomyopathy, carrier of ICD, numerous malignant arrhythmias (VT) and without the possibility of a timely heart transplant, underwent emergency surgery by implanting a total artificial heart syncardia. Necrotic tissue was already present on the forearm and in the antecubital region before the surgery; it was caused by extravasation and thrombophlebitis due to continuous intravenous therapies and the lesions were deep down to tendons and bones after a surgical toilet. Years of unstable haemodynamics caused by dilated cardiomyopathy and low cardiac output led to poor peripheral vascularization giving priority to noble structures. Restoration of the tissue using advanced dressings without the use of skin grafts avoiding bacterial infections in a fragile patient. Methods and results A Pubmed search for advanced dressings was performed and a Webinar on the Wound Hygiene technique was attended. In the first instance, a polyurethane foam dressing was used and the wound on the forearm showed major improvements, subsequently with the synergistic help of the ‘Wound Hygiene’ technique and dressings based on connectivine, the tissue healed. The wound located in the antecubital region had continuous biofilm formation and a VacTherapy was planned for this. After 7 days, the conditions worsened and for this reason it was decided to use the Aqua Cell Ag +. This dressing with the silver helps in the formation of granulation tissue and it also prevents infections ‘trapping’ bacteria inside it. Conclusions The use of dressings with the Wound Hygiene technique led to the formation of new tissue without the need to perform a skin graft in a patient with a total artificial heart and without bacterial infections.

2012 ◽  
Vol 60 (S 01) ◽  
Author(s):  
Y Brocks ◽  
M Schoenbrodt ◽  
M Morshuis ◽  
J Gummert ◽  
K Tigges-Limmer

2015 ◽  
Vol 135 (11) ◽  
pp. 1376-1385
Author(s):  
Kentaro Ohnuma ◽  
Hirohito Sumikura ◽  
Tomonori Tsukiya ◽  
Eisuke Tatsumi ◽  
Yoshiyuki Taenaka ◽  
...  

2021 ◽  
Vol 40 (4) ◽  
pp. S528
Author(s):  
G.T. Gibson ◽  
S. Rangasamy ◽  
J. Contreras ◽  
A. Singhvi ◽  
A. Fox ◽  
...  

Nanomaterials ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 1046
Author(s):  
Yinghan Chan ◽  
Xun Hui Wu ◽  
Buong Woei Chieng ◽  
Nor Azowa Ibrahim ◽  
Yoon Yee Then

Biofilm formation represents a significant cause of concern as it has been associated with increased morbidity and mortality, thereby imposing a huge burden on public healthcare system throughout the world. As biofilms are usually resistant to various conventional antimicrobial interventions, they may result in severe and persistent infections, which necessitates the development of novel therapeutic strategies to combat biofilm-based infections. Physicochemical modification of the biomaterials utilized in medical devices to mitigate initial microbial attachment has been proposed as a promising strategy in combating polymicrobial infections, as the adhesion of microorganisms is typically the first step for the formation of biofilms. For instance, superhydrophobic surfaces have been shown to possess substantial anti-biofilm properties attributed to the presence of nanostructures. In this article, we provide an insight into the mechanisms underlying biofilm formation and their composition, as well as the applications of nanomaterials as superhydrophobic nanocoatings for the development of novel anti-biofilm therapies.


Sign in / Sign up

Export Citation Format

Share Document