Liquid Chromatographic Determination of Nystatin in Pharmaceutical Preparations
2001 ◽
Vol 84
(4)
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pp. 1050-1056
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Keyword(s):
Abstract A rapid, reversed-phase liquid chromatographic method was developed for the assay of nystatin in the bulk drug and a variety of dosage forms. Analysis was performed on a Symmetry C18 reversed-phase column using a mobile phase of methanol–water–dimethylformamide (DMF; 55 + 30 + 15, v/v/v), with detection by UV at 305 nm. Quantitation is based on the sum of the peak areas of the 2 major isomers of nystatin. The linearity of the assay was determined for a concentration range of 0.05 to 0.2 mg/mL (correlation coefficient > 0.999). Accuracies and precision showed good reproducibility.
1995 ◽
Vol 78
(2)
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pp. 307-309
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1993 ◽
Vol 76
(6)
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pp. 1248-1254
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1994 ◽
Vol 77
(6)
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pp. 1689-1694
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2000 ◽
Vol 22
(4)
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pp. 699-703
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1992 ◽
Vol 75
(1)
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pp. 62-65
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2005 ◽
Vol 39
(3-4)
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pp. 819-823
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1992 ◽
Vol 75
(3)
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pp. 561-565
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2001 ◽
Vol 84
(3)
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pp. 676-683
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1989 ◽
Vol 72
(2)
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pp. 231-234
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