Determination of Ethylene Oxide and Ethylene Chlorohydrin in Plastic and Rubber Surgical Equipment Sterilized with Ethylene Oxide

1970 ◽  
Vol 53 (2) ◽  
pp. 263-267
Author(s):  
Daniel J Brown
Keyword(s):  
Detection Limit ◽  
Ethylene Oxide ◽  
Chromatographic Analysis ◽  
Ethylene Chlorohydrin ◽  
Surgical Equipment ◽  
Lower Detection Limit ◽  
Lower Detection ◽  
Liquid Chromatographic Analysis ◽  
Liquid Chromatographic

Abstract A method is presented for the determination of ethylene chlorohydrin and ethylene oxide residues in plastic and rubber surgical equipment. Samples are extracted with p-xylene and the desired constituents are isolated by column chromatography. Ethylene oxide is converted to ethylene chlorohydrin on a Celite column. Sweep co-distillation is then employed for further purification, if necessary, before gas-liquid chromatographic analysis. The lower detection limit is approximately 25 ng. Recoveries of 3.5’50 ppm chlorohydrin from 20’35 g samples range from 64 to 100%, depending on the absorbing capacity of the material being analyzed and the condition of the adsorbent.

Determination of serum retinol (vitamin A) by high-speed liquid chromatography.

1976 ◽  
Vol 22 (10) ◽  
pp. 1593-1595 ◽  
Author(s):  
M G De Ruyter ◽  
A P De Leenheer
Keyword(s):  
Liquid Chromatography ◽  
Detection Limit ◽  
Vitamin A ◽  
High Speed ◽  
Serum Retinol ◽  
Lower Detection Limit ◽  
Serum Pool ◽  
Lower Detection ◽  
Liquid Chromatographic

Abstract We report a fast and simple high-speed liquid-chromatographic assay for serum retinol. Only 100 mul of serum is required. The lower detection limit is 50 mug/liter; linearity was demonstrated up to 1.50 mg/liter. On analyzing a serum pool eight times, a CV of 2.5% was obtained. Values by this method are compared with results obtained by a flurometric method [Clin. Chem. 16, 766(1970)].

Gas-Liquid Chromatographic Analysis and Chemical Confirmation of Azodrin (Monocrotophos) Residues in Strawberries

1976 ◽  
Vol 59 (3) ◽  
pp. 637-640
Author(s):  
James F Lawrence ◽  
Harry A McLeod
Keyword(s):  
Detection Limit ◽  
Chromatographic Analysis ◽  
Small Volume ◽  
Anhydrous Sodium Sulfate ◽  
Methylene Chloride ◽  
Photometric Detection ◽  
Flame Photometric Detection ◽  
Fresh Frozen ◽  
Liquid Chromatographic Analysis ◽  
Liquid Chromatographic

Abstract A gas-liquid chromatographic (GLC) method is described for the analysis and confirmation of azodrin (monocrotophos, 3-(dimethoxyphosphinyl)-N-methyl-cis-crotonamide) residues in strawberries. The strawberries are extracted with acetone, and the filtrate is partitioned with a mixture of methylene chloride and petroleum ether followed by further extraction with methylene chloride. The organic phases are combined, dried with anhydrous sodium sulfate, and concentrated to a small volume for GLC analysis on a 3% OV-210 column with flame photometric detection. Identity of the compound is confirmed by chromatography on the same column after trifluoroacetylation of an aliquot of the strawberry extract. The detection limit is about 2 ppb. The types of strawberry samples analyzed were fresh, frozen, pureed, and jam.

Improved Spectrophotometric Determination of Cyclopiazonic Acid in Poultry Feed and Corn

1990 ◽  
Vol 73 (2) ◽  
pp. 257-259 ◽  
Author(s):  
Ivan Chang-Yen ◽  
Keshore Bidasee
Keyword(s):  
Detection Limit ◽  
Spectrophotometric Determination ◽  
Spectrophotometric Method ◽  
Cyclopiazonic Acid ◽  
Poultry Feed ◽  
Reaction Conditions ◽  
Lower Detection Limit ◽  
Lower Detection ◽  
Feed Samples

Abstract An improved visible spectrophotometric method has been developed for cyclopiazonic acid in poultry feed and corn. The method Is based on the reaction of cyclopiazonic acid with Ehrlich reagent and detection at 580 nm. Reaction conditions were optimized with respect to reaction and measurement times and acid and Ehrlich reagent concentrations. Calibration curves were linear from 1 to 20 μg cyclopiazonic acid in 3 mL Ehrlich reagent, with a lower detection limit of 0.08 mg/kg for 50 g samples of poultry feed and corn. Recoveries from 50 g samples of poultry feed spiked with cyclopiazonic ranging from 0.16 to 1.20 mg/kg averaged 93.8%. Moldy corn and poultry feed samples analyzed by this method contained between 1 and 4 mg/kg cyclopiazonic acid.

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