Potential health hazards of assisted human reproduction: Effects of manipulations in vitro of human oocytes and embryos on the birthweight of the resultant babies

1995 ◽  
Vol 10 (6) ◽  
pp. 1322-1324 ◽  
Author(s):  
J. J. Tarin ◽  
A. Cano
Keyword(s):  
Health Hazards ◽  
Human Reproduction ◽  
Potential Health ◽  
Human Oocytes ◽  
Assisted Human Reproduction

In vitro fertilisation of mouse oocytes reconstructed by transfer of metaphase II chromosomes results in live births

Zygote ◽  
2001 ◽  
Vol 9 (1) ◽  
pp. 9-14 ◽  
Author(s):  
Min-Kang Wang ◽  
Da-Yuan Chen ◽  
Ji-Long Lui ◽  
Guang-Peng Li ◽  
Qing-Yuan Sun
Keyword(s):  
Nuclear Transfer ◽  
Normal Structure ◽  
Human Reproduction ◽  
In Vitro Fertilisation ◽  
Kunming Mouse ◽  
Mouse Oocytes ◽  
Assisted Human Reproduction ◽  
And Function ◽  
Apparatus Transfer

The interaction between nucleus and cytoplasm can be explored through nuclear transfer. We describe here another tool to investigate this interaction: MII meiotic apparatus transfer (MAT) between mouse oocytes. In this study, the MII oocyte meiotic apparatus or spindle from C57BL/6 mice, a black strain, was transferred into an enucleated metaphase oocyte from Kunming mouse, a white strain. The results showed that the enucleation rate by treating oocytes with 3% sucrose was 100%, but the electrofusion efficiency was very low, with only 17.6% of reconstructed karyoplast-recipient cytoplasm pairs fused. When the fused oocytes were exposed to spermatozoa from C57BL/6 mice, 9 of 11 (82%) were fertilised. Eight reconstructed embryos at 1- to 4-cell stages were transferred into the oviducts of two synchronously pregnant Kunming strain fosters and one delivered two normal C57BL/6 offspring. This study indicates that MII meiotic apparatus or spindle sustains normal structure and function after micromanipulation and electrofusion. MAT provides a model for further research on the application of this technique to assisted human reproduction.

scholarly journals Técnicas de reproducción humana asistida en el sistema argentino: una visión desde los derechos humanos / Assisted human reproduction techniques in the Argentine system: a vision from human rights

2019 ◽  
pp. 279-318
Author(s):  
María Florencia Belanti
Keyword(s):  
Human Rights ◽  
Right To Health ◽  
Human Reproduction ◽  
System A ◽  
Assisted Human Reproduction ◽  
Derechos Humanos ◽  
Legal Situation ◽  
El Sistema ◽  
The Right

La resolución que se comenta nos estimula a reflexionar sobre las técnicas de reproducción humana asistida con una mirada inescindible desde el prisma de derechos humanos. En este ámbito, se pretende llevar a cabo un análisis desde el derecho a la salud en general y a la salud reproductiva en particular, efectuando una reseña normativa de la materia, una exploración del precedente específico en el ámbito interamericano y una reflexión sobre la situación jurídica del embrión in vitro.   The resolution discussed encourages us to reflect on assisted human reproduction techniques with an inescisible look from the perspective of human rights. In this area, it is intended to carry out an analysis from the right to health in general and to reproductive health in particular, making a normative review of the matter, an exploration of the specific precedent in the inter-American sphere and a reflection on the legal situation of the embryo in vitro

scholarly journals The regulation of stem cell research in Ireland: From the Commission on Assisted Human Reproduction to the Assisted Human Reproduction Bill 2017

2018 ◽  
Vol 18 (1) ◽  
pp. 35-58
Author(s):  
Ciara Staunton
Keyword(s):  
Stem Cell ◽  
Stem Cell Research ◽  
General Scheme ◽  
Embryonic Stem ◽  
Human Reproduction ◽  
Assisted Human Reproduction ◽  
The Right ◽  
The Impact

In 2005, Ireland’s Commission on Assisted Human Reproduction (CAHR) published a comprehensive report on the regulation of assisted reproduction and associated technologies. Yet since that report, successive Irish governments have failed to bring forth any legislation on this matter. This legislative inaction has resulted in a situation whereby the embryo in vivo has the right to life under the Irish Constitution, but embryos in vitro have no protection in law. Irish policymakers have also endorsed and funded embryonic stem cell research (ESCR) at a European level but continue to prevent researchers in Ireland from accessing any public funds for this research. The publication in October 2017 of the General Scheme of the Assisted Human Reproduction Bill 2017 is thus a welcome development. However, further reading of the Bill reveals that it is restrictive in nature and is likely to stifle research in Ireland. This article will discuss the legal, ethical and scientific developments that have occurred since the CAHR report and the impact, if any, they have had on the development of this Bill. It will critically reflect on provisions of the Bill as they relate to ESCR and make a number of suggestions for reform.

Sign in / Sign up

Export Citation Format

Share Document