Turbidimetric Determination of Soluble Sulfates in Water-Soluble Color Additives

1970 ◽  
Vol 53 (2) ◽  
pp. 242-243
Author(s):  
Nancy Kay Hobin
Keyword(s):  
Activated Carbon ◽  
Sodium Sulfate ◽  
Barium Sulfate ◽  
Water Soluble ◽  
Color Additive ◽  
Soluble Sulfates

Abstract A turbidimetric procedure is described forthe determination of soluble sulfates in water-soluble color additives. The color additive is adsorbed on activated carbon, the sulfates in the filtrate are precipitated as barium sulfate, and the turbidity is measured spectrophotometrically at 440 nm . The precision of this method is m0.1% in the range of 0.1–2.5% sodium sulfate.

Automatic Potentiometric Titration of Sodium Sulfate in Certifiable Water-Soluble Colors

1974 ◽  
Vol 57 (2) ◽  
pp. 353-355
Author(s):  
John E Bailey ◽  
Charles Graichen
Keyword(s):  
Sample Preparation ◽  
Potentiometric Titration ◽  
Sodium Sulfate ◽  
Nitrate Solution ◽  
Lead Nitrate ◽  
Reference Electrode ◽  
Water Soluble ◽  
Automatic Titrator

Abstract A method has been developed for the automatic potentiometric titration of sulfate in water-soluble colors, which has the advantage of requiring little sample preparation and attention. A platinum indicating electrode is used with a coated silver reference electrode. The colors are dissolved in 75% alcohol. The sulfate is titrated with lead nitrate solution, using a Hiranuma recording automatic titrator. The method is applicable to the determination of sulfate in all sulfonated certifiable water-soluble colors except External D&C Green No. 1. It is not applicable to the determination of sulfate in the certifiable water-soluble fluorescein colors, namely, FD&C Red No. 3, D&C Orange No. 11, D&C Red No. 22, D&C Red No. 28, and D&C Yellow No. 8. The method is also not applicable to D&C Red No. 19. The

Simultaneous Spectrophotometric Determination of Salbutamol by Coupling with Diazotized 4-Aminobenzoic acid

2017 ◽  
Vol 8 (1) ◽  
Author(s):  
Hind Hadi ◽  
Gufran Salim
Keyword(s):  
Pharmaceutical Preparations ◽  
Coupling Reaction ◽  
Dosage Forms ◽  
Water Soluble ◽  
Trace Determination ◽  
Aminobenzoic Acid ◽  
Optimum Conditions ◽  
Colored Product ◽  
Versus Concentration

A simple, rapid and sensitive spectrophotmetric method for trace determination of salbutamol (SAL) in aqueous solution and in pharmaceutical preparations is described. The method is based on the diazotization coupling reaction of the intended compound with 4-amino benzoic acid (ABA) in alkaline medium to form an intense orange, water soluble dye that is stable and shows maximum absorption at 410 nm. A graph of absorbance versus concentration indicates that Beer’s law is obeyed over the concentration range of 0.5-30 ppm, with a molar absorbtivity 3.76×104 L.mol-1 .cm-1 depending on the concentration of SAL. The optimum conditions and stability of the colored product have been investigated and the method was applied successfully to the determination of SAL in dosage forms.

Sign in / Sign up

Export Citation Format

Share Document