scholarly journals Stimulation of Epithelial Cell Proliferation of Isolated Distal Colon of Rats by Continuous Colonic Infusion of Ammonia or Short-Chain Fatty Acids Is Nonadditive

1998 ◽  
Vol 128 (5) ◽  
pp. 843-847 ◽  
Author(s):  
Hirofumi Ichikawa ◽  
Takashi Sakata
2016 ◽  
Vol 12 (7) ◽  
pp. 637-646 ◽  
Author(s):  
Pittaya Chaikham ◽  
Arunee Apichartsrangkoon ◽  
Srivilai Worametrachanon ◽  
Tom Van de Wiele

Abstract The prospect of Lactobacillus casei 01 and pasteurized purple-rice drinks on modulating colon microbiome by using a simulator of the human intestinal microbial ecosystem was investigated. Accordingly, L. casei 01 alone and with pasteurized purple-rice drink were administered into the proximal and distal colons. In consequence, some colon bacteria and their metabolic activities were examined. The results showed that upon modulating the colon microbiota by L. casei 01 alone with pasteurized germinated-purple-rice drink in the distal colon, acetate and propionate (short-chain fatty acids) were equivalently elevated but other treatments performed differently. Based on the profile of colon microbiota, most treatments stimulated the highest number of lactobacilli followed by bifidobacteria, while other undesirable bacteria were moderately diminished. In overall, larger gelatinized starch in the rice drinks enabled by pasteurization triggered off better modulating impact than by pressurization.


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